Results 181 to 190 of about 69,441 (277)

Time‐Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity: The TREAD Randomized Control Trial

Obesity, Volume 34, Issue 7, Page 1395-1408, July 2026.
ABSTRACT Objective Examine time‐restricted eating (TRE) as a strategy to promote weight loss and cardiometabolic health in adults with obesity. Methods TRE in obesity and ADipose Tissue (TREAD) was a single‐center 12‐week RCT, involving 1:1 randomization to 10‐h TRE versus standard of care (SOC) in adults with obesity (BMI 30–50 kg/m2) without diabetes
Michael J. Wilkinson, Erika Padilla, Yuqi Wang, Sawye Raygani, Emily N. C. Manoogian, Kyla Laing, Khang Tong, Lin Liu, David Van, Justina Nguyen, Alan R. Saltiel, Shannon M. Reilly, Monica O'Neal, Satchidananda Panda, Amit R. Majithia, Pam R. Taub   +15 more
wiley   +1 more source

Metabolomic profiling reveals dynamic lipid reprogramming during adipogenesis in 3T3-L1 cells. [PDF]

Front Mol Biosci
Shi N, Huang Z, Liu J, Sun W, Li J.
europepmc   +1 more source

Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies

The Journal of Pathology, Volume 269, Issue 3, Page 363-380, July 2026.
Abstract Dystrophinopathies are caused by pathogenic variants in the DMD gene, resulting in partial (Becker) or complete loss (Duchenne) of dystrophin. Becker (BMD) and Duchenne muscular dystrophy (DMD) are characterized by progressive muscle wasting, fatty replacement, fibrosis, and loss of function.
Laura GM Heezen, Qirong Mao, Stefan Nicolau, Claudio Novella Rausell, Julia van der Weerd, Jan Kueckelhaus, Rasya Gokul Nath, Jordi Diaz‐Manera, Hermien E Kan, Erik H Niks, Maaike van Putten, Annemieke Aartsma‐Rus, Kevin M Flanigan, Ahmed Mahfouz, Pietro Spitali   +14 more
wiley   +1 more source

<i>Primula nutans</i> Georgi Extract Inhibits Early Adipogenesis Through CHOP-Associated Regulation and Ameliorates Obesity and Insulin Resistance. [PDF]

Int J Mol Sci
Roh N, Park K, Le D, Kim E, Dang T, Dinh T, Bazarragchaa B, Kim SY, Suh SS, Kim JJ, Lee M, Seo JB.   +11 more
europepmc   +1 more source

Clonal Analyses Reveal the Impact of Hematopoietic Stem and Progenitor Cell Aging on T Cell Development

Aging Cell, Volume 25, Issue 7, July 2026.
This study explored whether the decline in thymic output with age is due to intrinsic defects in aged hematopoietic stem and progenitor cells. With age, the proportion of lymphoid‐biased (Ly‐)HSCs decreased in the bone marrow and early thymic progenitor (ETP) cell number declined in the thymus.
Julia Gensheimer, Jessica LaGosh, Emma R. Moulton, Victoria Sun, Stephanie C. de Barros, Encarnacion Montecino‐Rodriguez, Gloria Yiu, Xuegang Yuan, Kenneth Dorshkind, Gay M. Crooks   +9 more
wiley   +1 more source

C/EBPδ as a Regulatory Node in Adipocytes: Roles in Differentiation, Metabolism, and Immune Function. [PDF]

Biomolecules
Ma S, Lai M, Li T, Wang L, Rong X.
europepmc   +1 more source

Bidirectional Relationship and Shared Mechanisms Between Sarcopenia and Osteoporosis: An Observational Study Integrating Genomic, Proteomic, and Metabolomic Data

Aging Cell, Volume 25, Issue 7, July 2026.
This study investigated the bidirectional relationship and shared mechanisms between sarcopenia and osteoporosis using data from the UK Biobank. Our findings indicated that the two conditions may act as reciprocal risk factors, with multiple potential biomarkers mediating the muscle‐bone relationship and suggested possible shared signals between the ...
Siqi Xu, Simin Wen, Xizeng Zong, Jianwei Zhu, Qiuling Du, Yu Li, Kunyan Wang, Peihua Cao, Changhai Ding, Yan Zhang, Guangfeng Ruan   +10 more
wiley   +1 more source

Extensive enhancer crosstalk controls PPARG2 activation during adipogenesis. [PDF]

Nat Commun
Cetnarowska A, Hyldahl M, Nygård M, Dashti H, Hansen BV, Holm LK, Madsen K, Madsen MS, Shukla V, Durmaz Mitchell E, Rauch A, Madsen JGS, Claussnitzer M, Mandrup S.   +13 more
europepmc   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source

Dynamic m⁶A methylation during bovine preadipocyte differentiation and functional implication of the m⁶A writer METTL14. [PDF]

BMC Genomics
Zhang D, Du J, Gao N, Qiu H, Li H, Mei C, Zan L.   +6 more
europepmc   +1 more source