TLR4-dependant pro-inflammatory effects of HMGB1 on human adipocyte
Guerin-Dubourg, A +9 more
core +1 more source
Adipose-specific Kdm2a deficiency promotes ferroptosis-associated features and hypertrophic remodeling of adipocytes. [PDF]
Li A +10 more
europepmc +1 more source
IRF1 in Adipocytes Is Associated with Insulin Signaling and Mitochondrial Homeostasis in Diet-Induced Obesity. [PDF]
Zhu A, Zhou Y, Ren K, Sun C.
europepmc +1 more source
Aloe-Emodin Modifies Adipogenic Genes and the Expression of miR-143 and miR-155 in 3T3-L1 Cells. [PDF]
Torres-Estrella CU +5 more
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Multi‐omics–driven precision medicine
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
Exosome trafficking is a key regulator of adipocyte thermogenesis. [PDF]
Kesharwani D +11 more
europepmc +1 more source
Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber
This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu +9 more
wiley +1 more source
Hematopoietic-Specific DARC Deficiency Is Associated with Adipose Tissue Inflammation and Impaired Glucose Tolerance During Diet-Induced Obesity in Mice. [PDF]
Aboud G +26 more
europepmc +1 more source

