Results 271 to 280 of about 94,652 (323)

Dosing PPARγ Activation With Light Using Fast Relaxing Photoswitches

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 40, 28 September 2026.
To achieve spatiotemporal control over PPARγ activity, we designed the fast‐relaxing photoswitchable agonist 6 that selectively activates PPARγ in its light‐induced Z‐state and relaxes within seconds (t1/2 47 s) to the inactive E‐state. This unique profile allowed light‐dosed receptor activation in in vitro settings, enabling biological studies on ...
Loris Knümann   +7 more
wiley   +1 more source

SOCS3 Stabilizes PARP1 to Suppress Adipogenic Transcription and Abdominal Adipogenesis in Avian. [PDF]

open access: yesFASEB J
Wang Z   +9 more
europepmc   +1 more source

Metabolic Shifts Precede Cognitive Decline in the Male hAß‐KI Alzheimer's Mouse Model

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
A major barrier in Alzheimer's disease (AD) research is the lack of animals that recapitulate sporadic AD. The humanized amyloid‐beta knock‐in mice (hAß‐KI) exhibit age‐dependent cognitive decline and beta‐amyloid accumulation. However, limited research has been conducted related to AD risk factors and sex‐specific responses.
Evelin Melekh   +8 more
wiley   +1 more source

Targeting AHNAK ameliorates osteonecrosis of the femoral head and affects adipogenic pathways involving Smad/PPARγ. [PDF]

open access: yesBone Joint Res
Chen MF   +7 more
europepmc   +1 more source

Citrate reduced gold nanoparticles lowered lipid content in differentiated 3T3-L1 adipocytes by altering the expression of adipogenic genes. [PDF]

open access: yesDiscov Nano
Hyera A   +7 more
europepmc   +1 more source

Adipose precursor cell-derived clusterin promotes homeostasis in subcutaneous adipose tissue. [PDF]

open access: yesStem Cell Reports
Chen Z   +9 more
europepmc   +1 more source

Optimized Metabolic Conditions Reveal the Adipogenic Competence of Wharton's Jelly MSCs: Insight from Literature Review and Experimental Validation. [PDF]

open access: yesStem Cell Rev Rep
Pinault C   +11 more
europepmc   +1 more source

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