Results 51 to 60 of about 1,307,359 (192)
FimH and Anti-Adhesive Therapeutics: A Disarming Strategy Against Uropathogens
Antibiotics, 2020 Chaperone-usher fimbrial adhesins are powerful weapons against the uropathogens that allow the establishment of urinary tract infections (UTIs). As the antibiotic therapeutic strategy has become less effective in the treatment of uropathogen-related UTIs,
Meysam Sarshar +5 more
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adhesiomeR: a tool for Escherichia coli adhesin classification and analysis
BMC GenomicsAdhesins are crucial factors in the virulence of bacterial pathogens such as Escherichia coli. However, to date no resources have been dedicated to the detailed analysis of E. coli adhesins.
Katarzyna Sidorczuk +7 more
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Scientific Reports, 2017 Treponema pallidum subsp. pallidum, the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate throughout the body.
Wei-Chien Andrew Kao +12 more
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Stuck in the Middle: Fibronectin-Binding Proteins in Gram-Positive Bacteria
Frontiers in Microbiology, 2016 Fibronectin is a multidomain glycoprotein found ubiquitously in human body fluids and extracellular matrices of a variety of cell types from all human tissues and organs, including intestinal epithelial cells.
jeffrey Hymes, Todd Klaenhammer
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New Microbes and New Infections, 2019 Bacterial adhesins mediate the attachment and biofilm production leading to the persistence of colonized strains. The aim of this study was evaluation of the association of surface adhesin genes with the biofilm formation among Klebsiella oxytoca ...
A. Ghasemian +3 more
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Inhibition of Pathogen Adhesion by Bacterial Outer Membrane-Coated Nanoparticles.
Angewandte Chemie, 2019 The treatment of bacterial infection is increasingly challenged by the rapid emergence of antibiotic resistance. Among various alternatives, anti-adhesion therapies that interfere with the bacterial adhesion to the host are attractive, as they avoid ...
Yue Zhang +11 more
semanticscholar +1 more source
Nature Communications, 2010 Although soluble inhibitors are frequently used to block cell binding to the extracellular matrix (ECM), mechanical stretching of a protein fibre alone can physically destroy a cell-binding site.
M. Chabria +3 more
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Adhesion and host cell modulation: critical pathogenicity determinants of
Parasites & Vectors, 2011 Bartonella henselae, the agent of cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and peliosis hepatis, contains to date two groups of described pathogenicity factors: adhesins and type IV secretion systems.
Kempf Volkhard AJ, Franz Bettina
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A Review of the Mechanisms of Bacterial Colonization of the Mammal Gut
MicroorganismsA healthy animal intestine hosts a diverse population of bacteria in a symbiotic relationship. These bacteria utilize nutrients in the host’s intestinal environment for growth and reproduction.
Qingjie Lin +5 more
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Nature Communications, 2017 The mucus layer is an important physical niche within the gut which harbours a distinct microbial community. Here the authors show that specific carbohydrate-binding modules associated with bacterial carbohydrate-active enzymes are mucus adhesins that ...
C. David Owen +17 more
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