Results 21 to 30 of about 85,965 (264)
Therapeutic Advances in Medical Oncology, 2019 Background: Leptin is considered a tumorigenic adipokine, suggested to promote tumorigenesis and progression in many cancers. On the other hand, intercellular adhesion molecule-1 (ICAM-1) shows altered expression in a variety of benign and malignant ...
Cheng-Fang Tsai +5 more
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ICAM‐1‐targeted nanocarriers attenuate endothelial release of soluble ICAM‐1, an inflammatory regulator [PDF]
Bioengineering & Translational Medicine, 2017 AbstractTargeting of drug nanocarriers (NCs) to intercellular adhesion molecule‐1 (ICAM‐1), an endothelial‐surface protein overexpressed in many pathologies, has shown promise for therapeutic delivery into and across this lining. However, due to the role of ICAM‐1 in inflammation, the effects of targeting this receptor need investigation.
Manthe, Rachel L., Muro, Silvia
openaire +2 more sources
Stem Cell Reports, 2018 Summary: The bone marrow niche plays a critical role in controlling the fate of hematopoietic stem cells (HSCs) by integrating intrinsic and extrinsic signals. However, the molecular events in the HSC niche remain to be investigated. Here, we report that
Yu-feng Liu +13 more
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Cell Death and Disease, 2022 Colorectal cancer (CRC) has a 5-year survival rate of
Eun-Ji Lim +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Breast tumors and their derived circulating cancer cells express the leukocyte β2 integrin ligand Intercellular adhesion molecule 1 (ICAM-1). We found that elevated ICAM-1 expression in breast cancer cells results in a favorable outcome and prolonged ...
Ofer Regev +14 more
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Assessment of ICAM-1 N-glycoforms in mouse and human models of endothelial dysfunction.
PLoS ONE, 2020 Endothelial dysfunction is a critical event in vascular inflammation characterized, in part, by elevated surface expression of adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1). ICAM-1 is heavily N-glycosylated, and like other surface
Kellie Regal-McDonald +8 more
doaj +1 more source
Characterization of the murine Icam-1 gene
Genomics, 1992 Intercellular adhesion molecule-1 (ICAM-1, CD54) is a cell adhesion molecule that interacts with the leukocyte beta 2 integrins, LFA-1 and Mac-1. Murine inflammatory models are being utilized increasingly to define the role that ICAM-1 induction plays in the initiation of inflammation. We have isolated murine genomic clones that contain the Icam-1 gene
C M, Ballantyne +3 more
openaire +2 more sources
World Electric Vehicle JournalThe worldwide commitment to the electrification of road transport will require a broad overhaul of equipment and infrastructure. Heavy-duty trucks account for over one-third of on-road energy use.
K. Darcovich +3 more
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A Knowledge‐Based Approach for Understanding and Managing Additive Manufacturing Data
Advanced Engineering Materials, EarlyView.Additive manufacturing processes generate a large amount of data. Effectively managing, understanding, and retrieving information from this data remains a major challenge. Therefore, we propose an ontology‐based approach to integrate heterogeneous data, enable semantic queries, and support decision‐making.
Mina Abd Nikooie Pour +5 more
wiley +1 more source
ADAM10-Mediated Cleavage of ICAM-1 Is Involved in Neutrophil Transendothelial Migration
Cells, 2021 To efficiently cross the endothelial barrier during inflammation, neutrophils first firmly adhere to the endothelial surface using the endothelial adhesion molecule ICAM-1. Upon actual transmigration, the release from ICAM-1 is required.
Sofia K. H. Morsing +5 more
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