Results 241 to 250 of about 69,441 (277)

Transcriptional control of adipogenesis

Current Opinion in Cell Biology, 1998
Adipocyte differentiation is coordinatedly regulated by several transcription factors. C/EBP beta, C/EBP delta and ADD-1/SREBP-1 are active early during the differentiation process and induce the expression and/or activity of the peroxisome proliferator activated receptor-gamma (PPAR gamma), the pivotal coordinator of the adipocyte differentiation ...
L, Fajas, J C, Fruchart, J, Auwerx
openaire   +2 more sources

Epigenetic regulation of adipogenesis

Current Opinion in Clinical Nutrition and Metabolic Care, 2012
Epigenetic regulation plays an essential role in cell differentiation, by allowing the establishment and maintenance of the gene-expression pattern of the mature cell type. Because of its importance in chronic diseases, adipogenesis is one of the best-studied differentiation processes.
Melina M, Musri, Marcelina, Párrizas
openaire   +2 more sources

Hormonal Regulation of Adipogenesis

Comprehensive Physiology, 2017
ABSTRACT Adipose tissue includes multiple anatomical depots that serve as an energy reserve that can expand or contract to maintain metabolic homeostasis. During normal growth and in response to overnutrition, adipose tissue expands by increasing the volume of preexisting adipocytes (hypertrophy) and/or by ...
openaire   +2 more sources

Gaining a solid grip on adipogenesis

Tissue and Cell, 2005
Obesity is presently being combated by fitness regimens, drugs and diet. Increasing our understanding of the physiology of adipocytes, by deducing the regulatory pathways involved in lipid metabolism and all aspects of adipogenesis, will provide alternative strategies to reduce adverse problems of obesity.
Fernyhough, M. E., Bucci, L. R., Hausman, G. J., Antonio, Jose, Vierck, J. L., Dodson, M. V.   +5 more
openaire   +3 more sources

Nuclear Hormone Receptors and Adipogenesis

Critical Reviews™ in Eukaryotic Gene Expression, 1998
Adipocytes provide a model cell system for exploring the complexities of nuclear hormone receptor transcriptional regulation. Adipocytes produce lipid and cholesterol metabolites which can serve as activating ligands for many of the classic and "orphan" nuclear hormone receptors.
J M, Gimble, C E, Robinson, S L, Clarke, M R, Hill   +3 more
openaire   +2 more sources

Adipogenesis from Bovine Precursors

2018
Cultured meat, or tissue engineered meat, is a promising alternative to conventional meat production. In order to realistically mimic the multiple tissue types found in beef, food-compatible methods for bovine fat tissue engineering must be developed.
Mehta, Frea, Theunissen, Ruud, Post, Mark J.   +2 more
openaire   +3 more sources

Adipogenesis for soft tissue reconstruction

Current Opinion in Organ Transplantation, 2019
Purpose of review It has been increasingly common to use adipose tissue for regenerative and reconstructive purposes. Applications of autologous fat transfer and different stem cell therapies have significant limitations and adipose tissue engineering may have the potential to be an important strategy in the reconstruction of ...
Huseyin, Karagoz, Fatih, Zor, Esra, Goktas, Vijay S, Gorantla   +3 more
openaire   +2 more sources

Hormonal Control of Adipogenesis^a

Annals of the New York Academy of Sciences, 1986
The concept that hormonal substances can alter the expression of entire developmental programs is in itself not particularly new. The ability to define conditions under which a specific hormone can precociously activate the differentiation of a well-defined population of cells and under which another hormone can both block and reverse such a ...
G M, Ringold, A B, Chapman, D M, Knight, F M, Torti   +3 more
openaire   +2 more sources

Oxygen-Dependent Regulation of Adipogenesis

2004
Publisher Summary This chapter discusses oxygen-dependent regulation of adipogenesis. Because O 2 sensingplays an important role in energy homeostasis and cell differentiation, O 2 tension can also control adipose tissue function by regulating adipogenesis. Hypoxia inhibits the oxidation of fatty acids in mitochondria, resulting in a relative state
Lillian M, Swiersz, Amato J, Giaccia, Zhong, Yun   +2 more
openaire   +2 more sources

Adipogenesis: cellular and molecular aspects

Best Practice & Research Clinical Endocrinology & Metabolism, 2005
Obesity and lipoatrophy are major risks for insulin resistance, non-insulin-dependent diabetes and cardiovascular disease. In the past three decades, significant advances have been made in delineating the key transcription factors of adipogenesis, as well as extracellular effectors and intracellular signalling pathways that regulate fat cell formation.
openaire   +2 more sources