Results 71 to 80 of about 314,751 (339)

Markedly enhanced intratumoral spread and antitumor effect of oncolytic adenovirus expressing decorin [PDF]

open access: yes, 2008
With the aim of improving viral distribution and tumor penetration, we have engineered decorin expressing replication-incompetent (dl-LacZ-DCNG) and -competent (Ad-[DELTA]E1B-DCNG) adenoviruses.
A-Rum Yoon   +7 more
core   +1 more source

Rotavirus and adenovirus in Rondônia [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 2007
Acute gastroenteritis is one of the most common diseases in humans worldwide. Viral gastroenteritis is a global problem in infants and young children. In this study the incidence of diarrhea was assessed in 877 hospitalized children under five years old, over a period of 24 months and distributed in 470 cases of diarrhea and 407 age-matched group with ...
Magalhães, Gleiciene Félix   +5 more
openaire   +5 more sources

PRDM16 Reduces Cellular Senescence by Upregulating GSTM1

open access: yesAdvanced Science, EarlyView.
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan   +7 more
wiley   +1 more source

Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin α\(_4\)β\(_7\) [PDF]

open access: yes, 2009
Background: The Step Study was a randomized trial to reduce HIV infection through vaccination with an adenovirus type 5-based gag/pol/nef construct; analysis following early cessation of the trial revealed an excess of HIV seroconversion in Ad5 ...
Chakupurakal, Geothy   +4 more
core   +1 more source

Adenovirus infections

open access: yesMedicine, 2001
Adenoviruses are common causes of febrile illness in early childhood. They are most often associated with respiratory tract disease, but can also cause gastrointestinal, ophthalmological, cardiac, neurological and genitourinary manifestations. Viral culture is a sensitive method for detecting most adenoviruses.
openaire   +2 more sources

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

open access: yesAdvanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv   +11 more
wiley   +1 more source

Integrated assessment of groundwater contamination: A multi-marker approach for comprehensive water quality monitoring

open access: yesWater Supply
This study investigated the presence of adenoviral markers (Library-Independent microbial source tracking tool) in the groundwater of Ludhiana, Punjab, India, a hitherto unexplored area. While deep aquifers post-chlorination were adenovirus free, shallow
Asima Zehra   +3 more
doaj   +1 more source

ENTERIC ADENOVIRUS INFECTION IN INFANTS AND YOUNG CHILDREN WITH ACUTE GASTROENTERITIS IN TEHRAN [PDF]

open access: yesActa Medica Iranica, 2006
Adenoviruses are one of the most important etiological agents of serious gastroenteritis among infants and young children. Fecal specimens from patients with an acute gastroenteritis were evaluated for the presence of adenovirus (Ad40, 41) from April ...
F. Jam-Afzon S. Modarres, S. Modarres
doaj   +2 more sources

Adenovirus transduction of 3T3-L1 cells

open access: yesJournal of Lipid Research, 2001
3T3-L1 cells offer an excellent model system for studies of differentiation and biochemistry of fat cells. However, these cells are limited in their utility by the low efficiency with which DNA can be introduced by transfection.
David J. Orlicky, Jerome Schaack
doaj   +1 more source

Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver. [PDF]

open access: yes, 2007
We administered an adenoviral vector, Onyx-015, into the hepatic artery of patients with metastatic colorectal cancer involving the liver. Thirty-five patients enrolled in this multi-institutional phase I/II trial received up to eight arterial infusions ...
Au, T   +5 more
core  

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