Results 51 to 60 of about 2,324,065 (396)

Biomimetic emulsions reveal the effect of homeostatic pressure on cell-cell adhesion

open access: yes, 2012
Cell-cell contacts in tissues are continuously subject to mechanical forces due to homeostatic pressure and active cytoskeleton dynamics. While much is known about the molecular pathways of adhesion, the role of mechanics is less well understood.
Brujic, Jasna   +3 more
core   +1 more source

Tenomodulin expression in the periodontal ligament enhances cellular adhesion. [PDF]

open access: yes, 2013
Tenomodulin (Tnmd) is a type II transmembrane protein characteristically expressed in dense connective tissues such as tendons and ligaments. Its expression in the periodontal ligament (PDL) has also been demonstrated, though the timing and function ...
Chung, Ung-Il   +10 more
core   +3 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

The Usefulness of Bone Biomarkers for Monitoring Treatment Disease: A Comparative Study in Osteolytic and Osteosclerotic Bone Metastasis Models

open access: yesTranslational Oncology, 2017
BACKGROUND: The skeleton is the most common site of colonization by metastatic cancers. Zoledronic acid (ZA) has been shown to be effective for the treatment of bone metastases regardless of whether the bone lesions are osteolytic or osteoblastic ...
Marta Martín-Fernández   +6 more
doaj   +1 more source

Adhesion-Induced Lateral Phase Separation in Membranes [PDF]

open access: yes, 2000
Adhesion between membranes is studied using a phenomenological model, where the inter-membrane distance is coupled to the concentration of sticker molecules on the membranes.
Andelman, David, Komura, Shigeyuki
core   +2 more sources

The Chemistry behind Catechol-Based Adhesion.

open access: yesAngewandte Chemie, 2018
The adhesion of some marine organisms to almost any kind of surface in wet conditions has aroused increasing interest in recent decades. Numerous fundamental studies have been performed to understand the scientific basis of this behaviour, with catechols
J. Saiz-Poseu   +4 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Identification of a membrane-less compartment regulating invadosome function and motility

open access: yesScientific Reports, 2018
Depletion of liprin-α1, ERC1 or LL5 scaffolds inhibits extracellular matrix degradation by invasive cells. These proteins co-accumulate near invadosomes in NIH-Src cells, identifying a novel invadosome–associated compartment distinct from the core and ...
Kristyna Sala   +4 more
doaj   +1 more source

Peritoneal adhesions after laparoscopic gastrointestinal surgery [PDF]

open access: yes, 2014
Although laparoscopy has the potential to reduce peritoneal trauma and post-operative peritoneal adhesion formation, only one randomized controlled trial and a few comparative retrospective clinical studies have addressed this issue.
MAIS, VALERIO
core   +1 more source

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