Results 61 to 70 of about 6,173,655 (285)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Fracture mechanics of adhesive joints

, 2022
S.135-166This chapter summarizes the basic principles and definitions of fracture mechanics and gives an overview of its application to adhesive bonding. From the macroscopic point of view the stress intensity factor or the equivalent energy release rate
Brede, Markus
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Effects of Water Immersion on the Adhesion between Adhesive Layer and Concrete Block

Advances in Civil Engineering, 2019
The effectiveness of load transfer in the CFRP-adhesive-concrete system highly relies on the integrity of the interfacial bond between adhesive layer and concrete.
Jiajun Shi, Yunfeng Pan, Hedong Li, Jun Fu   +3 more
doaj   +1 more source

Addition of kraft lignin of Eucalyptus sp. on the properties of the lignin-phenol-formaldehyde adhesive [PDF]

Ciência Rural
: The objective of this research was to extract lignin from Eucalyptus sp. kraft black liquor and to evaluate the influence of its addition on the properties of the lignin-phenol-formaldehyde adhesive.
Emerson Belarmino Costa, Adriana de Fátima Gomes Gouvêa, Adriano Olímpio da Silva, Gustavo Ruivo Salmazzo, Claudia Marcia Gomes, Armando Cirilo de Souza   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effect of Pyrolysis Temperature and Adhesive Type on the Quality of Biobriquette from Coffee Stem Biomass [PDF]

E3S Web of Conferences
Biobriquette is organic waste charcoal printed in such a way that has a high energy density and calorific value. The biobriquette quality is influenced by several factors, including the pyrolysis temperature and the adhesive type.
Hasibuan Rosdanelli, Hidayati Juliza, Misran Erni, Permata Sari Purba Intan, Erlangga Fauzan, Pramananda Viqry, Fahira Siregar Fatimah   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The Effect of Silane Content on Microleakage of the Adhesive Systems

Journal of International Dental Sciences, 2016
Aim: The aim of this study is to compare to microleakage levels of two silane based adhesive systems and one silane free adhesive system.Material and Method: Thirty standardized freshly extracted sound premolar teeth were used in study. Teeth were randomly and divided into three groups of 10 teeth each, according to the adhesive systems n=20 .
ÖZSEVİK, A. Semih, SÜRMELİOĞLU, Derya, TOSUN, Samet, BACAKSIZ, Burcu, ŞİRİN KARAARSLAN, Emine   +4 more
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source