Results 261 to 270 of about 94,652 (323)

The Ageing Adipose Paradox: Implications for Metabolic Health. [PDF]

Diabetes Obes Metab
Matar DB, Elahi MA, Nassar WK, Alotaibi MI, Murphy D, Fakhoury HMA, Aljada A.   +6 more
europepmc   +1 more source

From Regenerative to Degenerative Niche: Multicellular Crosstalk and Population Dynamics in Skeletal Muscle Aging

Aging Cell, Volume 25, Issue 10, October 2026.
Aging transforms the skeletal muscle microenvironment from a balanced, regenerative niche into a maladaptive, degenerative state. This review highlights how disrupted multicellular crosstalk drives chronic inflammation, fibrosis, and neuromuscular dysfunction, ultimately compromising tissue repair and fueling sarcopenia.
Seongwan Kim, Min Ju Kim, Yong Ryoul Yang   +2 more
wiley   +1 more source

Lipoedema and Obesity Misclassification: A Phenotype Based Approach to Cardiometabolic Risk Beyond Body Mass Index

Clinical Obesity, Volume 16, Issue 5, October 2026.
Clinical recognition of the lipoedema phenotype and principal differential diagnoses. ABSTRACT Lipoedema is a painful adipose tissue disorder marked by disproportionate limb fat and often misclassified as generalized obesity or lymphoedema. This review examines its metabolic phenotype and implications for cardiometabolic assessment and management ...
Ron T. Varghese, Diana G. Varghese
wiley   +1 more source

<i>Zingiber officinale</i> Leaf Subcritical Water Extract Suppresses Adipogenesis and Lipogenesis in 3T3-L1 Adipocytes via the AMPK-SREBP-1c Signaling Pathway. [PDF]

Int J Med Sci
Jun EM, Kim JY, Choe JS, Park EJ, Lee HJ.   +4 more
europepmc   +1 more source

Identification of miRNA-mRNA Regulatory Networks Reveals Potential Key miRNAs in Goat Intramuscular and Subcutaneous Adipose Formation. [PDF]

Animals (Basel)
Xing J, Ma H, Wang J, Lin Y, Wang Y, Xue F, Li X, Dong Y, Li Y, Wang Y, Shi H, Liu W.   +11 more
europepmc   +1 more source

Refining the Genetic Contribution to Type 2 Diabetes Subtypes

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9450-9460, October 2026.
ABSTRACT Background Type 2 diabetes (T2D) is a complex and highly heterogeneous disease driven in part by genetic predisposition and can be stratified into clinical subgroups to aid disease management. We recently grouped T2D subjects in the Qatar Biobank (QBB) cohort into Severe Insulin‐Deficient Diabetes (SIDD), Severe Insulin‐Resistant Diabetes ...
Nayra M. Al‐Thani, Salman M. Toor, Umm‐Kulthum Ismail Umlai, Usama Aliyu, Karsten Suhre, Omar M. E. Albagha   +5 more
wiley   +1 more source

Developmental Cellular Programming: stage-specific architecting muscle and adipose tissues for high-quality meat production. [PDF]

J Anim Sci Biotechnol
Wang B.
europepmc   +1 more source

The mediating role of genes in the influence of intestinal flora on type 2 diabetes and the screening of diagnostic markers

Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1816-1834, October 2026.
Using Mendelian randomization, TWAS/eQTL analysis, machine learning, and single‐cell RNA sequencing, this study identified gut microbiota taxa causally linked to type 2 diabetes, candidate mediator genes, and diagnostic markers (BEND7, BLVRA, C1orf85, and LAMC1).
Yu‐yang Chen, Yi‐fan Shi, Xin‐yue Zhang, Jing‐yue Zhang, Shi‐mao Zhang, Heng‐xia Zhao, De‐liang Liu   +6 more
wiley   +1 more source

Targeting Aromatase and 5-α-Reductase to Limit Dysfunctional Adipogenesis in Multiple Symmetric Lipomatosis. [PDF]

Biomedicines
Milan G, Compagnin C, Zucal I, Perale G, Bettini S, Pilatone A, De Monti M, Harder Y, Parodi C, Schmauss D, Vindigni V, Bassetto F, Felthaus O, Oliinyk D, Prantl L, Busetto L.   +15 more
europepmc   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, Volume 27, Issue 10, October 2026.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source