Results 61 to 70 of about 228,887 (260)

Marginal Micronutrient Intake in High-Performance Male Wheelchair Basketball Players: A Dietary Evaluation and the Effects of Nutritional Advice.

PLoS ONE, 2016
Wheelchair basketball has evolved into a high-performance sport over several years, and small variations in player performance can determine the difference between winning and losing. Therefore, adequate micronutrient intake may influence this difference
Lena Grams, Guadalupe Garrido, Jorge Villacieros, Amelia Ferro   +3 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Combined effects of fruit and vegetables intake and physical activity on the risk of metabolic syndrome among Chinese adults.

PLoS ONE, 2017
BackgroundUnbalanced dietary intake and insufficient physical activity (PA) have been recognized as risk factors for metabolic syndrome (MetS). We aimed to examine the independent and combined effects of fruit and vegetables (FV) intake and PA on MetS ...
Xin-Tong Li, Wei Liao, Hong-Jie Yu, Ming-Wei Liu, Shuai Yuan, Bo-Wen Tang, Xu-Hao Yang, Yong Song, Yao Huang, Shi-le Cheng, Zhi-Yu Chen, Samuel D Towne, Zong-Fu Mao, Qi-Qiang He   +13 more
doaj   +1 more source

Obesity coexists with malnutrition?: adequacy of food consumption by severely obese patients to dietary reference intake recommendations

Nutrición Hospitalaria, 2014
To assess the adequacy of food intake in severely obese patients and describe their main nutritional deficiencies on the basis of Dietary Reference Intakes (DRIs).
Jaqueline Driemeyer Correia Horvath, Mariana Laitano Dias de Castro, Natália Kops, Natasha Kruger Malinoski, Rogério Friedman   +4 more
doaj   +1 more source

How to Monitor and Advise Vegans to Ensure Adequate Nutrient Intake

Journal of Osteopathic Medicine, 2016
Plant foods contain a negligible amount of vitamin B12; thus, vegans have difficulty meeting the recommended daily allowance (2.4 μg) and maintaining adequate serum concentrations of B12. In a cross-sectional study of 689 men, 121 of 232 vegans (52%) were B12 deficient (
Heather, Fields, Barbara, Ruddy, Mark R, Wallace, Amit, Shah, Denise, Millstine, Lisa, Marks   +5 more
openaire   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Pressure ulcer healing promoted by adequate protein intake in rats

Experimental and Therapeutic Medicine, 2018
The effect of protein intake on rat pressure ulcer healing was evaluated. One hundred rats were numbered according to body weight and then they were randomly divided into 4 groups (n=25) using the random number table. After rat models of stage II pressure ulcer were established, they were fed with feed containing different protein levels (10, 15, 20 ...
Qin, Zhanfen, Wang, Yao, Zhao, Wei, Zhang, Yanan, Tian, Yiqing, Sun, Sujuan, Li, Xian   +6 more
openaire   +2 more sources