Results 201 to 210 of about 56,993 (237)
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Adipogenesis from Bovine Precursors
2018Cultured meat, or tissue engineered meat, is a promising alternative to conventional meat production. In order to realistically mimic the multiple tissue types found in beef, food-compatible methods for bovine fat tissue engineering must be developed.
Mehta, Frea +2 more
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Transcriptional control of adipogenesis
Current Opinion in Cell Biology, 1998Adipocyte differentiation is coordinatedly regulated by several transcription factors. C/EBP beta, C/EBP delta and ADD-1/SREBP-1 are active early during the differentiation process and induce the expression and/or activity of the peroxisome proliferator activated receptor-gamma (PPAR gamma), the pivotal coordinator of the adipocyte differentiation ...
L, Fajas, J C, Fruchart, J, Auwerx
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New developments in adipogenesis
Trends in Endocrinology & Metabolism, 2009The obesity epidemic has focused attention on adipose tissue and the development of fat cells (i.e. adipocytes), which is known as adipogenesis. Peroxisome proliferator-activated receptor gamma and CCAAT/enhancer-binding proteins have emerged as master regulators of adipogenesis, and recent genome-wide studies have indicated widespread overlap in their
Martina I, Lefterova, Mitchell A, Lazar
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Transcriptional Regulation of Adipogenesis
Comprehensive Physiology, 2017ABSTRACTAdipocytes are the defining cell type of adipose tissue. Once considered a passive participant in energy storage, adipose tissue is now recognized as a dynamic organ that contributes to several important physiological processes, such as lipid metabolism, systemic energy homeostasis, and whole‐body insulin sensitivity.
Paula, Mota de Sá +3 more
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Adipogenesis for soft tissue reconstruction
Current Opinion in Organ Transplantation, 2019Purpose of review It has been increasingly common to use adipose tissue for regenerative and reconstructive purposes. Applications of autologous fat transfer and different stem cell therapies have significant limitations and adipose tissue engineering may have the potential to be an important strategy in the reconstruction of ...
Huseyin, Karagoz +3 more
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Hormonal Regulation of Adipogenesis
Comprehensive Physiology, 2017ABSTRACTAdipose tissue includes multiple anatomical depots that serve as an energy reserve that can expand or contract to maintain metabolic homeostasis. During normal growth and in response to overnutrition, adipose tissue expands by increasing the volume of preexisting adipocytes (hypertrophy) and/or by generating new adipocytes (hyperplasia) via ...
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Nuclear Hormone Receptors and Adipogenesis
Critical Reviews in Eukaryotic Gene Expression, 1998Adipocytes provide a model cell system for exploring the complexities of nuclear hormone receptor transcriptional regulation. Adipocytes produce lipid and cholesterol metabolites which can serve as activating ligands for many of the classic and "orphan" nuclear hormone receptors.
J M, Gimble +3 more
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2017
In obesity, the process of adipogenesis largely determines the number of adipocytes in body fat depots. Adipogenesis is regulated by several adipocyte-selective microRNAs (miRNAs) and transcription factors that modulate adipocyte proliferation and differentiation. However, some miRNAs block expression of master regulators of adipogenesis. Additionally,
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In obesity, the process of adipogenesis largely determines the number of adipocytes in body fat depots. Adipogenesis is regulated by several adipocyte-selective microRNAs (miRNAs) and transcription factors that modulate adipocyte proliferation and differentiation. However, some miRNAs block expression of master regulators of adipogenesis. Additionally,
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Obesity, adipogenesis and insulin resistance
Endocrinología y Nutrición (English Edition), 2011Insulin resistance precedes the development of type 2 diabetes mellitus and is also a common denominator in the so-called metabolic syndrome. Although the cause of insulin resistance has not been fully elucidated, it seems clear that lifestyle changes, including little physical exercise and constant access to food, particularly in developed and ...
Manuel, Ros Pérez, Gema, Medina-Gómez
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Adipogenesis: cellular and molecular aspects
Best Practice & Research Clinical Endocrinology & Metabolism, 2005Obesity and lipoatrophy are major risks for insulin resistance, non-insulin-dependent diabetes and cardiovascular disease. In the past three decades, significant advances have been made in delineating the key transcription factors of adipogenesis, as well as extracellular effectors and intracellular signalling pathways that regulate fat cell formation.
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