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Adipocytes

2003
There are several preadipocyte cell lines reported, but in this chapter, we will describe mainly the 3T3-L1 cells, which are best characterized and widely used for molecular biological studies. The 3T3-L1 cells were clonally isolated by Green and Kehinde from 3T3-Swiss albino.
S, Gamou, Y, Shimizu, N, Shimizu
openaire   +2 more sources

Pink Adipocytes

Trends in Endocrinology & Metabolism, 2018
Adipocytes are lipid-rich parenchymal cells contained in a very plastic organ, whose composition can undergo striking physiologic changes. In standard conditions the organ contains white and brown adipocytes which play opposite roles: lipid storage to meet metabolic requirements and lipid burning for thermogenesis, respectively.
openaire   +2 more sources

Understanding Adipocyte Differentiation

Physiological Reviews, 1998
Gregoire, Francine M., Cynthia M. Smas, and Hei Sook Sul. Understanding Adipocyte Differentiation. Physiol. Rev. 78: 783–809, 1998. — The adipocyte plays a critical role in energy balance. Adipose tissue growth involves an increase in adipocyte size and the formation of new adipocytes from precursor cells.
F M, Gregoire, C M, Smas, H S, Sul
exaly   +3 more sources

Genesis of adipocytes

Clinics in Dermatology, 1989
Abstract The origin of fat cells has been the subject of continuous debate. It was first suggested that the adipocyte was derived from an undifferentiated mesenchymal cell, a cell that besides giving rise to the adipocyte can also give rise to endothelium, and pericytes, 1,2 fibroblasts, chondroblasts, and osteoblasts, as well as mast cells and the ...
T J, Ryan, S B, Curri
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Adipocyte Mineralocorticoid Receptor

2019
Mineralocorticoid receptor (MR) has been recently identified in adipose tissue, where its excessive activation contributes to several metabolic derangements often observed in obesity and metabolic syndrome. Recent findings support the existence of a bidirectional cross-talk between adipose tissue and adrenal glands, contributing to obesity-related ...
Infante M.   +4 more
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[Leptin: adipocyte hormone].

Recenti progressi in medicina, 1998
The authors reviewed the most recent literature on leptin, a protein produced by adipocytes which exerts its action on hypothalamus, modifying eating behavior and inhibiting the lust for food consumption. This one appeared to be the main, if not the only, physiologic action of leptin.
CASTAGNA L   +8 more
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Adipocyte–Brain: Crosstalk

2010
The initial discovery of leptin, an appetite-suppressing hormone originating from fat tissue, substantially supported the idea that fat-borne factors act on the brain to regulate food intake and energy expenditure. Since then, a growing number of cytokines have been found to be released from adipose tissue, thus acting in an endocrine manner.
Carla, Schulz   +2 more
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Mechanotransduction in adipocytes

Journal of Biomechanics, 2012
Obesity is widely recognized as a major public health problem due to its strong association with a number of serious chronic diseases including hyperlipidemia, hypertension, type II diabetes and coronary atherosclerotic heart disease. During the development of obesity, the positive energy balance involves recruitment of new adipocytes from ...
Naama, Shoham, Amit, Gefen
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Human White Adipocytes Convert Into “Rainbow” Adipocytes In Vitro

Journal of Cellular Physiology, 2017
White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo. These plastic properties could be used in future for regenerative medicine, but are incompletely explored in their details.
Maurizi G   +17 more
openaire   +5 more sources

Hormonal Control of Adipocyte Differentiation and Adipocyte Gene Expression

1988
Publisher Summary This chapter presents a summarization of a large number of studies aimed at elucidating the signaling system by which determined cells decide to activate a terminal differentiation program. Using adipogenic cells in culture, it can be documented that the hormonal milieu plays a major role in dictating the decision to trigger ...
G M, Ringold   +4 more
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