Results 151 to 160 of about 94,652 (323)

Pref-1, a Gatekeeper of Adipogenesis [PDF]

, 2013
Preadipocyte factor 1 (Pref-1, also called Dlk1/ FA1) is a molecular gatekeeper of adipogenesis by maintaining preadipocyte state and preventing adipocyte differentiation.
Hei Sook eSul, Carolyn S. Hudak, Hei Sook Sul, Carolyn S Hudak   +3 more
core   +1 more source

Caspase-1 Deficiency Modulates Adipogenesis through Atg7-Mediated Autophagy: An Inflammatory-Independent Mechanism

Biomolecules
Obesity stands as a significant risk factor for type 2 diabetes, hyperlipidemia, and cardiovascular diseases, intertwining increased inflammation and decreased adipogenesis with metabolic disorders.
Yumeng Wang, Gaojun Chen, Min Xu, Yewei Cui, Weijiong He, Hongxiang Zeng, Ting Zeng, Rui Cheng, Xi Li   +8 more
doaj   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

MiR-4769-3p suppresses adipogenesis in systemic sclerosis by negatively regulating the USP18/VDAC2 pathway

iScience
Summary: Systemic sclerosis (SSc) is an autoimmune disease affecting multiple tissues. The underlying causes and mechanisms of subcutaneous adipose tissue (SAT) loss in SSc remain unclear.
Bingsi Tang, Jiangfan Yu, Rui Tang, Xinglan He, Jiani Liu, Licong Liu, Zehong Song, Yaqian Shi, Zhuotong Zeng, Yi Zhan, Xiangning Qiu, Yangfan Xiao, Yan Ding, Rong Xiao   +13 more
doaj   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori, Pedro Garcia Caparros, Antonella Castagna, Luisa Custódio, Valentina Lazazzara, Claus Krogh Madsen, Felicia Menicucci, Maria João Rodrigues, Katalin Solymosi, Jose Ramon Acosta Motos   +9 more
wiley   +1 more source

Adipogenesis 에서 Nupr1 의 역할

, 2022
선진국의 비만율 증가는 제 2 형 당뇨병, 심혈관 질환 등과 같은 대사 질환의 발생 증가와 상관관계가 있기 때문에 심각한 문제로 대두되고 있다. 지방세포분화 조절 메커니즘은 비만과 같은 신진대사 질환과의 상관관계 때문에 널리 연구되는 주제이다. 그러므로, 지방세포분화를 조절하는 생물학적 네트워크를 연구하는 것은 비만의 병리생리학에 대한 더 큰 이해를 가져올 수 있다. 지방세포 분화는 초기 지방 분화와 후기 지방 분화과정을 거친다.
MENDES DUARTE TATIANA PATRICIA
core  

Combined effects of kombucha consumption and aerobic exercise on oxidative stress and metabolic parameters in Wistar rats

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background Kombucha, a fermented tea containing symbiotic bacteria and yeast, and aerobic exercise each confer distinct health benefits, but their combined effects remain poorly understood. This study investigated the combined effects of consuming kombucha fermented for 7 days and performing moderate aerobic exercise on physiological outcomes ...
Jean Carlos Costa Nogueira, Luis Paulo Santos Ribas, Raquel Moura, Jean Ramos Boldori, Alexsander Pedroso Garcia, Kaueli Rodrigues Amaral, Franciele Aline Smaniotto, Tatiana Emanuelle, Cristiane Casagrande Denardin   +8 more
wiley   +1 more source

High Fructose Intake and Adipogenesis

, 2019
In modern societies, high fructose intake from sugar-sweetened beverages has contributed to obesity development. In the diet, sucrose and high fructose corn syrup are the main sources of fructose and can be metabolized in the intestine and transported ...
Fausto Sánchez-Muñoz, L. Gabriela Sánchez-Lozada, Rodrigo Romero-Nava, Roxana Carbó, Adrián Hernández-Díazcouder   +4 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

New potential fat marker genes, selected based on the coupling model of adipogenesis and reverse adipogenesis.

, 2013
Gene expression analysis was performed using qRT-PCR and the expression values were normalized to GAPDH for stepwise assessment of adipogenesis and reverse adipogenesis (dedifferentiation). Gene expression of new potential fat marker genes (A) APCDD1, (B)
Jochen Ringe (46862), Thomas Häupl (18992), Stefan Stich (438448), Jan Eucker (427775), Mujib Ullah (438447), Michael Sittinger (883)   +5 more
core   +1 more source