Vascular Cell Adhesion Molecule 1 in atrial fibrillation [PDF]
Objective Assessing whether serum Vascular Cell Adhesion Molecule 1(VCAM-1) concentration in the left atrial appendage(LAA) and the expression of VCAM-1 in LAA tissues are associated with the risk of atrial fibrillation-related stroke.
ZhiZhi Jiang +7 more
doaj +4 more sources
Liver sinusoidal endothelial cell expressed vascular cell adhesion molecule 1 promotes liver fibrosis [PDF]
BackgroundDuring liver injury, liver sinusoidal endothelial cells (LSECs) dysfunction and capillarization promote liver fibrosis. We have previously reported that the LSEC vascular cell adhesion molecule 1 (VCAM1) plays a key role in liver inflammation ...
Qianqian Guo +9 more
doaj +2 more sources
Targeting endothelial vascular cell adhesion molecule-1 in atherosclerosis: drug discovery and development of vascular cell adhesion molecule-1-directed novel therapeutics. [PDF]
Abstract Vascular cell adhesion molecule-1 (VCAM-1) has been well established as a critical contributor to atherosclerosis and consequently as an attractive therapeutic target for anti-atherosclerotic drug candidates. Many publications have demonstrated that disrupting the VCAM-1 function blocks monocyte infiltration into the sub ...
Pickett JR, Wu Y, Zacchi LF, Ta HT.
europepmc +3 more sources
Associations of Circulating Vascular Cell Adhesion Molecule‐1 and Intercellular Adhesion Molecule‐1 With Long‐Term Cardiac Function [PDF]
Background Although VCAM‐1 (vascular cell adhesion molecule‐1) and ICAM‐1 (intercellular adhesion molecule‐1) have been associated with incident heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF), the associations of VCAM‐
Daniel T. Mathew +7 more
doaj +2 more sources
Immunohistochemical Analysis of Adhesion Molecules E-Selectin, Intercellular Adhesion Molecule-1, and Vascular Cell Adhesion Molecule-1 in Inflammatory Lesions of Atopic Dermatitis [PDF]
E-selectin, ICAM-1 (intercellular adhesion molecule-1), and VCAM-1 (vascular cell adhesion molecule-1) play a role in atopic dermatitis (AD). This study aimed to evaluate their expression in skin biopsy specimens of patients diagnosed with AD using an ...
Sandra Marinović Kulišić +4 more
doaj +2 more sources
Comment on: Vascular cell adhesion molecule-1 in rheumatoid arthritis. [PDF]
Salem and Zahran[1][1] conducted a cross sectional study investigating the role of VCAM-1 in patients with rheumatoid arthritis (RA), its relation to disease activity, oxidative stress and systemic inflammation.[1][1] They studied 50 patients with early newly diagnosed RA (less than 6 month ...
Jawad AS.
europepmc +4 more sources
Two Novel PET Radiopharmaceuticals for Endothelial Vascular Cell Adhesion Molecule-1 (VCAM-1) Targeting [PDF]
Atherosclerosis is a chronic progressive disease involving inflammatory events, such as the overexpression of adhesion molecules including the endothelial Vascular Cell Adhesion Molecule-1 (VCAM-1).
Sara Pastorino +11 more
doaj +2 more sources
Puerarin attenuates the inflammatory response of vascular endothelial cells in KKAy mice [PDF]
Objective To explore the intervention mechanism of puerarin(PUR) on the inflammatory response of vascular endothelial cells with KKAy mouse models.Methods C57bL/6j mice were used as the control group.
ZOU Jie, ZHANG Dede, TAO Yi, ZHAO Jing, WANG Qiong, XU Naijia
doaj +1 more source
Serum concentration of soluble adhesive molecules in patients with different forms of coronary artery disease [PDF]
Background/Aim. Vascular cell adhesion molecules-1 (VCAM-1) and intercellular cell adhesive molecules-1 (ICAM- 1) play an important role in developing and progression of coronary atherosclerosis.
Damnjanović Goran +3 more
doaj +1 more source
Endothelial expression of intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 is suppressed by postbypass plasma containing increased soluble intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 [PDF]
Endothelial cell dysfunction has been implicated in the inflammatory response to cardiopulmonary bypass, and the upregulation of endothelial cell expression of adhesion molecules might promote leukocyte extravasation in vivo. Soluble endothelial cell adhesion molecules are increased after bypass.
Vallely, Michael P. +3 more
openaire +2 more sources

