Results 21 to 30 of about 99,913 (245)

Role of the adiponectin binding protein, T-cadherin (Cdh13), in allergic airways responses in mice. [PDF]

PLoS ONE, 2012
Adiponectin is an adipose derived hormone that declines in obesity. We have previously shown that exogenous administration of adiponectin reduces allergic airways responses in mice.
Alison S Williams, David I Kasahara, Norah G Verbout, Alexey V Fedulov, Ming Zhu, Huiqing Si, Allison P Wurmbrand, Christopher Hug, Barbara Ranscht, Stephanie A Shore   +9 more
doaj   +1 more source

A randomized trial of selenium supplementation and risk of type-2 diabetes, as assessed by plasma adiponectin [PDF]

, 2012
Background: Evidence that selenium affects the risk of type-2 diabetes is conflicting, with observational studies and a few randomized trials showing both lower and higher risk linked to the level of selenium intake and status. We investigated the effect
Steinbrenner, Holger, Eliseo Guallar, Roberto Pastor-Barriuso, Stranges, S, Steinbrenner Holger, Blundell-Pound, G, Eliseo Guallar (27363), Gabrielle Blundell-Pound, Pastor-Barriuso, R, Margaret P Rayman, Pastor-Barriuso, Roberto, Blundell-Pound Gabrielle, Rayman, Margaret, Blundell-Pound, Gabrielle, Holger Steinbrenner, Stranges, Saverio, Roberto Pastor-Barriuso (62759), Gabrielle Blundell-Pound (135140), Stranges Saverio, Guallar, E, Guallar, Eliseo, Saverio Stranges, Rayman, Margaret P, Pastor-Barriuso, R., Holger Steinbrenner (135147), Steinbrenner, H, Rayman, MP, Saverio Stranges (73786), Pastor-Barriuso Roberto, Margaret P. Rayman (135136), Rayman Margaret P., Guallar Eliseo   +31 more
core   +2 more sources

Plasma omentin levels are inversely associated with atherosclerosis in type 2 diabetes patients with increased plasma adiponectin levels: a cross-sectional study

Cardiovascular Diabetology, 2019
Background Omentin and adiponectin are among the anti-inflammatory and anti-atherogenic adipokines that have potentially beneficial effects on cardiovascular disorders.
Masami Nishimura, Tomoaki Morioka, Mariko Hayashi, Yoshinori Kakutani, Yuko Yamazaki, Masafumi Kurajoh, Katsuhito Mori, Shinya Fukumoto, Atsushi Shioi, Tetsuo Shoji, Masaaki Inaba, Masanori Emoto   +11 more
doaj   +1 more source

Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes

Cardiovascular Diabetology, 2006
Background Systemic adiponectin is reduced in patients with cardiovascular disease (CVD) and low adiponectin may contribute to the pathogenesis of atherosclerosis.
Maier Kevin, Schäffler Andreas, Eggenhofer Elke, Wehrwein Gabriele, Weigert Johanna, Neumeier Markus, Abke Sabine, Aslanidis Charalampos, Schölmerich Jürgen, Buechler Christa   +9 more
doaj   +1 more source

Total and High Molecular Weight Adiponectin Levels and Prediction of Cardiovascular Risk in Diabetic Patients

International Journal of Endocrinology, 2015
The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM).
Dagmar Horáková, Kateřina Azeem, Radka Benešová, Dalibor Pastucha, Vladimír Horák, Lenka Dumbrovská, Arnošt Martínek, Dalibor Novotný, Zdeněk Švagera, Milada Hobzová, Dana Galuszková, Vladimír Janout, Sandra Doněvská, Jana Vrbková, Helena Kollárová   +14 more
doaj   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Adiponectin forms a complex with atherogenic LDL and inhibits its downstream effects

Journal of Lipid Research, 2021
Adiponectin, an adipocyte-derived protein, has antiatherogenic and antidiabetic effects, but how it confers the atherogenic effects is not well known.
Akemi Kakino, Yoshiko Fujita, Liang-Yin Ke, Hua-Chen Chan, Ming-Hsien Tsai, Chia-Yen Dai, Chu-Huang Chen, Tatsuya Sawamura   +7 more
doaj   +1 more source

The association of adiponectin gene expression and serum levels with susceptibility to peripheral polyneuropathy in Egyptian patients by women with hypothyroidism

The Egyptian Journal of Internal Medicine, 2019
Background Hypothyroidism has numerous comorbidities including degenerative neurological disease and insulin resistance. Adiponectin is an adipokine secreted by adipose tissue with insulin-sensitizing, anti-inflammatory, and antioxidant properties.
Nearmeen M Rashad, Mohamed S.S Saad, Bothina M Ramadan, Shereen M El Shabrawy   +3 more
doaj   +1 more source