Adipose Tissue Expandability as a Link Between Nutrition and Obesity-Related Metabolic Risk: Insights from Bariatric Surgery. [PDF]
Jiménez-Flores E +9 more
europepmc +1 more source
Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal +2 more
wiley +1 more source
Persistent effects of pre-differentiation manganese exposure on adipogenesis and metabolic function in differentiated 3T3-L1 adipocyte cells. [PDF]
Malhi R +8 more
europepmc +1 more source
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi +15 more
wiley +1 more source
Adipose Tissue Remodeling Beyond Weight Loss: New Insights Into Incretin-Based Therapies and Bariatric Surgery. [PDF]
Abud GF, de Freitas EC, Stanford KI.
europepmc +1 more source
ABSTRACT Background Noninvasive quantitative assessment of marrow recovery after curative therapies such as total marrow irradiation (TMI) and bone marrow transplantation (BMT) remain poorly defined, particularly in sickle cell disease (SCD). Purpose To evaluate MRI‐derived proton density fat fraction (PDFF) as a biomarker of marrow recovery following ...
Malakeh Malekzadeh +12 more
wiley +1 more source
Lactational Enrofloxacin Exposure Promotes Offspring Lipid Metabolic Disorder and Adiposity Involving Gut Microbiota-Derived LPS and PPARγ Signaling. [PDF]
Li Y +6 more
europepmc +1 more source
ABSTRACT Background Proton density fat fraction (PDFF) is typically measured using confounder‐corrected, multi‐echo, gradient‐recalled‐echo chemical‐shift‐encoded (CSE)‐MRI. Ferumoxytol, an iron‐based MRI contrast agent, increases liver and bone marrow (BM) R2*, a major confounder of PDFF.
Lukas Müller +6 more
wiley +1 more source
Cancer-associated adipocytes: metabolic reprogramming, crosstalk and therapeutic implications in tumor progression. [PDF]
Shi J +5 more
europepmc +1 more source

