Results 81 to 90 of about 122,429 (294)

Intracranial transplantation of the tumor induced by adenovirus type 12 in Syrian hamster--an experimental brain tumor model

, 1971
A method of intracranial transplantation of the tumor induced by adenovirus type 12 in syrian hamster has been described. The incidence of intracranial tumor development was 86 (90.5 %) out of 95 animals and the average survival time and tumor size at ...
Tabuchi, Kazuo
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The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Ileocecal Intussusception with Histomorphological Features of Inflammatory Neuropathy in Adenovirus Infection

Gastroenterology Research and Practice, 2009
The pathophysiological mechanisms for ileocecal intussusception in children with adenovirus infection are not well characterized. Here we demonstrate coincidence of adenovirus infection and inflammatory neuropathy of myenteric plexus in two children with
Elke Kaemmerer, Jens J. W. Tischendorf, Gerd Steinau, Norbert Wagner, Nikolaus Gassler   +4 more
doaj   +1 more source

Adenovirus and its interaction with host cell proteins

, 2007
The E1B55k gene in adenovirus type 5 was studied by generating recombinant viruses in which the E1B55k gene was N-terminally tagged with either a cyan fluorescent protein (CFP) tag or a tandem affinity purification (TAP) tag.
Carr, Sharon
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Distribution of Adenovirus and Rotavirus by Age and Seasons in Children Diagnosed with Viral Gastroenteritis

, 2021
Introduction: This study aimed to analyze the distribution of rotavirus and adenovirus in pediatric patients according to the age and seasons of infection.
Demet Hacıseyitoğlu, Yakup Çağ
core   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Exploring the link between adenovirus infection and Guillain-Barré syndrome in children: a case-based analysis

The Turkish Journal of Pediatrics
Background. Adenovirus infections are commonly associated with respiratory tract infections, conjunctivitis, gastrointestinal disturbances, and in some cases, more severe illnesses such as pneumonia.
Gulrukh Tuychiboeva, İbrahim Öncel, Gökçen Çoban Çifci, Ali Bülent Cengiz, Kübra Aykaç   +4 more
doaj   +1 more source

The role of PML proteins in adenovirus type 5 infection and the type I interferon response [PDF]

Promyelocytic leukaemia (PML) proteins consist of a collection of related isoforms that are the nucleating components of sub-nuclear structures termed PML nuclear bodies (PML NBs). Numerous functions are attributed to PML and PML NBs, including a role
Wright, Jordan
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Nuclear actin and myosins in adenovirus infection [PDF]

, 2015
Adenovirus serotypes have been shown to cause drastic changes in nuclear organization, including the transcription machinery, during infection. This ability of adenovirus to subvert transcription in the host cell facilitates viral replication.
Serebryannyy, Leonid A., De Lanerolle, Primal, Fuchsova, Beata   +2 more
core   +1 more source

In vitro co-infection by cytomegalovirus improves the antiviral activity of ganciclovir against human adenovirus

, 2021
Human adenovirus (HAdV) infection has an important clinical impact in the immunosuppressed population and is associated with high morbidity and mortality rates.
Sánchez-Céspedes, Javier, Merino Díaz, Laura, Aguilar Guisado, Manuela, Berastegui-Cabrera, Judith, Pachón, Jerónimo, Marrugal-Lorenzo, José Antonio   +5 more
core   +1 more source