Results 41 to 50 of about 111,326 (300)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Jurnal Rekayasa Kimia & Lingkungan, 2020 The charcoal produced from oil palm empty fruit bunches’ pyrolysis can be utilised as environmentally friendly alternative fuel briquettes. This research studied the physical characteristics of EFB briquettes using brown algae as an adhesive.
Ana Dewita, M. Faisal, Asri Gani
doaj +1 more source
Fibers, 2022 Wood and its processing into particles are, combined, the largest cost factor in the production of particleboard, followed by the cost of adhesive. Thus, reducing their cost is a goal of process optimization.
Jan T. Benthien +4 more
doaj +1 more source
Yielding and flow in adhesive and non-adhesive concentrated emulsions
, 2006 The nonlinear rheological response of soft glassy materials is addressed experimentally by focusing on concentrated emulsions where interdroplet attraction is tuned through varying the surfactant content.
MANNEVILLE, S. +5 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2013 The effects of adhesive thickness, adhesive type and scarf angle, which are determined as the main control parameters by the dimensional analysis, on the mechanical properties of a scarf adhesive joint (SJ) subjected to uniaxial tensile loading are ...
Huang, Chenguang +2 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Synthesis and Experimental Characterization of a MWCNT-Filled Bio-Based Adhesive
Aerospace, 2021 In the present paper, a novel epichlorohydrin/cardanol adhesive was reinforced by multi-walled carbon nanotubes (MWCNTs) and characterized experimentally. The adhesive was reinforced by MWCNTs in weight ratios (wt %) of 0.5%, 1.0% and 2.0%.
Konstantinos Tserpes +1 more
doaj +1 more source