Results 11 to 20 of about 289,601 (306)

Alterations in intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) in human endothelial cells

Tissue and Cell, 2018
Alterations of Endothelial cells (ECs) play a critical role in different pathogenesis of many serious human diseases, and dysfunction of the vascular endothelium is an indicator for human disorders. Endothelial dysfunction is considered to be an early indicator for atherosclerosis, which is characterised by overexpression of adhesion molecules ...
Khaled Habas, Lijun Shang
openaire   +6 more sources

Thioredoxin1 downregulates oxidized low-density lipoprotein-induced adhesion molecule expression via Smad3 protein. [PDF]

PLoS ONE, 2013
Atherosclerosis is a chronic inflammation disease that is initiated by endothelial cell injury. Oxidized low-density lipoprotein (ox-LDL) is directly associated with chronic vascular inflammation. To understand whether thioredoxin1 (Trx1) participates in
Beidong Chen, Wendong Wang, Tao Shen, Ruomei Qi   +3 more
doaj   +1 more source

Regulation of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 in human vascular smooth muscle cells. [PDF]

Circulation Research, 1994
Vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and E-selectin are inducible proteins involved in cell-cell adhesion. Immunohistochemical studies have indicated that human atherosclerotic plaques contain smooth muscle cells (SMCs) that express ICAM-1 and VCAM-1.
T, Couffinhal, C, Duplàa, C, Moreau, J M, Lamazière, J, Bonnet   +4 more
openaire   +2 more sources

Carbamylated Low-Density Lipoprotein Induces Monocyte Adhesion to Endothelial Cells Through Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
Objective—Carbamylated low-density lipoprotein (LDL), the most abundant modified LDL isoform in human blood, has been recently implicated in causing the atherosclerosis-prone injuries to endothelial cells in vitro and atherosclerosis in humans. This study was aimed at testing the hypothesis that carbamylated LDL acts via inducing monocyte adhesion to ...
Apostolov, Eugene O., Shah, Sudhir V., Ok, Ercan, Basnakian, Alexei G.   +3 more
openaire   +2 more sources

Association of endothelin-1 and cell surface adhesion molecules levels in patients with systemic sclerosis

Journal of Laboratory Medicine, 2020
Endothelin-1 (ET-1) has been implicated in the pathogenesis of inflammatory and fibrotic diseases, including systemic sclerosis. In addition to modulating vascular tone and extracellular matrix turnover, ET-1 up-regulates cell surface adhesion molecules ...
Mauliūtė Monika, Rugienė Rita, Žėkas Vytautas, Bagdonaitė Loreta   +3 more
doaj   +1 more source

Bleomycin increases neutrophil adhesion to human vascular endothelial cells independently of upregulation of ICAM-1 and E-selectin [PDF]

, 2016
© 2016 Taylor & Francis. Aim of the Study: Bleomycin-induced lung disease is a serious complication of therapy characterized by alveolar injury, cytokine release, inflammatory cell recruitment, and eventually pulmonary fibrosis.
Crooks, Michael G., Greenman, John, Hart, Simon P., Sadofsky, Laura R., Williamson, James D.   +4 more
core   +1 more source

Bilirubin Prevents Atherosclerotic Lesion Formation in Low‐Density Lipoprotein Receptor‐Deficient Mice by Inhibiting Endothelial VCAM‐1 and ICAM‐1 Signaling

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundNumerous epidemiological studies support an inverse association between serum bilirubin levels and the incidence of cardiovascular disease; however, the mechanism(s) by which bilirubin may protect against atherosclerosis is undefined. The goals
Megan E. Vogel, Gila Idelman, Eddy S. Konaniah, Stephen D. Zucker   +3 more
doaj   +1 more source

Intracellular Adhesion Molecule (ICAM-1), Vascular Cell Adhesion Molecule (VCAM-1) and E-selectin levels in first episode schizophrenic patients

Psychiatry and Clinical Psychopharmacology, 2021
Objectives: The aim of this study was to compare the levels of intracellular adhesion molecule (ICAM-1), vascular cell adhesion molecule (V-CAM-1) and E-selectin, which are considered as possible biological determinants in prognosis and progression of ...
Semine Ozdogan Kavzoglu, Aytul Gursu Hariri   +1 more
doaj   +1 more source

Effects of stereoisomers of thioctic acid on rat renal vasculature microanatomy [PDF]

, 2012
Metabolism of oxygen by cells can generate potentially dangerous reactive oxygen species (ROS). Endothelial cells lining vascular luminal surface are an important site of signalling molecules and a ROS target during ischemia, inflammation and other ...
AMENTA, Francesco, Nwankow, EI, Tavoletti, M, TAYEBATI, Seyed Khosrow, Zamponi, B   +4 more
core   +1 more source

Effects of Nigella sativa on VCAM-1 and ICAM-1: A systematic review of preclinical and clinical studies [PDF]

Journal of Cardiovascular and Thoracic Research
The objective of present review was to assess all studies about effect of Nigella sativa (N. sativa) on vascular cell and intercellular adhesion molecules-1 (VCAM-1 and ICAM-1) under different situations. Search was performed until May 2024 using Scopus,
Zeinab Faghfoori, Zeinab Javadivala, Aida Malek Mahdavi   +2 more
doaj   +1 more source