Results 11 to 20 of about 39,668 (310)
RBP4: a controversial adipokine [PDF]
European Journal of Endocrinology, 2011 Adipose tissue is an endocrine organ secreting biologically active factors called adipokines that act on both local and distant tissues. Adipokines have an important role in the development of obesity-related comorbidities not only in adults but also in children and adolescents.
Primoz, Kotnik +2 more
openaire +3 more sources
Annales d'Endocrinologie, 2016 Adipose tissue is now widely recognized as "an organ" able to synthesize and secrete hundred factors collectively called adipokines. These secreted molecules exert pleiotropic actions, notably on the regulation of glucose and lipid metabolism, inflammation, reproduction, or angiogenesis.
Fève, Bruno +4 more
openaire +3 more sources
The Adipokines in Cancer Cachexia [PDF]
International Journal of Molecular Sciences, 2020 Cachexia is a devastating pathology induced by several kinds of diseases, including cancer. The hallmark of cancer cachexia is an extended weight loss mainly due to skeletal muscle wasting and fat storage depletion from adipose tissue. The latter exerts key functions for the health of the whole organism, also through the secretion of several adipokines.
Mannelli M. +3 more
openaire +2 more sources
Clinical and Experimental Pharmacology and Physiology, 2011 Summary1. Obesity is a major risk factor for cardiovascular disease. An increased body mass index (BMI) is associated with venous thromboembolism, myocardial infarction, stroke and stent thrombosis after percutaneous interventions. Studies in mouse models of obesity and induced arterial or venous thrombosis have provided insights into the mechanisms ...
Schaefer, Katrin +1 more
openaire +3 more sources
Ex vivo and in vivo regulation of lipocalin-2, a novel adipokine, by insulin [PDF]
, 2009 OBJECTIVE - Lipocalin-2, a novel adipokine, has been shown to be elevated in obese, insulin-resistant, and diabetic Subjects. We therefore sought to study the ex vivo and in vivo effects of insulin on lipocalin-2 levels in humans. RESEARCH DESIGN AND
Randeva, Harpal S. +6 more
core +1 more source
Adipokine als metabolische Prädiktoren [PDF]
, 2019 Adipokine sind Proteine, die aus dem Fettgewebe freigesetzt werden. Viele dieser Fettzell-sezernierten Proteine sind bei Adipositas dysreguliert und beeinflussen das Risiko für kardiometabolische Folgeerkrankungen. Die vorliegende Arbeit untersucht daher
Ebert, Thomas
core +2 more sources
Low serum cartonectin/CTRP3 concentrations in newly diagnosed Type 2 Diabetes Mellitus : in vivo regulation of Cartonectin by glucose [PDF]
, 2014 Objectives: Cartonectin is a novel adipokine of the C1q complement/TNF-related protein (CTRP) superfamily, with glucose lowering effects, anti-inflammatory and cardio-protective properties. We sought to investigate circulating cartonectin concentrations
Jing Chen +22 more
core +1 more source
, 2022 INTRODUCTION: Adipokines may play a role in the early stages of rheumatoid arthritis. This study evaluated the performance of adipokines in a Colombian population with early rheumatoid arthritis and its relationship with disease activity.
Bello-Gualtero, Juan Manuel +11 more
core +1 more source
Diagnostics, 2022 Renal cell carcinoma (RCC) is the most lethal genitourinary malignancy. Obesity is a risk factor for RCC development. The role of adipokines in the relationship between obesity and RCC requires confirmatory evidence in the form of a systematic review and
Sugania Malar Chinapayan +5 more
doaj +1 more source
Journal of Atherosclerosis and Thrombosis, 2011 Dysregulation of adipose tissue-derived bioactive molecules, termed adipokines, is recognized as common ground for insulin resistance and metabolic syndrome associated with obesity. However, adipokine dysregulation is paradoxically associated with lipodystrophy and lipoatrophy with aging.
Arai, Yasumichi +3 more
openaire +2 more sources