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Archives of Pharmacal Research, 2020
White adipocytes play a key role in maintaining whole body energy homeostasis by forming white adipose tissue (WAT). The impairment of WAT formation or WAT dysfunction is clearly associated with severe metabolic disorders. Mature adipocytes are derived from differentiated preadipocytes and are pivotal in energy storage and metabolism.
Tianchang Gao +8 more
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White adipocytes play a key role in maintaining whole body energy homeostasis by forming white adipose tissue (WAT). The impairment of WAT formation or WAT dysfunction is clearly associated with severe metabolic disorders. Mature adipocytes are derived from differentiated preadipocytes and are pivotal in energy storage and metabolism.
Tianchang Gao +8 more
openaire +3 more sources
Clinics in Dermatology, 1989
Abstract The origin of fat cells has been the subject of continuous debate. It was first suggested that the adipocyte was derived from an undifferentiated mesenchymal cell, a cell that besides giving rise to the adipocyte can also give rise to endothelium, and pericytes, 1,2 fibroblasts, chondroblasts, and osteoblasts, as well as mast cells and the ...
Sergio B. Curri, Terence J. Ryan
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Abstract The origin of fat cells has been the subject of continuous debate. It was first suggested that the adipocyte was derived from an undifferentiated mesenchymal cell, a cell that besides giving rise to the adipocyte can also give rise to endothelium, and pericytes, 1,2 fibroblasts, chondroblasts, and osteoblasts, as well as mast cells and the ...
Sergio B. Curri, Terence J. Ryan
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Mechanotransduction in adipocytes
Journal of Biomechanics, 2012Obesity is widely recognized as a major public health problem due to its strong association with a number of serious chronic diseases including hyperlipidemia, hypertension, type II diabetes and coronary atherosclerotic heart disease. During the development of obesity, the positive energy balance involves recruitment of new adipocytes from ...
Amit Gefen, Naama Shoham
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Human White Adipocytes Convert Into “Rainbow” Adipocytes In Vitro
Journal of Cellular Physiology, 2017White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo. These plastic properties could be used in future for regenerative medicine, but are incompletely explored in their details.
Maurizi G +17 more
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2010
In mammals, the adipose organ is composed of white adipocytes (primary site in energy storage) and of brown adipocytes (specialized in thermogenesis). Adipocytes arise from mesenchymal stem cells (MSCs) by a sequential pathway of differentiation. MSCs develop either from ectoderm or mesoderm and commit into different undifferentiated precursors, which ...
Louis Casteilla, Patrick Laharrague
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In mammals, the adipose organ is composed of white adipocytes (primary site in energy storage) and of brown adipocytes (specialized in thermogenesis). Adipocytes arise from mesenchymal stem cells (MSCs) by a sequential pathway of differentiation. MSCs develop either from ectoderm or mesoderm and commit into different undifferentiated precursors, which ...
Louis Casteilla, Patrick Laharrague
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Remodeling on adipocytic physiology of organophosphorus esters in mature adipocytes
Environmental Pollution, 2022The emerging endocrine disruption chemicals organophosphate esters (OPEs) pose high risk of metabolic disruption. However, limited information is available on physiological disturbance of OPEs on adipose, a major endocrine and metabolic organ. In this study, physiological change was investigated after exposing 3T3-L1fully differentiated adipocytes to ...
Ying Liu +6 more
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2003
There are several preadipocyte cell lines reported, but in this chapter, we will describe mainly the 3T3-L1 cells, which are best characterized and widely used for molecular biological studies. The 3T3-L1 cells were clonally isolated by Green and Kehinde from 3T3-Swiss albino.
S, Gamou, Y, Shimizu, N, Shimizu
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There are several preadipocyte cell lines reported, but in this chapter, we will describe mainly the 3T3-L1 cells, which are best characterized and widely used for molecular biological studies. The 3T3-L1 cells were clonally isolated by Green and Kehinde from 3T3-Swiss albino.
S, Gamou, Y, Shimizu, N, Shimizu
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Adipocyte Mineralocorticoid Receptor
2019Mineralocorticoid receptor (MR) has been recently identified in adipose tissue, where its excessive activation contributes to several metabolic derangements often observed in obesity and metabolic syndrome. Recent findings support the existence of a bidirectional cross-talk between adipose tissue and adrenal glands, contributing to obesity-related ...
Infante M. +4 more
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Trends in Endocrinology & Metabolism, 2018
Adipocytes are lipid-rich parenchymal cells contained in a very plastic organ, whose composition can undergo striking physiologic changes. In standard conditions the organ contains white and brown adipocytes which play opposite roles: lipid storage to meet metabolic requirements and lipid burning for thermogenesis, respectively.
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Adipocytes are lipid-rich parenchymal cells contained in a very plastic organ, whose composition can undergo striking physiologic changes. In standard conditions the organ contains white and brown adipocytes which play opposite roles: lipid storage to meet metabolic requirements and lipid burning for thermogenesis, respectively.
openaire +2 more sources