Results 161 to 170 of about 69,441 (277)

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Adipogenesis Under Leptin Control: Mechanisms and Model-Specific Effects. [PDF]

open access: yesInt J Mol Sci
Abu Na'aim A   +5 more
europepmc   +1 more source

Gestational Feed Restriction Induces Differential Expression of Novel Long Non‐Coding RNAs in Offspring Skeletal Muscle

open access: yesAnimal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT This study aimed to investigate how maternal feed restriction at different gestational stages alters the expression of novel long non‐coding RNAs (lncRNAs) in the skeletal muscle of goat offspring. LncRNAs are emerging as important regulators of biological processes, including myogenesis, yet their role in fetal programming remains largely ...
Maria M. M. Muniz   +8 more
wiley   +1 more source

Molecular mechanisms of anti-adipogenesis by tumour necrosis factor-alpha

open access: yes, 2008
In this thesis, a candidate approach was taken to analyse the temporal characteristics of gene expression during TNF-α induced anti-adipogenesis. This suggested that TNF-α might activate Wnt/β-catenin signalling during anti-adipogenesis.
Cawthorn, W P
core  

Eyes Toward the Clinic: Selective Inhibition and Degradation Approaches to Bromodomain‐Containing Proteins

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
The function of bromodomain‐containing proteins in regulating gene transcription is reviewed here, including the development of chemical probes and targeted protein degradation modalities (e.g., PROTACs). This extends to clinical efforts targeting the BET bromodomain‐containing proteins. Challenges of selectivity, future prospects, and the differential
Cole R. Scholtz, William C. K. Pomerantz
wiley   +1 more source

The calreticulin saga: Focal adhesion to adipogenesis

open access: yes, 2007
Calreticulin is a multifunctional ER resident protein that participates in calcium homeostasis and modulation of gene expression, most notably those of genes involved in cell adhesion. Calreticulin has three domains: the N, P and the C domain.
Szabo, Eva
core  

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid   +5 more
wiley   +1 more source

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