Results 11 to 20 of about 70,562 (248)
Circulation Research, 2016 Adiponectin is the most adipocyte-specific of all secretory factors described to date. Despite its exclusive expression at the level of the fat cell, adiponectin concentrations in plasma are generally inversely proportional to fat mass.1,2 More detailed studies reveal that it is not fat mass, but rather fat quality that is the driving force for ...
Aslan T, Turer, Philipp E, Scherer
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Treatment-Induced Changes in Plasma Adiponectin Do Not Reduce Urinary Albumin Excretion in the Diabetes Prevention Program Cohort. [PDF]
PLoS ONE, 2015 BACKGROUND AND OBJECTIVES:Molecular data suggests that adiponectin may directly regulate urinary albumin excretion. In the Diabetes Prevention Program (DPP) we measured adiponectin and albuminuria before and after intervention, and we previously reported
Kieren J Mather +9 more
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Age Associated Changes In Transcription Of Adiponectin, AdipoR1 And AdipoR2 Genes In Pancreas Of Rats [PDF]
Cell Journal, 2020 Objective Adiponectin has a crucial role in the function, proliferation and viability of β-cell via action of two receptors: AdipoR1 and AdipoR2. Nevertheless, age related change of Adiponectin system genes in pancreas is unclear or controversial.
Marziyeh Feyzi +3 more
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Time course of adiponectin and its relationship to psychological aspects in patients with anorexia nervosa during inpatient treatment. [PDF]
PLoS ONE, 2017 The protein hormone adiponectin promotes metabolic and psychological health. The aim of the study was to track changes in adiponectin levels in response to weight gain and to assess associations between adiponectin and psychological aspects in patients ...
Magdalena Buckert +8 more
doaj +1 more source
Circulating High-Molecular-Weight (HMW) Adiponectin Level Is Related with Breast Cancer Risk Better than Total Adiponectin: A Case-Control Study. [PDF]
PLoS ONE, 2015 The level of total adiponectin, a mixture of different adiponectin forms, has been reported associated with breast cancer risk with inconsistent results. Whether the different forms play different roles in breast cancer risk prediction is unclear.
Ming-ming Guo +32 more
doaj +1 more source
Adiponectin and Hypertension [PDF]
American Journal of Hypertension, 2011 Adipose tissue secretes a variety of bioactive molecules, also known as adipocytokines or adipokines. Obesity, in particular, visceral fat accumulation, is implicated in the dysregulated secretion of adipocytokines, which can contribute to the development of metabolic syndrome and cardiovascular diseases.
Koji, Ohashi +2 more
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Frontiers in Endocrinology, 2013 High molecular weight (HMW) adiponectin levels are reduced in humans with type 2 diabetes and insulin resistance. Similar to humans with insulin resistance, managed bottlenose dolphins (Tursiops truncatus) diagnosed with hemochromatosis (iron overload ...
Benjamin A Neely +5 more
doaj +1 more source
A novel enzyme-linked immunosorbent assay specific for high-molecular-weight adiponectin
Journal of Lipid Research, 2006 Human plasma contains at least three forms of adiponectin: a trimer, a hexamer, and a high-molecular-weight (HMW) multimer. We purified HMW adiponectin from human plasma using its affinity to gelatin and obtained monoclonal antibodies against it.
Yasuko Nakano +8 more
doaj +1 more source
Adiponectin/adiponectin receptor in disease and aging
npj Aging and Mechanisms of Disease, 2015 AbstractAdipocytes are not merely organs for energy conservation but endocrine organs secreting a wide array of physiologically active substances, i.e., adipokines. Of these adipokines, adiponectin is known to exert anti-diabetic and anti-atherosclerotic effects via adiponectin receptors (AdipoR)s, AdipoR1 and AdipoR2.
Iwabu, Masato +3 more
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Adiponectin, Adiponectin Receptors, and Epigenetic Regulation of Adipogenesis [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2011 We studied the molecular mechanism of obesity-induced insulin resistance and adipogenesis. Plasma adiponectin and adiponectin receptor (AdipoR1) in muscle are down-regulated in obesity. Analysis of muscle-specific AdipoR1 knockout mice revealed the pivotal role of adiponectin/AdipoR1 in the regulation of mitochondrial biogenesis via AMPK- and SIRT1 ...
T, Kadowaki +5 more
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