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Construction of Soluble Adenylyl Cyclase from Human Membrane-Bound Type 7 Adenylyl Cyclase
2002Adenylyl cyclase is the sole enzyme to synthesize cyclic AMP (cAMP), a key, second messenger that regulates diverse physiological responses including sugar and lipid metabolism, olfaction, and cell growth and differentiation. Most adenylyl cyclase activity in mammalian tissues is found in plasma membrane preparations with the exception of the ...
Shui-Zhong, Yan, Wei-Jen, Tang
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Molecular analysis of mammalian adenylyl cyclases and bacterial adenylyl cyclase toxins
2009Die Bildung des Second Messengers cAMP durch Adenylylcyclasen (AC) ist von essentieller Bedeutung in Zusammenhang mit vielen physiologischen Prozessen und Krankheitszuständen wie zum Beispiel neurodegenerativen Erkrankungen, Depression, Schmerz, Drogenabhängigkeit und Herzinsuffizienz.
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Ca2+-sensitive adenylyl cyclases
Cellular Signalling, 1994Cooper, Dermot M.F. +2 more
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