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Adipocyte–Brain: Crosstalk

2010
The initial discovery of leptin, an appetite-suppressing hormone originating from fat tissue, substantially supported the idea that fat-borne factors act on the brain to regulate food intake and energy expenditure. Since then, a growing number of cytokines have been found to be released from adipose tissue, thus acting in an endocrine manner.
Hendrik Lehnert   +2 more
openaire   +3 more sources

Insulin signaling in the adipocyte

International Journal of Obesity, 2000
Mammalian adipose tissue serves a number of functions, including storage of nutrients for periods of fasting and control of organismal metabolism. Critical to these functions is the capacity of the fat cell to respond to insulin with a significant increase in glucose uptake.
Morris J. Birnbaum   +2 more
openaire   +3 more sources

The adipocyte as an endocrine cell1

Journal of Animal Science, 2004
Communication between adipose and other tissues has been hypothesized since at least the 1940s to be bidirectional. Despite this expectation, early progress was largely limited to adipose tissue's role in metabolism and storage of fatty acids, its development, and its response to endocrine and neural cues.
openaire   +3 more sources

Adipocytes and Cardiometabolic Risk

American Journal of Therapeutics, 2012
To describe the link between adipocytes and cardiometabolic risk and present mechanisms by which obesity contributes to dysglycemia, dyslipidemia, hypertension, and a prothrombotic, inflammatory state favoring atherogenesis. Review of relevant literature compiled via a literature search (PUBMED) of English-language literature publications between 1994 ...
openaire   +3 more sources

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

Nature Reviews Molecular Cell Biology, 2008
Adilson Guilherme   +2 more
exaly  

Forming functional fat: a growing understanding of adipocyte differentiation

Nature Reviews Molecular Cell Biology, 2011
Ana G Cristancho
exaly  

Adipocyte differentiation from the inside out

Nature Reviews Molecular Cell Biology, 2006
Evan D Rosen, Ormond A Macdougald
exaly  

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