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Carbohydrate Receptors of Bacterial Adhesins: Implications and Reflections
2008Bacteria entering a host depend on adhesins to achieve colonization. Adhesins are bacterial surface structures mediating binding to host surficial areas. Most adhesins are composed of one or several proteins. Usually a single bacterial strain is able to express various adhesins.
K, Ohlsen +3 more
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Bacterial adhesins/glycolipid receptors
Current Opinion in Structural Biology, 1992Abstract Recognition of lipid-bound carbohydrate is a common motif in bacterial host cell binding. Although carbohydrate sequence determines binding affinity, an appreciation of other factors within the glycolipid or its molecular environment, which can affect the availability of recognized epitopes, is becoming evident.
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The Application of NMR Techniques to Bacterial Adhesins
2011Extracellular adhesins frequently compose large, highly-ordered structural assemblies that project away from the bacterial surface. These assemblies, known as pili or fimbriae, are rod-like polymeric structures that in some cases can extend up to several micrometers from the cell surface.
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Bacterial Adhesins: Determinants of Microbial Colonization and Pathogenicity
Advances in Pediatrics, 1997Bacterial adhesins are a critical determinant of microbial colonization and are fundamental to disease pathogenesis. In this chapter, I have reviewed certain paradigms that exist with respect to structure, variation of expression, and biologic activity.
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Characterization of Lectins and Bacterial Adhesins in Activated Sludge Flocs
Proceedings of the Water Environment Federation, 2008Bacterial lectins are carbohydrate‐binding proteins that are involved in bacterial adhesion and aggregation. To investigate whether lectins are involved in floc formation of activated sludge, hemaaggultination (HA) and HA inhibition assays were conducted on extracellular polymeric substances (EPS) extracted from activated sludges. Six sludges from both
Park, C, Novak, JT
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Gonococcal lipooligosaccharide: an adhesin for bacterial dissemination? Response
Trends in Microbiology, 2000Dr Nassif discusses gonococcal lipooligosaccharide (LOS) and its role as an adhesin in bacterial dissemination. Our laboratory has shown that, in HepG2 cells and sperm cells, the terminal lactosamine present on lacto-N-neotetraose-terminal gonococcal LOS is a ligand for the human asialoglycoprotein receptor (ASGP-R) 1.xNeisseria gonorrhoeae utilizes ...
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Chapter 25. Bacterial Adhesins
1991Publisher Summary Adhesins are proteins located on the surface of the bacteria that mediate their attachment to specific substrates as a prelude to colonization. Substrates may be inanimate surfaces, eukaryotic cells, or other bacteria. The relatively specific nature of adhesin interactions differentiates their mode of action from other surface ...
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Sticky Fibers and Uropathogenesis: Bacterial Adhesins in the Urinary Tract
Future Microbiology, 2006Adhesins mediate the introduction of bacteria to the host in the sometimes life-long relationship of uropathogenic Esherichia coli (UPEC) and the human urinary tract. As a class of extracellular proteins, adhesins enable bacteria to adhere to and, in some cases, invade host tissue; adhesins render UPEC virulent and permit host colonization.
Kelly J, Wright, Scott J, Hultgren
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Carbohydrates as recognition molecules for bacterial adhesins: Methodology and characteristics
Archives of Oral Biology, 1990Future attempts at developing inhibitors of dental plaque formation necessitate characterization of the bacterial-host, as well as the inter-bacterial recognition processes. Bacterial binding to a panel of solid-phase reference glycolipids was used to reveal the recognition of internal receptor sequences, low-affinity cooperative interactions, and ...
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