Results 51 to 60 of about 893,418 (338)

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in the Regulation of Immune Homeostasis in Sepsis-Mediated Lung Inflammation

Diagnostics, 2020
Septic shock/severe sepsis is a deregulated host immune system response to infection that leads to life-threatening organ dysfunction. Lung inflammation as a form of acute lung injury (ALI) is often induced in septic shock.
Yuichi Akama, Naoko Satoh-Takayama, Eiji Kawamoto, Atsushi Ito, Arong Gaowa, Eun Jeong Park, Hiroshi Imai, Motomu Shimaoka   +7 more
doaj   +1 more source

Investigations on the energy balance in TDCB tests [PDF]

Olaf Hesebeck, Udo Meyer, Andrea Sondag, Markus Brede, Investigations on the energy balance in TDCB tests, International Journal of Adhesion and Adhesives, Volume 67, June 2016, Pages 94-102, ISSN 0143-7496, 2015
The TDCB test is an established method to determine the critical strain energy release rate of adhesives in mode I. Provided that the adherends stay elastic, that the adhesive layer is not too flexible and that inertia effects can be neglected, the experiment allows to identify the work required by the adhesive layer per area of crack growth.
arxiv   +1 more source

Adhesion and Cohesion [PDF]

International Journal of Dentistry, 2012
The phenomena of adhesion and cohesion are reviewed and discussed with particular reference to dentistry. This review considers the forces involved in cohesion and adhesion together with the mechanisms of adhesion and the underlying molecular processes involved in bonding of dissimilar materials. The forces involved in surface tension, surface wetting,
openaire   +4 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Irisin promotes intestinal epithelial cell proliferation via Wnt/β-catenin and focal adhesion kinase signaling pathways

Scientific Reports
The regeneration of epithelia is crucial for maintaining intestinal homeostasis. Irisin is an exercise-induced hormone originally found to be secreted by skeletal muscles, thereby regulating energy metabolism.
Arong Gaowa, Supasuta Leangpanich, Eun Jeong Park, Eiji Kawamoto, Motomu Shimaoka   +4 more
doaj   +1 more source

Is There a Need for a More Precise Description of Biomolecule Interactions to Understand Cell Function?

Current Issues in Molecular Biology, 2022
An important goal of biological research is to explain and hopefully predict cell behavior from the molecular properties of cellular components. Accordingly, much work was done to build extensive “omic” datasets and develop theoretical methods, including
Pierre Bongrand
doaj   +1 more source

Adhesion of vesicles

Physical Review A, 1990
A simple model for the adhesion of vesicles to interfaces and membranes is introduced and theoretically studied. It is shown that adhering (or bound) vesicles can exhibit a large variety of different shapes. The notion of a contact angle governed by tension is found to be applicable only for a restricted subset of these shapes. Furthermore, the vesicle
Udo Seifert, Udo Seifert, Reinhard Lipowsky, Reinhard Lipowsky   +3 more
openaire   +5 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1

Communications Biology, 2023
Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation.
Eva-Maria Thüring, Christian Hartmann, Janesha C. Maddumage, Airah Javorsky, Birgitta E. Michels, Volker Gerke, Lawrence Banks, Patrick O. Humbert, Marc Kvansakul, Klaus Ebnet   +9 more
doaj   +1 more source