Results 31 to 40 of about 1,307,359 (192)

Adhesive polypeptides of Staphylococcus aureus identified using a novel secretion library technique in Escherichia coli

BMC Microbiology, 2011
Background Bacterial adhesive proteins, called adhesins, are frequently the decisive factor in initiation of a bacterial infection. Characterization of such molecules is crucial for the understanding of bacterial pathogenesis, design of vaccines and ...
Holm Liisa, Kankainen Matti, Kylväjä Riikka, Westerlund-Wikström Benita   +3 more
doaj   +1 more source

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

Journal of Experimental Medicine, 2017
Streptococcus pneumoniae is the main cause of bacterial meningitis, a life-threating disease with a high case fatality rate despite treatment with antibiotics.
F. Iovino, Joo-Yeon Engelen-Lee, M. Brouwer, D. van de Beek, A. van der Ende, M. Valls Seron, P. Mellroth, S. Muschiol, Jan Bergstrand, J. Widengren, B. Henriques‐Normark   +10 more
semanticscholar   +1 more source

Large-Scale Discovery of Microbial Fibrillar Adhesins and Identification of Novel Members of Adhesive Domain Families

bioRxiv, 2021
Fibrillar adhesins are a class of bacterial cell surface proteins that enable bacteria to interact with their environment. We developed a machine learning approach to identify fibrillar adhesins and applied this classification approach to the Firmicutes ...
Vivian A Monzon, A. Bateman
semanticscholar   +1 more source

Evaluation of cell binding activities of Leptospira ECM adhesins. [PDF]

PLoS Neglected Tropical Diseases, 2015
Pathogenic spirochetes of the genus Leptospira are the causative agents of leptospirosis, a zoonotic infection that occurs globally. The bacteria colonize the renal proximal tubules of many animals and are shed in the urine.
Gregory T Robbins, Beth L Hahn, Karen V Evangelista, Lavinia Padmore, Patrick S Aranda, Jenifer Coburn   +5 more
doaj   +1 more source

Rapid Aggregation of Staphylococcus aureus in Synovial Fluid Is Influenced by Synovial Fluid Concentration, Viscosity, and Fluid Dynamics, with Evidence of Polymer Bridging

mBio, 2022
Early bacterial survival in the postsurgical joint is still a mystery. Recently, synovial fluid-induced aggregation was proposed as a potential mechanism of bacterial protection upon entry into the joint. As synovial fluid is secreted back into the joint
Amelia Staats, Peter W. Burback, Andrew Schwieters, Daniel Li, Anne Sullivan, Alexander R. Horswill, Paul Stoodley   +6 more
doaj   +1 more source

Fatal Attraction: How Bacterial Adhesins Affect Host Signaling and What We Can Learn from Them

International Journal of Molecular Sciences, 2015
The ability of bacterial species to colonize and infect host organisms is critically dependent upon their capacity to adhere to cellular surfaces of the host.
D. Stones, A. Krachler
semanticscholar   +1 more source

The BtaF trimeric autotransporter of Brucella suis is involved in attachment to various surfaces, resistance to serum and virulence. [PDF]

PLoS ONE, 2013
The adhesion of bacterial pathogens to host cells is an event that determines infection, and ultimately invasion and intracellular multiplication. Several evidences have recently shown that this rule is also truth for the intracellular pathogen Brucella.
Verónica Ruiz-Ranwez, Diana M Posadas, Silvia M Estein, Patricia L Abdian, Fernando A Martin, Angeles Zorreguieta   +5 more
doaj   +1 more source

Adhesion of Helicobacter Species to the Human Gastric Mucosa: A Deep Look Into Glycans Role

Frontiers in Molecular Biosciences, 2021
Helicobacter species infections may be associated with the development of gastric disorders, such as gastritis, peptic ulcers, intestinal metaplasia, dysplasia and gastric carcinoma.
Rita Matos, Rita Matos, Rita Matos, Irina Amorim, Irina Amorim, Irina Amorim, Ana Magalhães, Ana Magalhães, Freddy Haesebrouck, Fátima Gärtner, Fátima Gärtner, Celso A. Reis, Celso A. Reis, Celso A. Reis, Celso A. Reis   +14 more
doaj   +1 more source

Localization of adhesins on the surface of a pathogenic bacterial envelope through atomic force microscopy.

Nanoscale, 2015
Bacterial adhesion is the first and a significant step in establishing infection. This adhesion normally occurs in the presence of flow of fluids. Therefore, bacterial adhesins must be able to provide high strength interactions with their target surface ...
L. Arnal, G. Longo, P. Stupar, M. F. Castez, Natalia Cattelan, R. Salvarezza, Osvaldo Yantorno, S. Kasas, M. E. Vela   +8 more
semanticscholar   +1 more source

Catch-bond mechanism of the bacterial adhesin FimH [PDF]

Nature Communications, 2016
AbstractLigand–receptor interactions that are reinforced by mechanical stress, so-called catch-bonds, play a major role in cell–cell adhesion. They critically contribute to widespread urinary tract infections by pathogenic Escherichia coli strains. These pathogens attach to host epithelia via the adhesin FimH, a two-domain protein at the tip of type I ...
Sauer, Maximilian M., Jakob, Roman P., Eras, Jonathan, Baday, Sefer, Eris, Deniz, Navarra, Giulio, Bernèche, Simon, Ernst, Beat, Maier, Timm, Glockshuber, Rudi   +9 more
openaire   +6 more sources