Results 201 to 210 of about 45,608 (300)

Identification and Characterization of a Novel Bovine Adenovirus Which Represents a Distinct Evolutionary Branch. [PDF]

Viruses
Sui J, Wang S, Pan Z, Wang K.
europepmc   +1 more source

Amino acid residues L261, W264, F265, L268, and V269 of apolipoprotein E4 critically regulate adipose tissue metabolism. [PDF]

J Lipid Res
Zvintzou E, Giannopoulou PC, Giannatou K, Ionita R, Alemi M, Kakafoni G, Mparnia V, Dumitrescu M, Fenyo IM, Gafencu AV, Kypreos KE.   +10 more
europepmc   +1 more source

Design and Engineering of Recombinant Oncolytic Adenoviruses Expressing an Anti-EpCAM/Anti-CD3 BiTE for Targeted Immunotherapy of A549 Lung Cancer Cells. [PDF]

Onco Targets Ther
Taheri E, Abdoli S, Shahbazi M.
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Emergence and Pathogenicity of a Novel Goose Adenovirus Type 4 Strain JA2485: Insights for Poultry Disease Control. [PDF]

Viruses
Li B, Chang J, Cao X, Zhou W, Liu L, Gao W, Huang Z, Liu J, Zhou X, Liu Y, Song Y, Li X.   +11 more
europepmc   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

CV1 Chimpanzee Adenovirus Efficiently Transduces Mesenchymal Stem and Leukemia Cells: Implications for Cellular Targeting and Vector Tropism. [PDF]

Cancers (Basel)
Tripodi L, Vitale M, Izzo B, Scialò F, Lombardo B, Pastore L.   +5 more
europepmc   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

CD46 and DSG2 synergistically mediate human adenovirus type 7 infection. [PDF]

J Virol
Ye L, Mo C, Yuan J, Su Y, Zhou C, Yang Y, Li X, Liu W, Zeng R, Zhou R, Tian X.   +10 more
europepmc   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source