Results 21 to 30 of about 92,933 (286)

Circulating High-Molecular-Weight (HMW) Adiponectin Level Is Related with Breast Cancer Risk Better than Total Adiponectin: A Case-Control Study. [PDF]

PLoS ONE, 2015
The level of total adiponectin, a mixture of different adiponectin forms, has been reported associated with breast cancer risk with inconsistent results. Whether the different forms play different roles in breast cancer risk prediction is unclear.
Ming-ming Guo, Xue-ning Duan, Shu-de Cui, Fu-guo Tian, Xu-chen Cao, Cui-zhi Geng, Zhi-min Fan, Xiang Wang, Shu Wang, Hong-chuan Jiang, Jian-guo Zhang, Feng Jin, Jin-hai Tang, Hong Liang, Zhen-lin Yang, Hai-bo Wang, Qi-tang Wang, Guo-lou Li, Liang Li, Shi-guang Zhu, Wen-shu Zuo, Li-yuan Liu, Lu Wang, Dan-dan Ma, Shu-chen Liu, Yu-juan Xiang, Lu Liu, Chun-miao Ye, Wen-zhong Zhou, Fei Wang, Li-xiang Yu, Zhong-bing Ma, Zhi-gang Yu   +32 more
doaj   +1 more source

Effects of telmisartan and ramipril on adiponectin and blood pressure in patients with type 2 diabetes [PDF]

, 2008
<b>Background:</b> Adiponectin is secreted by adipose tissue and may play a role in cardiovascular disease. We examined adiponectin levels in patients with type 2 diabetes who participated in the Telmisartan vs.
Fauvel, J.P., Raff, U., R. E. Schmieder, C. Delles, Ruilope, L.M., Mimran, A., J. P. Fauvel, Delles, C., U. Raff, A. Mimran, Schmieder, R.E., L. M. Ruilope   +11 more
core   +1 more source

Accuracy of circulating adiponectin for predicting gestational diabetes : a systematic review and meta-analysis [PDF]

, 2016
Aims/hypothesis Universal screening for gestational diabetes mellitus (GDM) has not been implemented, and this has had substantial clinical implications. Biomarker-directed targeted screening might be feasible.
Kelsey, Tom, Stamatina Iliodromiti, Nelson, Scott M., Iliodromiti, S, Sattar, N, Thomas W. Kelsey, Sattar, Naveed, Kelsey, TW, Robert S. Lindsay, Sassarini, J, Scott M. Nelson, Jennifer Sassarini, Sassarini, Jennifer, Naveed Sattar, Lindsay, Robert S., Nelson, SM, Iliodromiti, Stamatina, Kelsey, Thomas W., Lindsay, R, Nelson, S, Lindsay, RS   +20 more
core   +1 more source

Adiponectin and Adiponectin Receptors in Human Pheochromocytoma

Journal of Atherosclerosis and Thrombosis, 2009
Recent studies have demonstrated that serum adiponectin and its receptors in adipose and muscle tissues are suppressed in diabetic or obese individuals. Patients with pheochromocytoma are frequently diabetic.Using real-time PCR, we examined mRNA expressions of adiponectin (Adp) and adiponectin receptor 1 (AdpR1) and AdpR2 in pheochromocytoma tissues ...
Isobe, Kazumasa, FU, Ling, Tatsuno, Ichirou, Takahashi, Hideto, Nissato, Sumiko, Hara, Hisato, Yashiro, Toru, Suzukawa, Kazumi, Takekoshi, Kazuhiro, Shimano, Hitoshi, Kawakami, Yasushi   +10 more
openaire   +3 more sources

Adiponectin, Adiponectin Receptors, and Epigenetic Regulation of Adipogenesis [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2011
We studied the molecular mechanism of obesity-induced insulin resistance and adipogenesis. Plasma adiponectin and adiponectin receptor (AdipoR1) in muscle are down-regulated in obesity. Analysis of muscle-specific AdipoR1 knockout mice revealed the pivotal role of adiponectin/AdipoR1 in the regulation of mitochondrial biogenesis via AMPK- and SIRT1 ...
T, Kadowaki, T, Yamauchi, H, Waki, M, Iwabu, M, Okada-Iwabu, M, Nakamura   +5 more
openaire   +2 more sources

Relationship of serum adiponectin and resistin to glucose intolerance and fat topography in south-Asians [PDF]

, 2006
Objectives South-Asians have lower adiponectin levels compared to Caucasians. It was not clear however, if this intrinsic feature is related to aspects of glucose metabolism.
Chetty Raja, McTernan Phillip G, Hanif Wasim, Kumar Sudhesh, A H Barnett, Barnett A H, Kumar, Sudhesh, Chetty, Raja, Nasser M Al-Daghri, Raja Chetty, Sudhesh Kumar, McTernan, P. G., Wasim Hanif, Barnett, A. H., Phillip G McTernan, Wasim, Hanif, Al-Daghri, Nasser M., Al-Daghri Nasser M   +17 more
core   +1 more source

A novel enzyme-linked immunosorbent assay specific for high-molecular-weight adiponectin

Journal of Lipid Research, 2006
Human plasma contains at least three forms of adiponectin: a trimer, a hexamer, and a high-molecular-weight (HMW) multimer. We purified HMW adiponectin from human plasma using its affinity to gelatin and obtained monoclonal antibodies against it.
Yasuko Nakano, Sachiko Tajima, Ai Yoshimi, Haruyo Akiyama, Motoo Tsushima, Toshihiro Tanioka, Takaharu Negoro, Motowo Tomita, Takashi Tobe   +8 more
doaj   +1 more source

Adiponectin/adiponectin receptor in disease and aging

npj Aging and Mechanisms of Disease, 2015
AbstractAdipocytes are not merely organs for energy conservation but endocrine organs secreting a wide array of physiologically active substances, i.e., adipokines. Of these adipokines, adiponectin is known to exert anti-diabetic and anti-atherosclerotic effects via adiponectin receptors (AdipoR)s, AdipoR1 and AdipoR2.
Iwabu, Masato, Okada-Iwabu, Miki, Yamauchi, Toshimasa, Kadowaki, Takashi   +3 more
openaire   +2 more sources

Dimerization of adiponectin receptor 1 is inhibited by adiponectin [PDF]

Journal of Cell Science, 2010
AdipoR1 and AdipoR2 are newly discovered members of the huge family of seven-transmembrane receptors, but both receptors are structurally and functionally different from G-protein-coupled receptors. Little is known about the oligomerization of the AdipoRs.
David, Kosel, John T, Heiker, Cathleen, Juhl, Cornelia M, Wottawah, Matthias, Blüher, Karin, Mörl, Annette G, Beck-Sickinger   +6 more
openaire   +2 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source