Results 11 to 20 of about 21,323,950 (308)

Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response. [PDF]

PLoS ONE, 2013
We previously reported that leukocyte specific β2 integrins contribute to hypertrophy after muscle overload in mice. Because intercellular adhesion molecule-1 (ICAM-1) is an important ligand for β2 integrins, we examined ICAM-1 expression by murine ...
Christopher L Dearth, Qingnian Goh, Joseph S Marino, Peter A Cicinelli, Maria J Torres-Palsa, Philippe Pierre, Randall G Worth, Francis X Pizza   +7 more
doaj   +1 more source

ICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells

BMC Research Notes, 2018
Objective Regulation of intercellular adhesion molecule (ICAM)-1 in retinal endothelial cells is a promising druggable target for retinal vascular diseases.
Amanda L. Lumsden, Yuefang Ma, Liam M. Ashander, Andrew J. Stempel, Damien J. Keating, Justine R. Smith, Binoy Appukuttan   +6 more
doaj   +1 more source

Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

Frontiers in Immunology, 2020
In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), myelin-specific T cells are activated in the periphery and differentiate in T helper (Th) 1 and Th17 effector cells, which cross the blood-brain barrier (BBB)
Neda Haghayegh Jahromi, Luca Marchetti, Federica Moalli, Donovan Duc, Camilla Basso, Heidi Tardent, Elisa Kaba, Urban Deutsch, Caroline Pot, Federica Sallusto, Federica Sallusto, Jens V. Stein, Britta Engelhardt   +12 more
doaj   +1 more source

PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells [PDF]

, 2007
Interactions between leukocytes and vascular endothelial cells are mediated by a complex set of membrane adhesion molecules which transduce bi-directional signals in both cell types.
Laran-Chich, M.-P., Bourdoulous, S., Pierre-Olivier Couraud, John Greenwood, Leveque, M., Greenwood, J., Mathilde Leveque, Rampon, C., Couraud, P.-O., Jean-Pierre Couty, Christine Rampon, Marie-Pierre Laran-Chich, Couty, J.-P., Sandrine Bourdoulous   +13 more
core   +1 more source

ICAM G241A polymorphism and soluble ICAM-1 serum levels: Evidence for an active immune process in schizophrenia [PDF]

, 2005
Objectives: We have previously reported reduced serum levels of soluble intercellular adhesion molecule-1 (sICAM-1) in schizophrenic patients. A single-nucleotide polymorphism ( SNP) of the ICAM-1 gene was described at position 241.
Müller, Norbert, Kronig, H., Schwarz, Markus J., Strassnig, M., Ackenheil, Manfred, Möller, Hans-Jürgen, Riedel, M.   +6 more
core   +1 more source

The physiological roles of ICAM-1 and ICAM-2 in neutrophil migration into tissues [PDF]

, 2015
PURPOSE OF REVIEW Neutrophil extravasation from the blood into tissues is initiated by tethering and rolling of neutrophils on endothelial cells, followed by neutrophil integrin activation and shear resistant arrest, crawling, diapedesis and breaching
Gaby Enzmann, Lyck, Ruth, Enzmann, Gaby, Ruth Lyck   +3 more
core   +1 more source

Intercellular adhesion molecule-1 expression and serum levels as markers of pre-clinical atherosclerosis in polycystic ovary syndrome

Journal of Ovarian Research, 2019
Background Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by obesity, hyperandrogenism, and insulin resistance.
Nearmeen M. Rashad, Amal S. El-Shal, Hala G. Abomandour, Amr Mostafa Kamel Aboelfath, Mohamed el sayed Rafeek, Mohammad Samir Badr, Ayman E. Ali, Mohammed S. Yousef, Maha Abdelhamid Fathy, Mustafa taha Abdelfattah Sharaf el din   +9 more
doaj   +1 more source

ICAM-1 and CD11c co-localize during exosome-macrophage interactions. [PDF]

, 2018
(A) Immunoblotting analysis reveals exosomes from the pancreatic cancer cell lines AsPC-1 and BxPC-3 are enriched in the surface-exposed proteins ICAM-1 and EpCAM, while CD9 is more broadly expressed.
Todd Fox (2404426), Jason Liao (327300), Peter J. Butler (518044), Mark Kester (499862), Gary A. Clawson (315235), Samuel S. Linton (5921279), Gail L. Matters (782780), Thomas Abraham (121104)   +7 more
core   +1 more source

Hyperglycemia Decreases Epithelial Cell Proliferation and Attenuates Neutrophil Activity by Reducing ICAM-1 and LFA-1 Expression Levels

Frontiers in Genetics, 2020
Delayed repair is a serious public health concern for diabetic populations. Intercellular adhesion molecule 1 (ICAM-1) and Lymphocyte function-associated antigen 1 (LFA-1) play important roles in orchestrating the repair process. However, little is known
Dongxu Qiu, Lei Zhang, Junkun Zhan, Qiong Yang, Hongliang Xiong, Weitong Hu, Qiao Ji, Jiabing Huang   +7 more
doaj   +1 more source

Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria. [PDF]

PLoS ONE, 2013
Intercellular adhesion molecule 1 (ICAM-1) is a membrane-bound glycoprotein expressed on endothelial cells and cells of the immune system. Human ICAM-1 mediates adhesion and migration of leucocytes, and is implicated in inflammatory pathologies ...
Anja Bengtsson, Louise Joergensen, Zachary R Barbati, Alister Craig, Lars Hviid, Anja T R Jensen   +5 more
doaj   +1 more source