Results 201 to 210 of about 94,652 (323)

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Effect of Combined Grape Seed (<i>Vitis vinifera</i>) and Garlic (<i>Allium sativum</i>) Extracts on Adipogenesis in the 3T3-L1 Preadipocyte Line. [PDF]

Int J Mol Sci
García-Dávila S, Cifuentes C, Gracia I, Gómez LA, Llorens S.   +4 more
europepmc   +1 more source

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

Toward “Obesityomics”: Domain‐Specific Omics in Precision Obesity Medicine with a Brief AI Perspective

Obesity Reviews, EarlyView.
ABSTRACT Background Obesity's global rise has outpaced the effectiveness of “one‐size‐fits‐all” prevention and treatment strategies. The promise of precision medicine lies in addressing the etiological and biological diversity of obesity and transforming it into actionable endotypes.
Nadia Abu Samra, Sara G. I. Suliman, Mohammed Al‐Hadad, Dorret I. Boomsma, Fadwa Alhantoobi, Maithah Alsamahi, Haneen Abufarajallah, Alia Al Tikriti, Zeyar Aung, Selena Richards, Abdulrahim Sajini, Mira Mousa, Fatima Sulaiman, Wael Osman   +13 more
wiley   +1 more source

Semi-automated, evidence-based workflow for selection of reference chemicals for the validation of NAMs: a case study with the adipogenesis assay. [PDF]

NAM J
Farnezi HCM, Lentz SBI, Legler J, Kamstra JH.   +3 more
europepmc   +1 more source

Investigating Overweight and Obesity Risk in Shift Workers Using Omics Technologies

Obesity Reviews, EarlyView.
ABSTRACT Night shift workers are at higher risk of developing overweight and obesity. The disruption of the physiological circadian rhythm leads to metabolic alterations, such as decreased insulin sensitivity, increased adipogenesis, and inflammation, with effects on their health and leading, among other diseases, to obesity.
Katrin Scionti, Ivana Václavková, Vanessa Schoissengeier, Karl‐Heinz Wagner   +3 more
wiley   +1 more source

<i>Larimichthys crocea</i>-Derived Calcium-Chelating Peptides Attenuate Leuprorelin-Induced Bone Loss and Lipid Metabolic Alterations in Mice. [PDF]

Mar Drugs
Wu X, Zheng S, Liu F, Liu J, Zhuang Y, Li D, Huang W.   +6 more
europepmc   +1 more source

AQP1 Corrects Acinar Cells’ Secretion Deficits in Sjögren's Disease

Oral Diseases, EarlyView.
ABSTRACT Introduction Sjögren's disease (SjD) is a systemic autoimmune disease characterized by dry mouth, dry eyes, and profound fatigue. Preclinical studies suggest that AQP1 gene expression in salivary glands corrects salivary hypofunction in preclinical and clinical studies of radiation‐induced xerostomia and improves salivary and lacrimal function
Paola Perez, Blake M. Warner, Youngmi Ji, Sandra Afione, Thomas J. F. Pranzatelli, Margaret E. Beach, Zohreh Khavandgar, Margie Grisius, Eileen Pelayo, Daniel Martin, NIDCD/NIDCR Genomics and Computational Biology Core, Alan N. Baer, John A. Chiorini   +12 more
wiley   +1 more source

Potential Role for the Ubiquitin Ligase SIAH2 in Modulating Bone Morphology and Adiposity. [PDF]

Calcif Tissue Int
Scott MC, Ghosh B, Kilroy G, Lecka-Czernik B, Floyd ZE.   +4 more
europepmc   +1 more source

Single‐Cell Transcriptomics Reveals the FA9–VAP Module Regulating Fatty Acid Accumulation in Soybean Seeds

Plant Biotechnology Journal, EarlyView.
ABSTRACT As a major commercial legume crop, soybean ranks among the world's most significant sources of edible oil and plant protein. We previously identified a SEIPIN homologue (FA9) at the fatty acid 9 locus that promotes fatty acid accumulation in soybean.
Hui Li, Tianshu Li, Xiaorui Xu, Jinhang Cui, Xin Chen, Jingyi Huang, Jia Song, Cui Mu, Xinyu Hong, Chunyan Liu, Ning Wang, Xue Han, Sui Wang, Qingshan Chen, Zhaoming Qi   +14 more
wiley   +1 more source