Results 41 to 50 of about 39,668 (310)
Die Rolle der Adipokine als Verlaufs- und Prognoseparameter bei der Staphylococcus aureus Bakteriämie [PDF]
, 2023 Sowohl die Sepsis als auch die immunologische Funktion des Fettgewebes stellen aufgrund ihrer Relevanz für den klinischen Alltag wichtige und aktuelle Forschungsschwerpunkte in der Medizin dar.
Möllmann, Natalie
core +1 more source
Animals, 2021 We evaluated the dietary effects of multiple probiotics in Jeju native pigs, using basal diet and multi-probiotic Lactobacillus (basal diet with 1% multi-probiotics) treatments (n = 9 each) for 3 months.
Dahye Kim +11 more
doaj +1 more source
Epigenetic Regulation of Adipokines [PDF]
International Journal of Molecular Sciences, 2017 Adipose tissue expansion in obesity leads to changes in the expression of adipokines, adipocyte-specific hormones that can regulate whole body energy metabolism. Epigenetic regulation of gene expression is a mechanism by which cells can alter gene expression through the modifications of DNA and histones.
Pham, Tho X., Lee, Ji-Young
openaire +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Adipokines in Liver Cirrhosis [PDF]
International Journal of Molecular Sciences, 2017 Liver fibrosis can progress to cirrhosis, which is considered a serious disease. The Child-Pugh score and the model of end-stage liver disease score have been established to assess residual liver function in patients with liver cirrhosis. The development of portal hypertension contributes to ascites, variceal bleeding and further complications in these
Buechler, Christa +3 more
openaire +2 more sources
A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion
, 2021 Adipocytes sense systemic nutrient status and systemically communicate this information by releasing adipokines. The mechanisms which couple nutritional state to adipokine release are unknown. Here, we investigated how Unpaired 2 (Upd2), a structural and
Housden, Benjamin E. +4 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan +10 more
wiley +1 more source
Journal of Lipid Research, 2015 Adipocyte fatty acid binding protein 4, aP2, contributes to the pathogenesis of several common diseases including type 2 diabetes, atherosclerosis, fatty liver disease, asthma, and cancer.
Meric Erikci Ertunc +7 more
doaj +1 more source
The Emerging Role of Intelectin-1 in Cancer
Frontiers in Oncology, 2022 BackgroundIntelectin (ITLN) is an adipokine with two homologs—ITLN1 and ITLN2—that has various physiological functions. Studies analyzing the relationship between ITLN and cancer are focused on ITLN1; the available literature on ITLN2 and cancer is ...
D. Robert Paval +3 more
doaj +1 more source