Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP
mBio, 2020 Antibiotic acyldepsipeptides (ADEPs) deregulate ClpP, the proteolytic core of the bacterial Clp protease, thereby inhibiting its native functions and concomitantly activating it for uncontrolled proteolysis of nonnative substrates.
Nadine Silber +5 more
doaj +2 more sources
Sensing and Bio-Sensing Research, 2016 Conventional dielectrophoresis (DEP) force on cell and particle is altered in the proximity of the electrodes due to the failure of the dipole approximation. In these conditions an anomalous DEP (aDEP) force rules the particle manipulation.
Antonino Magliano +11 more
doaj +2 more sources
Catalytic performance of surface modified-niobic acid
MATEC Web of Conferences, 2018 Surface modification of niobic acid with phosphoric acid and its catalytic performance in the hydrolysis reaction has been studied. A series of catalysts, surface-modified with different concentration of phosphoric acid, have been prepared and ...
Dwiatmoko Adid Adep
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Preparation and Characterization of pH-sensitive Doxorubicin Grafted Hyaluronic Acid Nano-micelles
International Journal of Medical Toxicology and Forensic MedicineBackground: This study was done to achieve a new drug delivery system delivering two different chemotherapy molecules to the target tissue simultaneously.
Babak Tajani +3 more
doaj +5 more sources
Coordination-Driven Orthogonal Ligand Pairings through Dual Hydrogen-Bonding/π-π Interaction Complementarity. [PDF]
ChemistryA series of bidentate ligands for square‐planar Pd(II) complexes were developed, each with hydrogen‐bonding and π‐π‐stacking domains that are complementary to only one other ligand. The bis‐bidentate complexes form orthogonally to one another with high fidelity, but only when both interaction types are exploited in tandem.
Smith JN +4 more
europepmc +2 more sources
Degradation of Nonribosomal Peptide Synthetase Megasynthetases SrfAA and SrfAB by Acyldepsipeptide-Activated ClpP in Bacillus Subtilis. [PDF]
ChembiochemFtsZ is the only target protein that has been biochemically confirmed to be hydrolyzed both in vitro and in bacterial cells. Coupled with activity‐based protein profiling of nonribosomal peptide synthetases, the ClpP‐ADEP1 proteolytic complex that degrades the surfactin synthetases SrfAA and SrfAB in cell lysates and bacterial cells is demonstrated ...
Ishikawa F +4 more
europepmc +2 more sources
Progression of the late-stage divisome is unaffected by the depletion of the cytoplasmic FtsZ pool
Communications Biology, 2021 Silber, Mayer, and colleagues examine how the depletion of the cytoplasmic FtsZ pool, triggered by ADEP antibiotics, affects the different stages of divisome formation and progression in Bacillus subtilis.
Nadine Silber +3 more
doaj +1 more source
Pillaring of bentonite clay with Zr, Ti, and Ti/Zr by ultrasonic technique for biodiesel production
South African Journal of Chemical Engineering, 2023 The current study concentrated on employing metal pillared bentonite catalysts to transform waste cooking oil. The goal of this research was to create pillared bentonite catalyst for effective low temperature conversion. The ultrasonic technique was used
Egi Agustian +3 more
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RESPONSE TO β-PRO DIETARY SUPPLEMENTATION IN GROWING RABBITS REARED AT DIFFERENT STOCKING DENSITIES UNDER HOT ENVIRONMENTAL CONDITIONS [PDF]
Egyptian Poultry Science, 2019 The current study was conducted to investigate the effect of β-Pro (probiotic-enzymes preparation) supplementation to 54 weaned rabbits (6-week-old with an average weight of 600 g) stocked at different stocking densities on some growth performance traits,
sara sherif +2 more
doaj +1 more source
Water Science and Technology, 2021 Several studies have detected SARS-CoV-2 in the stool of infected people as in urban wastewater. The quantification of SARS-CoV-2 in wastewater appears today as a powerful tool that can help in wastewater-based epidemiology (WBE).
F. Cutrupi +3 more
doaj +1 more source