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Adiponectin and Adiponectin Receptors [PDF]
Endocrine Reviews, 2005 Metabolic syndrome is thought to result from obesity and obesity-linked insulin resistance. Obesity in adulthood is characterized by adipocyte hypertrophy. Adipose tissue participates in the regulation of energy homeostasis as an important endocrine organ that secretes a number of biologically active "adipokines."Heterozygous peroxisome proliferator ...
Motohiro Sasaki +2 more
exaly +3 more sources
Adiponectin and Adiponectin Receptors in Atherosclerosis
Endocrine ReviewsAbstract Adiponectin is an abundantly secreted hormone that communicates information between the adipose tissue, and the immune and cardiovascular systems. In metabolically healthy individuals, adiponectin is usually found at high levels and helps improve insulin responsiveness of peripheral tissues, glucose tolerance, and fatty acid ...
, , Daskalopoulou Stella S
exaly +3 more sources
Influence of androgens on circulating adiponectin in male and female rodents. [PDF]
PLoS ONE, 2012 Several endocrine factors, including sex-steroid hormones are known to influence adiponectin secretion. Our purpose was to evaluate the influence of testosterone and of the synthetic non-aromatizable/non-5α reducible androgen 17β-hydroxyestra-4,9,11 ...
Joshua F Yarrow +5 more
doaj +1 more source
Adiponectin preserves metabolic fitness during aging
eLife, 2021 Adiponectin is essential for the regulation of tissue substrate utilization and systemic insulin sensitivity. Clinical studies have suggested a positive association of circulating adiponectin with healthspan and lifespan.
Na Li +19 more
doaj +1 more source
Stroke, 2005 Despite efforts at controlling traditional risk factors, stroke remains a devastating and all-too-common disease. Identifying new markers for patients at higher risk of stroke would aid in future risk factor management as well as potentially offering new venues for preventive therapies.
Miwa, Ryo, Tohru, Funahashi
openaire +4 more sources
Evidence for the Neuronal Expression and Secretion of Adiponectin
Cells, 2022 Peripheral adiponectin acts on the hypothalamus to inhibit energy expenditure and increase food intake through its receptors AdipoR1 and adipoR2. The hypothalamic expression of adiponectin is poorly documented.
Azénor Abgrall +8 more
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Relationship between adiponectin multimer levels and subtypes of cerebral infarction.
PLoS ONE, 2022 AimSerum adiponectin levels are decreased in patients with cerebral infarction. Adiponectin in circulation exists in three isoforms: high molecular weight (HMW), medium molecular weight (MMW), and low molecular weight (LMW) adiponectin. We measured serum
Noriko Tagawa +4 more
doaj +1 more source
International Journal of Noncommunicable Diseases, 2022 The biological functioning of adiponectin (APN) has been well understood for two decades. Numerous clinical and animal studies have paved an understanding of the exposed physiological functions of APN in obesity and its related disorders. APN mediates its action through its receptors to achieve its function.
Geetha Bhaktha +2 more
openaire +2 more sources
Adiponectin in Myopathies [PDF]
International Journal of Molecular Sciences, 2019 In skeletal muscle, adiponectin has varied and pleiotropic functions, ranging from metabolic, anti-inflammatory, insulin-sensitizing to regenerative roles. Despite the important functions exerted by adiponectin, the study of the hormone in myopathies is still marginal.
Tania Gamberi +2 more
openaire +2 more sources
Adiponectin: friend or foe in obesity and inflammation
Medical Review, 2022 Adiponectin is an adipokine predominantly produced by fat cells, circulates and exerts insulin-sensitizing, cardioprotective and anti-inflammatory effects.
Luo Liping, Liu Meilian
doaj +1 more source