Results 61 to 70 of about 230,428 (260)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Combined effects of fruit and vegetables intake and physical activity on the risk of metabolic syndrome among Chinese adults.

PLoS ONE, 2017
BackgroundUnbalanced dietary intake and insufficient physical activity (PA) have been recognized as risk factors for metabolic syndrome (MetS). We aimed to examine the independent and combined effects of fruit and vegetables (FV) intake and PA on MetS ...
Xin-Tong Li, Wei Liao, Hong-Jie Yu, Ming-Wei Liu, Shuai Yuan, Bo-Wen Tang, Xu-Hao Yang, Yong Song, Yao Huang, Shi-le Cheng, Zhi-Yu Chen, Samuel D Towne, Zong-Fu Mao, Qi-Qiang He   +13 more
doaj   +1 more source

Is iodine intake adequate in Norway?

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2019
In 2016, the Norwegian National Nutrition Council concluded that inadequate iodine intake is widespread in sections of the Norwegian population, and that effective measures should be undertaken immediately. This literature review aims to summarise articles published since January 2016 that describe the iodine intake in Norway.Literature searches were ...
Sigrun, Henjum, Marianne Hope, Abel, Helle Margrete, Meltzer, Lisbeth, Dahl, Jan, Alexander, Liv Elin, Torheim, Anne Lise, Brantsæter   +6 more
openaire   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Obesity coexists with malnutrition?: adequacy of food consumption by severely obese patients to dietary reference intake recommendations

Nutrición Hospitalaria, 2014
To assess the adequacy of food intake in severely obese patients and describe their main nutritional deficiencies on the basis of Dietary Reference Intakes (DRIs).
Jaqueline Driemeyer Correia Horvath, Mariana Laitano Dias de Castro, Natália Kops, Natasha Kruger Malinoski, Rogério Friedman   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

How to Monitor and Advise Vegans to Ensure Adequate Nutrient Intake

Journal of Osteopathic Medicine, 2016
Plant foods contain a negligible amount of vitamin B12; thus, vegans have difficulty meeting the recommended daily allowance (2.4 μg) and maintaining adequate serum concentrations of B12. In a cross-sectional study of 689 men, 121 of 232 vegans (52%) were B12 deficient (
Heather, Fields, Barbara, Ruddy, Mark R, Wallace, Amit, Shah, Denise, Millstine, Lisa, Marks   +5 more
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Analysis of Chinese adult residents receiving healthy lifestyle advice from medical institutions

Zhongguo gonggong weisheng
ObjectiveTo understand the status of Chinese adult residents receiving healthy lifestyle advice from medical institutions and to provide evidence for promoting healthy lifestyles in China. MethodsData were collected from 170 208 residents aged ≥ 18 years
Huiyan SUN, Limin WANG, Chun LI, Xiao ZHANG, Zhenping ZHAO, Mei ZHANG   +5 more
doaj   +1 more source