Results 161 to 170 of about 69,441 (277)
Adipose Tissue Plasticity and Adipogenesis: From Cellular Mechanisms to Therapeutic Targets in Obesity. [PDF]
Rocha S +3 more
europepmc +1 more source
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos +7 more
wiley +1 more source
Adipogenesis Under Leptin Control: Mechanisms and Model-Specific Effects. [PDF]
Abu Na'aim A +5 more
europepmc +1 more source
ABSTRACT This study aimed to investigate how maternal feed restriction at different gestational stages alters the expression of novel long non‐coding RNAs (lncRNAs) in the skeletal muscle of goat offspring. LncRNAs are emerging as important regulators of biological processes, including myogenesis, yet their role in fetal programming remains largely ...
Maria M. M. Muniz +8 more
wiley +1 more source
Molecular mechanisms of anti-adipogenesis by tumour necrosis factor-alpha
In this thesis, a candidate approach was taken to analyse the temporal characteristics of gene expression during TNF-α induced anti-adipogenesis. This suggested that TNF-α might activate Wnt/β-catenin signalling during anti-adipogenesis.
Cawthorn, W P
core
<i>Zingiber officinale</i> Leaf Subcritical Water Extract Suppresses Adipogenesis and Lipogenesis in 3T3-L1 Adipocytes via the AMPK-SREBP-1c Signaling Pathway. [PDF]
Jun EM +4 more
europepmc +1 more source
The function of bromodomain‐containing proteins in regulating gene transcription is reviewed here, including the development of chemical probes and targeted protein degradation modalities (e.g., PROTACs). This extends to clinical efforts targeting the BET bromodomain‐containing proteins. Challenges of selectivity, future prospects, and the differential
Cole R. Scholtz, William C. K. Pomerantz
wiley +1 more source
The calreticulin saga: Focal adhesion to adipogenesis
Calreticulin is a multifunctional ER resident protein that participates in calcium homeostasis and modulation of gene expression, most notably those of genes involved in cell adhesion. Calreticulin has three domains: the N, P and the C domain.
Szabo, Eva
core
Dextromethorphan Modulates the Osteogenic-Adipogenic Balance in Rat Bone Marrow Mesenchymal Stem Cells. [PDF]
Lin JH, Luo YP, Ting PC, Ko MP, Yang KT.
europepmc +1 more source
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid +5 more
wiley +1 more source

