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Cardioprotection by Adiponectin [PDF]
Trends in Cardiovascular Medicine, 2006 Obesity-related disorders are closely associated with the pathogenesis of cardiovascular disease. Adiponectin is a circulating adipose tissue-derived hormone that is down-regulated in obese individuals. Hypoadiponectinemia has been identified as an independent risk factor for type 2 diabetes, coronary artery disease, and hypertension, and experimental ...Noriyuki, Ouchi, Rei, Shibata, Kenneth, Walsh +2 moreopenaire +2 more sourcesAdiponectin [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 The obesity pandemic will likely have a significant impact on the global incidence of cardiovascular disease. Although the mechanisms linking obesity and cardiovascular disease are unclear, recent studies have implicated the adipocyte as a potentially important mediator of vascular complications.Peter F. Bodary, Daniel T. Eitzman +6 more sourcesTreatment-Induced Changes in Plasma Adiponectin Do Not Reduce Urinary Albumin Excretion in the Diabetes Prevention Program Cohort. [PDF]
PLoS ONE, 2015 BACKGROUND AND OBJECTIVES:Molecular data suggests that adiponectin may directly regulate urinary albumin excretion. In the Diabetes Prevention Program (DPP) we measured adiponectin and albuminuria before and after intervention, and we previously reported Kieren J Mather, Qing Pan, William C Knowler, Tohru Funahashi, George A Bray, Richard Arakaki, Bonita Falkner, Kumar Sharma, Barry J Goldstein, DPP Research Group +9 moredoaj +1 more sourceAdiponectin [PDF]
Circulation Research, 2016 Adiponectin is the most adipocyte-specific of all secretory factors described to date. Despite its exclusive expression at the level of the fat cell, adiponectin concentrations in plasma are generally inversely proportional to fat mass.1,2 More detailed studies reveal that it is not fat mass, but rather fat quality that is the driving force for ...Aslan T, Turer, Philipp E, Scherer +5 more sourcesAdiponectin and Hypertension [PDF]
American Journal of Hypertension, 2011 Adipose tissue secretes a variety of bioactive molecules, also known as adipocytokines or adipokines. Obesity, in particular, visceral fat accumulation, is implicated in the dysregulated secretion of adipocytokines, which can contribute to the development of metabolic syndrome and cardiovascular diseases.Koji, Ohashi, Noriyuki, Ouchi, Yuji, Matsuzawa +2 moreopenaire +2 more sourcesLow adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques. [PDF]
, 2009 Atherosclerosis is the primary cause of coronary artery disease (CAD). There is increasing recognition that lesion composition rather than size determines the acute complications of atherosclerotic disease.Lebherz Corinna, Renee Stark, Christoph Becker, Stark, R.G., Stark, Renee, Tittus, Janine, Lehrke Michael, Lebherz, C., Greif, Martin, Greif Martin, Broedl Uli C., Reiser, M., Stark Renee, Reiser, Maximilian, Ziegler, Franz von, Alexander W Leber, Göke, B., Parhofer, K.G., Lebherz, Corinna, Alexander Becker, Leber, A.W., Leber, Alexander W., Michael Lehrke, Corinna Lebherz, Lehrke, Michael, Greif, M., von Ziegler Franz, Parhofer Klaus G., von Ziegler, A., Göke, Burkhard, Parhofer, Klaus G., Janine Tittus, Becker, C., Becker Alexander, Broedl, U.C., Reiser Maximilian, Broedl, Uli C., Martin Greif, Klaus G Parhofer, Tittus, J., Tittus Janine, Burkhard Göke, Göke Burkhard, Becker, F., Becker, Alexander, Maximilian Reiser, Uli C Broedl, Becker, Christoph, Becker Christoph, Leber Alexander W., Franz von Ziegler, Lehrke, M. +51 morecore +1 more sourceA Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels [PDF]
, 2009 The adipocyte-derived protein adiponectin is highly heritable and inversely associated with risk of type 2 diabetes mellitus (T2D) and coronary heart disease (CHD). We meta-analyzed 3 genome-wide association studies for circulating adiponectin levels (n =Stewart, A.F.R., Stewart, AFR, O'Rahilly, S. (Stephen), Epstein, S.E., Pastinen, Tomi, Samani, NJ, O'Rahilly, S., Abecasis, Gonçalo R., Witteman, JC, Langenberg Claudia, Hall, A.S. (Alistair), Beate Glaser, Kijoung Song, Hengstenberg, Christian, Stephen E Epstein, Ruth J. F. Loos, Evans, D, Daniel J Rader, Witteman, J., Wichmann, H.-E., Willenborg, C., Toshiko Tanaka, Mary-Susan Burnett, Stark, K, Hingorani Aroon, König, Inke R, Langenberg, C, Samani, N., Van Duijn, C.M., Stark, K. (Klaus), Peter Vollenweider, Stark Klaus, Willenborg, C. (Christina), Robert K. Semple, Evans, D., Davey Smith George, Van Duijn, CM, Richards, J.B., Erdmann Jeanette, Loos, Ruth J F, Grassl, M., Josephine M. Egan, Davey Smith, George, Perry, John R. B., Wichmann, H.E., Frayling, Timothy M., Sladek, R. (Rob), Wichmann, H.E. (Heinz Erich), Barter Phil, Stewart Alexandre F. R., Mooser, Vincent, Waeber Gerard, John R Thompson, Vollenweider Peter, Reinhard, W, Ricketts Sally L., Waterworth, D. (Dawn), Meigs, J., Stark, Klaus, Davey Smith, G., Wichmann, H-Erich, Willenborg, Christina, Melzer, D, Pastinen, T., Reilly Muredach P., Rocha, Nuno, Hivert, MF, Thompson, J., Sattar, N, Smith, GD, Barter, P., König, I.R. (Inke), Winogradow, J, Meigs, JB, Stewart, Alexandre F.R., Reinhard, W. (Wibke), Semple, Robert K.; id_orcid, Nicholas John Timpson, Hall, AS, Ferrucci, L. (Luigi), Hivert, M., Scott Grundy, Christina Willenborg, ?, ?, Naveed Sattar, Witteman, Jaquelin C. M, Hall, A., Duijn, Cornelia, Florez, Jose, Sladek, R, Van Duijn Cornelia M., Saxena, R, Reilly, Muredach P., Soranzo, N. (Nicole), Melzer, David, Mahley Robert, Glaser, B, Prokopenko, Inga, Christian Hengstenberg, Schunkert, H, Dupuis, Josee, Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Aulchenko, Y, Koenig, Inke R., George Davey Smith, Loos, Ruth J.F., Thompson, JR, Frayling Timothy M., Barter, Phil, Deloukas Panos, Aulchenko Yurii, Sladek, Robert, Hengstenberg, C. (Christian), Wareham, N.J., Schunkert, H., Marie-France Hivert, Glaser Beate, John R B Perry, Reilly, M.P. (Muredach), Nicholas J Wareham, Claudia Langenberg, Timothy M, Rader Daniel J., Thompson, John R, McPherson, R. (Ruth), Erdmann, Jeanette, Spector, T., Vincent Mooser, Thompson, John R., O'Rahilly, Stephen, Loos, Ruth J. F., Josée Dupuis, Rader, D.J. (Daniel), Burling, K.A. (Keith), Tim D Spector, Ferrucci, L, Erdmann, J., Jose C. Florez, Konig, IR, Loos, RJF, Reilly, M., Tomi Pastinen, Dupuis, J, Luigi Ferrucci, Burnett, M., McPherson, R, Reilly, MP, Alexandre F R Stewart, H-Erich Wichmann, Brent Richards, J., Deloukas, P., Inke R. König, Egan, JM, Hivert Marie-France, Ferrucci Luigi, Mooser, V. (Vincent), Erdmann, J, Keith Burling, Grundberg, E, Burling, K, Frayling, T.M. (Timothy), Muredach P. Reilly, Grundy, S.M. (Scott), Kesaniemi, Y Antero, Burnett, MS, Waterworth, Dawn, Wareham, NJ, Consortium, GIANT, Waterworth, D, Egan, J., Frayling, TM, Waterworth, D., Perry, J.R.B. (John), Janina Winogradow, Meigs, James B., Evans, David, Martina Grassl, Waeber, Gerard, Ruth J F Loos, Semple, Robert K., Witteman Jaquelin C. M., Wareham, N., Samani, N.J. (Nilesh), Winogradow, Janina, Grundy, S, Rader, D., Cornelia M. Van Duijn, Deloukas, Panos, Rocha, N. (Nuno), Prokopenko Inga, Wareham, Nicholas J., Grundberg Elin, Van Duijn, C., Grundy, Scott, Barter, P. (Phil), Deanfield, J., Meigs, J.B., Tikka-Kleemola, P. (Päivi), Perry, J.R.B., Hengstenberg Christian, McPherson Ruth, Rader, DJ, Epstein Stephen E., Burnett, Mary-Susan, Smith, A.V. (Davey), Egan, J.M., Hivert, Marie-France, Burnett Mary-Susan, Witteman, Jaquelin C M, Willenborg, C, James B Meigs, Timpson Nicholas John, Alistair S Hall, Vollenweider, P, Stewart, Alexandre F. R., Hingorani, A, Soranzo Nicole, Dupuis, J. (Josée), Mahley, R, Spector, TD, Elin Grundberg, Semple, R.K., Grassl, M. (Martina), Tanaka, T, Aulchenko, Y.S. (Yurii), Grundberg, E. (Elin), Stewart, A.F.R. (Alexandre), GIANT Consortium, Burnett, M.-S., Panos Deloukas, Consortium, G., Dupuis Josée, Ferrucci, L., Robert Mahley, Waterworth Dawn, David Melzer, Richards, J Brent, Deanfield, John, Reinhard Wibke, Tanaka, T., Kesaniemi, YA, Deloukas, P, Winogradow, J., Florez Jose C., Reinhard, W., Devaney, J., Glaser, B., Song, K. (Kijoung), Ruth McPherson, Meigs, J.B. (James), Kesaniemi, Y., Tanaka Toshiko, Kesaniemi, Y. Antero, Reinhard, Wibke, Josephine M Egan, Hall, Alistair S., Samani, Nilesh J., Prokopenko, I. (Inga), Song, K, Langenberg, Claudia, Vollenweider, P., Winogradow, J. (Janina), Waeber, G. (Gérard), Sattar Naveed, Pastinen, T, Ferrucci, Luigi, Soranzo, N, Sladek Robert, Ricketts, S.L. (Sally), Wibke Reinhard, Sattar, Naveed, O'Rahilly Stephen, Spector, Tim D., Jeanette Erdmann, Richards, J.B. (Brent), Schunkert Heribert, Grundberg, Elin, Burnett, M.S., Rocha Nuno, Devaney Joseph, Florez, Jose C, Egan Josephine M., Hingorani, Aroon, Egan, Josephine M., Phil Barter, Hengstenberg, C, Inga Prokopenko, Stark, K., Hingorani, A., Erdmann, J. (Jeanette), Joseph Devaney, Timothy M Frayling, Frayling, T., Epstein, SE, J. Brent, Thompson, J.R., Perry, J., Samani, N.J., Rader, Daniel J., David Evans, Soranzo, N., Epstein, S., Waeber, G., Pastinen, T. (Tomi), Winogradow Janina, Glaser, Beate, Perry, JR, Wichmann, HE, Florez, J.C., Epstein, S.E. (Stephen), Wichmann, H., Semple Robert K., Sladek, R., Alistair S. Hall, Davey Smith, G, Y Antero Kesaniemi, Gerard Waeber, Thompson, J.R. (John), Perry, John R.B., Wichmann H-Erich, Egan, Josephine M, Richards, J. Brent, Semple, Robert K, Kesaniemi, Y.A. (Antero), Tanaka, T. (Toshiko), Saxena Richa, Egan, J.M. (Josephine), Saxena, Richa, Florez, J.C. (Jose), Burling Keith, Mooser Vincent, Timpson, Nicholas John, Van Duijn, Cornelia M., Timpson, NJ, Ricketts, SL, Epstein, Stephen E., Spector Tim D., Semple, R., Aulchenko, Yurii S., Nilesh J. Samani, Rocha, N, Devaney, Joseph, Prokopenko, I, Thompson John R., Florez, J., Richards J. Brent, Yurii Aulchenko, Aulchenko, Y., Saxena, R., Samani Nilesh J., Semple, RK, Mooser, V, Sattar, N. (Naveed), Ricketts, Sally L, Song, K., Grundberg, E., Langenberg, C., Ricketts, S., J. Brent Richards, Muredach P Reilly, Florez, JC, Smith, George Davey, Spector, T.D. (Timothy), Cornelia M Van Duijn, Kesaniemi, Y.A., Vollenweider, Peter, Saxena, R. (Richa), Perry, JRB, Wareham Nicholas J., John Deanfield, Prokopenko, I., Soranzo, Nicole, Burling, Keith, Witteman, JCM, Rader, D.J., Melzer David, Grassl, M, König, I.R., Perry John R. B., Stewart, A., Devaney, J. (Joseph), Song Kijoung, Sattar, N., Witteman, Jaquelin C.M., Mahley, R., Dawn Waterworth, John R. Thompson, Melzer, D. (David), Melzer, D., Evans, D.M. (David), Loos, R., Hingorani, A. (Aroon), Re F. R. Stewart, Mooser, V., Stephen E. Epstein, Pastinen Tomi, Richa Saxena, Mahley, R. (Robert), König, I., König, Inke R., Timpson, N., Nuno Rocha, Nicole Soranzo, Hengstenberg, C., Grundy Scott, Hivert, M.-F., Loos, RJ, O'Rahilly, S, Sally L Ricketts, Loos Ruth J. F., Barter, P, Stewart, AF, Wichmann, Heinz-Erich, Robert K Semple, Devaney, J, Mahley, Robert, Ricketts, Sally L., Heribert Schunkert, Klaus Stark, John R. B. Perry, Deanfield John, Schunkert, H. (Heribert), McPherson, Ruth, Tanaka, Toshiko, Dupuis, J., J Brent Richards, Aroon Hingorani, Inke R König, Daniel J. Rader, Song, Kijoung, Hivert, M.-F. (Marie-France), Jaquelin C M Witteman, Grassl, Martina, Schunkert, Heribert, Spector, T.D., Loos, R.J.F., Hall, Alistair S, Grassl Martina, Waeber, G, Semple, R.K. (Robert), Hall, A.S., Grundy, S., Florez, Jose C., Witteman, Jaquelin C. M., Perry, John R B, Frayling, T.M., Y. Antero Kesaniemi, Jose C Florez, Sally L. Ricketts, Evans David, Rocha, N., Willenborg Christina, Robert Sladek, Aulchenko, Yurii, Stephen O'Rahilly, Citation Richards, Meigs, James, Kesaniemi Y. Antero, Witteman, J.C.M. (Jacqueline), Richards, J., Timpson, N.J. (Nicholas), Deanfield, J. (John), Meigs James B., Aulchenko, Yuriy, Witteman, J.C.M., Glaser, B. (Beate), Richards, JB, König Inke R., Vollenweider, P. (Peter), Burling, K., Deanfield, J, McPherson, R., Deloukas, P. (Panagiotis), Nilesh J Samani, Timpson, N.J., Langenberg, C. (Claudia), Hall Alistair S., Reilly, M.P., Jaquelin C. M. Witteman, Ricketts, S.L. +480 morecore +1 more source
