Results 181 to 190 of about 45,608 (300)

p53-armed oncolytic adenovirus induces apoptosis in pancreatic cancer-associated stellate cells via macropinocytosis. [PDF]

Cancer Gene Ther
Nishiyama T, Tazawa H, Nagai Y, Shoji R, Kajiwara Y, Hashimoto N, Takahashi Y, Kikuchi S, Kuroda S, Ohara T, Noma K, Yoshida R, Umeda Y, Tanaka HY, Kano MR, Masamune A, Urata Y, Kagawa S, Fujiwara T.   +18 more
europepmc   +1 more source

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Early-life infection dynamics and genomic diversity of adenoviruses in a wild primate (<i>Theropithecus gelada</i>). [PDF]

Microb Genom
Saroff MJ, Haile AA, Baniel A, Kraberger S, Regney M, Harrach B, Kaján GL, Lu A, Beehner JC, Bergman TJ, Snyder-Mackler N, Varsani A, Schneider-Crease IA.   +12 more
europepmc   +1 more source

Lack of association between vaccine‐induced immune thrombocytopenia and thrombosis and HLA loci in a large cohort

British Journal of Haematology, EarlyView.
Linda Schönborn, Ana Tzvetkova, Thomas Thiele, Uwe Völker, Sabine Ameling, Sören Franzenburg, Lars Kaderali, Andreas Greinacher   +7 more
wiley   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

African swine fever virus genes vectored by simian adenoviruses do not protect against virulent genotype II virus challenge. [PDF]

Microbiol Spectr
Tng PYL, Al-Adwani L, Goatley LC, Loundras E-A, Powers C, Netherton CL.   +5 more
europepmc   +1 more source

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

The FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova, Caroline M. Ferreira, Katrina P. Montales, Francisco Villalobos, Alexandra J. Brownstein, Rebeca Acín‐Pérez, Gabrielly S. Ferreira, Anthony E. Jones, Linsey Stiles, Ajit S. Divakaruni, Marc Liesa, Orian S. Shirihai, Marcus F. Oliveira   +12 more
wiley   +1 more source

Nationwide Genomic Surveillance of Human Respiratory Adenoviruses in 2023-2024: Evidence of Extensive Diversity and Recombination in Russia. [PDF]

Viruses
Yolshin ND, Ivanova AA, Perederiy AA, Amosova IV, Timoshicheva TA, Stolyarov KA, Danilenko DM, Lioznov DA, Komissarov AB.   +8 more
europepmc   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Seasonal dynamics and genetic diversity of human adenoviruses in patients with acute respiratory infection in Thailand, 2024. [PDF]

PLoS One
Puenpa J, Tantipraphat L, Aeemjinda R, Vichaiwattana P, Korkong S, Poovorawan Y.   +5 more
europepmc   +1 more source