Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
High throughput microbalance and methods of using same [PDF]
, 2007 The method and apparatus is particularly adapted for providing microbalance measurement of solid materials as part of a combinatorial research program.
Carlson, Eric +4 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Experimental determination of the effects of moisture on composite-to-composite adhesive joints [PDF]
The primary mode of moisture ingress into bonded composite joints is determined using a nuclear probe for deuterium (NPD) to measure the localized D2O content along the length of the adhesive (FM-300 and EA-9601) and through the thickness of bonded ...
Deiasi, R. J., Schulte, R. L.
core +1 more source
High throughput microbalance and methods of using same [PDF]
, 2005 A method and apparatus for measurement of mass of small sample sizes. The method and apparatus is particularly adapted for providing microbalance measurement of solid materials as part of a combinatorial research program.
Carlson, Eric, Kolosov, Oleg, Matsiev, L
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The effect of elevated temperature exposure on the fracture toughness of solid wood and structural wood composites [PDF]
, 2004 This is the author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Springer and can be found at: http://www.springer.com/life+sciences/forestry/journal/226.Fracture toughness of wood and wood ...
H.G. Direen +4 more
core +4 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Adhesion Properties between Polyvinyl Acetate Dispersion and Ammonia Modified Oak Wood
Medžiagotyra, 2013 It is known that PVA dispersion exhibits very good adhesion with natural wood. However, still remains unclear what adhesion-related changes occur, when the outside factor, i. e.
Darius MINELGA +3 more
doaj +1 more source
Loofah Sandwich Panels: The Effect of Adhesive Content on Mechanical and Physical Properties. [PDF]
Materials (Basel), 2022 Köhler R +4 more
europepmc +1 more source
Development of oriented strand board from acacia wood (Acacia mangium willd): effect of pretreatment of strand and adhesive content on the physical and mechanical properties of OSB. [PDF]
, 2009 Acacia wood (Acacia mangium Willd.) is the most popular fast growing tree species planted in timber estate in Indonesia and is considered to be very valuable raw materials for structural composite products.
Bakar, Edi Suhaimi +5 more
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