Results 241 to 250 of about 94,652 (323)

Rev‐erb‐α in Skeletal Muscle Adaptation: Integrating Circadian Control Mechanisms and Exercise Dynamic Responses

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Circadian rhythms orchestrate a host of biological processes in a time‐dependent manner to maintain homeostasis in response to exercise. Within this framework, Rev‐erb‐α, an intracellular nuclear receptor and transcriptional regulator, transcends its role in circadian rhythms to drive myogenesis, muscle remodeling, primary metabolism, and ...
Ivo Vieira de Sousa Neto, Alisson Luiz da Rocha, Ana Paula Pinto, Eliézer Lucas Pires Ramos, Eduardo Rochete Ropelle, José Rodrigo Pauli, Ellen Cristini de Freitas, Adelino Sanchez Ramos da Silva   +7 more
wiley   +1 more source

The extracellular matrix protein SNED1 affects self-renewal, proliferation and adipogenic differentiation of human adipose stem/progenitor cells. [PDF]

Adipocyte
Großmann S, Waldegger P, Deutinger T, Zwerschke W.   +3 more
europepmc   +1 more source

Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Urolithin A (UA) and urolithin B (UB) are gut microbiota‐derived metabolites of ellagitannins reported to influence mitochondrial function, inflammation and muscle metabolism. Their comparative transcriptomic effects in human skeletal muscle cells remain undefined.
Yves Henrotin, Antoine Florin, Christelle Sanchez, Prescilia Centonze, Tiago Pinto Coelho, Sophie Bekisz, Jean‐Emile Dubuc, Olivier Galand, Cécile Lambert   +8 more
wiley   +1 more source

Curcumin Opposes Perfluorodecanoic Acid-Induced Adipogenesis Through the PPARγ/C/EBPα Axis in 3T3-L1 Cells. [PDF]

Toxics
Darcan A, Çil EN, Soysal Y.
europepmc   +1 more source

Chemotherapy‐Induced Skeletal Muscle Dysfunction and Cognitive Impairment: A Muscle‐Brain Mechanistic Framework With Implications for Exercise Oncology

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Chemotherapy commonly induces skeletal muscle dysfunction and cognitive impairment, complications that reduce treatment tolerance and quality of life. Skeletal muscle mass frequently declines during chemotherapy, with cohort studies reporting losses of 3%–10% across treatment courses, while chemotherapy‐induced cognitive impairment affects up ...
SoYoung Ahn, Jin‐Soo Kim, Daniel A. Galvao, Dennis R. Taaffe, Dong Hyun Yoon, Carolyn McIntyre, Christelle Schofield, Yoon Jung Chang, Jihee Min, Wook Song, Robert U. Newton   +10 more
wiley   +1 more source

Stress-coping phenotypes shape adipose tissue function and plasticity and modulate metabolic resilience. [PDF]

Transl Psychiatry
Mehta SK, Ben-Shachar M, Govindaraj S, Sen S, Segev A, Rahimi O, Gahramanov V, Luboshits G, Firer MA, Wollman A, Pinhasov A, Rosenzweig T.   +11 more
europepmc   +1 more source

Sustainable Overproduction of the Bacterial Pigment Indigoidine as a Natural Colorant: Stability Evaluation, Inhibition of Obesity‐Diabetes‐Related Digestive Enzymes, and Activation of AMPK–AKT

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Production of indigoidine (IND) increased from 1.04 to 2.76 g/L using an optimized LB medium composed of glucose, l‐glutamine, tryptone, yeast extract, MgSO4·7H2O, and KH2PO4. The IND has significant inhibition properties against amylase and lipase enzymes, stimulates AMPK and AKT pathways, and improves glucose uptake.
Tahani Ali Asseri
wiley   +1 more source

Ciliary Ift20 and Wwtr1 Coordinate Transforming Growth Factor‐β Receptor II Signaling to Maintain Bone–Fat Balance in Skeletal Homeostasis

MedComm, Volume 7, Issue 10, October 2026.
Deletion of Ift20 and Wwtr1 in osteoprecursors promoted adipogenic differentiation while suppressing osteogenesis and bone remodeling through dysregulation of TGF‐β signaling. Mechanistically, Ift20 stabilized TβRII by inhibiting c‐Cbl‐mediated ubiquitination and proteasomal degradation. In parallel, Wwtr1 functioned as a transcriptional regulator that
Yang Li, Yang Yang, Shuting Yang, Huijuan Chang, Yi‐Ping Li, Shuying Yang   +5 more
wiley   +1 more source

GLP-1 regulates osteo-adipogenic fate of BMSCs via HIF-2-AKT signaling and supports trabecular bone in glucocorticoid-induced osteoporosis. [PDF]

Stem Cell Reports
Yang Z, Li X, Wu N, Wang L, Lu Z, Wang L, Han S, Lu H.   +7 more
europepmc   +1 more source