Results 1 to 10 of about 85,816 (117)

ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo

Frontiers in Immunology, 2021
Neutrophil migration into the airways is an important process to fight infection and is mediated by cell adhesion molecules. The intercellular adhesion molecules, ICAM-1 (CD54) and ICAM-2 (CD102) are known ligands for the neutrophil integrins, lymphocyte
Deborah L W Chong, Ricardo J JOSÉ, Andrew E Williams   +2 more
exaly   +3 more sources

Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

Frontiers in Immunology, 2020
In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), myelin-specific T cells are activated in the periphery and differentiate in T helper (Th) 1 and Th17 effector cells, which cross the blood-brain barrier (BBB)
Luca Marchetti, Federica Moalli, Donovan Duc   +2 more
exaly   +3 more sources

Role of ICAM-1 in triple-negative breast cancer [PDF]

Open Medicine
Intercellular adhesion molecule-1 (ICAM-1) is related to the occurrence and development of a variety of tumors. However, the role of ICAM-1 in the regulation of growth, metastasis, and clinical prognosis of the specific molecular subtypes of breast ...
Zhang Ying, Fan Jingjing, Wang Xiaoli, Wu Zhongyu, Ma Weiqiang, Ma Binlin   +5 more
doaj   +2 more sources

Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium. [PDF]

PLoS ONE, 2010
BackgroundDuring transendothelial migration, leukocytes use adhesion molecules, such as ICAM-1, to adhere to the endothelium. ICAM-1 is a dynamic molecule that is localized in the apical membrane of the endothelium and clusters upon binding to leukocytes.
Jaap D van Buul, Jos van Rijssel, Floris P J van Alphen, Mark Hoogenboezem, Simon Tol, Kees A Hoeben, Jan van Marle, Erik P J Mul, Peter L Hordijk   +8 more
doaj   +1 more source

Vitamin E isoforms differentially regulate intercellular adhesion molecule-1 activation of PKCα in human microvascular endothelial cells. [PDF]

PLoS ONE, 2012
ICAM-1-dependent leukocyte recruitment in vivo is inhibited by the vitamin E isoform d-α-tocopherol and elevated by d-γ-tocopherol. ICAM-1 is reported to activate endothelial cell signals including protein kinase C (PKC), but the PKC isoform and the ...
Hiam Abdala-Valencia, Sergejs Berdnikovs, Joan M Cook-Mills   +2 more
doaj   +1 more source

Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response. [PDF]

PLoS ONE, 2013
We previously reported that leukocyte specific β2 integrins contribute to hypertrophy after muscle overload in mice. Because intercellular adhesion molecule-1 (ICAM-1) is an important ligand for β2 integrins, we examined ICAM-1 expression by murine ...
Christopher L Dearth, Qingnian Goh, Joseph S Marino, Peter A Cicinelli, Maria J Torres-Palsa, Philippe Pierre, Randall G Worth, Francis X Pizza   +7 more
doaj   +1 more source

ICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells

BMC Research Notes, 2018
Objective Regulation of intercellular adhesion molecule (ICAM)-1 in retinal endothelial cells is a promising druggable target for retinal vascular diseases.
Amanda L. Lumsden, Yuefang Ma, Liam M. Ashander, Andrew J. Stempel, Damien J. Keating, Justine R. Smith, Binoy Appukuttan   +6 more
doaj   +1 more source

Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria. [PDF]

PLoS ONE, 2013
Intercellular adhesion molecule 1 (ICAM-1) is a membrane-bound glycoprotein expressed on endothelial cells and cells of the immune system. Human ICAM-1 mediates adhesion and migration of leucocytes, and is implicated in inflammatory pathologies ...
Anja Bengtsson, Louise Joergensen, Zachary R Barbati, Alister Craig, Lars Hviid, Anja T R Jensen   +5 more
doaj   +1 more source

Intercellular adhesion molecule-1 expression and serum levels as markers of pre-clinical atherosclerosis in polycystic ovary syndrome

Journal of Ovarian Research, 2019
Background Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by obesity, hyperandrogenism, and insulin resistance.
Nearmeen M. Rashad, Amal S. El-Shal, Hala G. Abomandour, Amr Mostafa Kamel Aboelfath, Mohamed el sayed Rafeek, Mohammad Samir Badr, Ayman E. Ali, Mohammed S. Yousef, Maha Abdelhamid Fathy, Mustafa taha Abdelfattah Sharaf el din   +9 more
doaj   +1 more source

ICAM-1 and S100β plasma value in children with sepsis

Jurnal Profesi Medika, 2020
ICAM-1 release during sepsis is perceived to be related to brain injury. Whereas S100β  has been known as one of brain injury markers.To measure mean value of ICAM-1, S100β, to find correlation between ICAM-1 and Glasgow Coma Scale (GCS), between S100β ...
Lisa Safira, Anton H Pudjiadi, Sukman Tulus Putra   +2 more
doaj   +1 more source