Results 91 to 100 of about 122,429 (294)
British Journal of Clinical Pharmacology, EarlyView.Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind +7 more
wiley +1 more source
Adenovirus infection enhances in vitro adherence of Streptococcus pneumoniae
, 1994 Viruses are thought to facilitate bacterial infections of the respiratory tract, but the mechanisms are poorly understood. The present study analyzed the effect of adenovirus on bacterial adherence to human respiratory tract epithelial cells.
Svanborg, C, +5 more
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What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Biotechnology and Bioengineering, EarlyView.Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
The Polypeptides of Adenovirus-infected Cells
Journal of General Virology, 1972 Summary The polypeptides of cells which had been infected with adenovirus and pulse labelled with high specific activity [35S]-methionine have been examined by polyacrylamide gel electrophoresis followed by autoradiography. Five virus-particle polypeptides and at least five other polypeptides which appeared to be specific for the infected cell could be
W C, Russell, J J, Skehel
openaire +2 more sources
A Community-Derived Outbreak of Adenovirus Type 3 in Children in Taiwan between 2004 and 2005
, 2009 An outbreak of respiratory adenovirus infection in children was observed in northern Taiwan between November 2004 and February 2005. Using polymerase chain reaction-restriction fragment length polymorphism (PCR- RFLP) to determine the serotype(s) of 172 ...
CHANG, SUI-YUAN;LEE, CHUN-NAN;HUANG, HSUEH-HUANG;CHANG, LUAN-YIN;CHANG, SHU- FANG;LEE, PING-ING;HUANG, LI-MIN;KAO, CHUAN-LIANG +1 more
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Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, EarlyView.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Determining new functions of Adenovirus VA-RNAI and its use in cancer therapy
, 2009 PhDVirus-Associated RNA I (VA-RNAI; VAI) of adenovirus is a nontranslated RNA molecule known to interact with several dsRNA-binding molecules in host cells.
Binny, Christopher Jonathan
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Cancer Nexus, EarlyView.ABSTRACT Aim Persistent high‐risk HPV infection can lead to the development of precancerous lesions, potentially progressing to invasive cancer. HPV status serves not only as a prognostic marker for squamous cell carcinoma (HNSCC) like oropharyngeal squamous cell carcinomas (OPSCC) but also significantly influences clinical management and treatment ...
Min Wang +9 more
wiley +1 more source
The transcriptome of the adenovirus infected cell
Virology, 2012 Alternations of cellular gene expression following an adenovirus type 2 infection of human primary cells were studied by using superior sensitive cDNA sequencing. In total, 3791 cellular genes were identified as differentially expressed more than 2-fold.
Zhao H +4 more
openaire +3 more sources
Studies of the adenovirus 5 L1 gene aimed at developing L1 gene deficiencies for use in gene therapy vectors [PDF]
Gene therapy is a novel approach to the treatment of human disease that is in its very early stages of development. Its purpose is to add to and/or alter the pattern of gene expression in cells so as to achieve a therapeutic benefit and is being ...
Arslanoglu, Alper
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