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RBP4: a controversial adipokine [PDF]
Adipose tissue is an endocrine organ secreting biologically active factors called adipokines that act on both local and distant tissues. Adipokines have an important role in the development of obesity-related comorbidities not only in adults but also in children and adolescents.
Primoz, Kotnik +2 more
openaire +4 more sources
Evaluation of the adipokine profile (adiponectin, resistin, adipsin, vaspin, and leptin) in patients with early rheumatoid arthritis and its correlation with disease activity [PDF]
INTRODUCTION: Adipokines may play a role in the early stages of rheumatoid arthritis. This study evaluated the performance of adipokines in a Colombian population with early rheumatoid arthritis and its relationship with disease activity.
Bello-Gualtero, Juan Manuel +11 more
core +1 more source
Adipose tissue is now widely recognized as "an organ" able to synthesize and secrete hundred factors collectively called adipokines. These secreted molecules exert pleiotropic actions, notably on the regulation of glucose and lipid metabolism, inflammation, reproduction, or angiogenesis.
Fève, Bruno +4 more
openaire +3 more sources
The Adipokines in Cancer Cachexia [PDF]
Cachexia is a devastating pathology induced by several kinds of diseases, including cancer. The hallmark of cancer cachexia is an extended weight loss mainly due to skeletal muscle wasting and fat storage depletion from adipose tissue. The latter exerts key functions for the health of the whole organism, also through the secretion of several adipokines.
Mannelli M. +3 more
openaire +2 more sources
Summary1. Obesity is a major risk factor for cardiovascular disease. An increased body mass index (BMI) is associated with venous thromboembolism, myocardial infarction, stroke and stent thrombosis after percutaneous interventions. Studies in mouse models of obesity and induced arterial or venous thrombosis have provided insights into the mechanisms ...
Schaefer, Katrin +1 more
openaire +3 more sources
Ex vivo and in vivo regulation of lipocalin-2, a novel adipokine, by insulin [PDF]
OBJECTIVE - Lipocalin-2, a novel adipokine, has been shown to be elevated in obese, insulin-resistant, and diabetic Subjects. We therefore sought to study the ex vivo and in vivo effects of insulin on lipocalin-2 levels in humans. RESEARCH DESIGN AND
Randeva, Harpal S. +6 more
core +1 more source
Low serum cartonectin/CTRP3 concentrations in newly diagnosed Type 2 Diabetes Mellitus : in vivo regulation of Cartonectin by glucose [PDF]
Objectives: Cartonectin is a novel adipokine of the C1q complement/TNF-related protein (CTRP) superfamily, with glucose lowering effects, anti-inflammatory and cardio-protective properties. We sought to investigate circulating cartonectin concentrations
Jing Chen +22 more
core +1 more source
A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion [PDF]
Adipocytes sense systemic nutrient status and systemically communicate this information by releasing adipokines. The mechanisms which couple nutritional state to adipokine release are unknown. Here, we investigated how Unpaired 2 (Upd2), a structural and
Housden, Benjamin E. +4 more
core +1 more source
Dysregulation of adipose tissue-derived bioactive molecules, termed adipokines, is recognized as common ground for insulin resistance and metabolic syndrome associated with obesity. However, adipokine dysregulation is paradoxically associated with lipodystrophy and lipoatrophy with aging.
Arai, Yasumichi +3 more
openaire +2 more sources
A review on the role of novel adipokine Isthmin-1 and Subfatin in human type 2 diabetes mellitus
Adipokines are essential for maintaining cardiovascular and metabolic balance. The term "adipokines" refers to peptides in the pancreas, brain, vascular system, liver, immune system and muscle.
Baydaa ahmed abed +3 more
doaj +1 more source

