Results 141 to 150 of about 657,286 (284)

Activity of the lipoxygenase inhibitor 1-phenyl-3-pyrazolidinone (phenidone) and derivatives on the inhibition of adhesion molecule expression on human umbilical vascular endothelial cells

Biologics: Targets & Therapy, 2008
Torsten Hans Schroeder, Wolfgang Artur Krueger, Hans-Jürgen Dieterich, Boris NohéDepartment of Anaesthesiology and Critical Care Medicine, Tuebingen University Hospital, Tuebingen, GermanyAbstract: Leukocyte adhesion contributes to ...
Torsten Hans Schroeder, Wolfgang Artur Krueger, Hans-Jürgen Dieterich, Boris Nohé   +3 more
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Soluble mucosal addressin cell adhesion molecule 1 is a biomarker for pediatric ulcerative colitis. [PDF]

Mol Cell Pediatr
Muschaweck M, Gutbier C, Sellge G, Pappa A, Wenzl T, Hamesch K, Wagner N, Schippers A.   +7 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Neural Cell Adhesion Molecule Ncam1b Promotes Effective Hair Cell Regeneration in Zebrafish Neuromasts. [PDF]

Int J Mol Sci
Lange A, Dries R, Bastmeyer M, Bentrop J.   +3 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated. [PDF]

Oncol Lett
Mu Y, Sa N, Yu L, Lu S, Wang H, Xu W.
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Tumor Exosomal L1 Cell Adhesion Molecule Promotes Brain Metastasis of Lung Cancer. [PDF]

Research (Wash D C)
Kim DH, Lee CW, Choi YJ, Kim DS, Ban K, Hong J, Moon GJ, Kim SY, Pack CG, Baek IJ, Baek IJ, Jeong JY, Woo DC, Oh JH, Sung CO, Kim K, Kim HY, Jung HY, Ji W, Kim MJ, Choi CM, Lee JC, Rho JK.   +22 more
europepmc   +1 more source