Results 61 to 70 of about 36,782 (313)

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

Adipokine als metabolische Prädiktoren [PDF]

, 2019
Adipokine sind Proteine, die aus dem Fettgewebe freigesetzt werden. Viele dieser Fettzell-sezernierten Proteine sind bei Adipositas dysreguliert und beeinflussen das Risiko für kardiometabolische Folgeerkrankungen. Die vorliegende Arbeit untersucht daher
Ebert, Thomas
core   +1 more source

Die Adipokine Adiponectin und Leptin [PDF]

, 2017
ZusammenfassungDas Fettgewebe ist ein endokrines Organ und bildet eine ganze Reihe von Fettgewebshormonen, die als Adipokine bezeichnet werden. Zu ihnen gehören als Leitsubstanzen Adiponectin und
Karlheiz Schmidt, Wolfgang Bayer
core   +1 more source

Pregnancy-induced hypertension, preterm birth, and cord blood adipokine levels [PDF]

, 2020
Maternal hypertension may alter physiological parameters, dysregulating the release of hormones such as adipokines, thus influencing the fetal growth course.
Peixoto-Filho, Fernando Maia, Moreira, Maria Elisabeth Lopes, Costa, Ana Carolina Carioca da, Méio, Maria Dalva Barbosa Baker, Gonzalez, Sayonara, Magalhães, Elizabeth Soares da Silva   +5 more
core   +1 more source

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

Journal of Lipid Research, 2015
Adipocyte fatty acid binding protein 4, aP2, contributes to the pathogenesis of several common diseases including type 2 diabetes, atherosclerosis, fatty liver disease, asthma, and cancer.
Meric Erikci Ertunc, Jørgen Sikkeland, Federico Fenaroli, Gareth Griffiths, Mathew P. Daniels, Haiming Cao, Fahri Saatcioglu, Gökhan S. Hotamisligil   +7 more
doaj   +1 more source

The Emerging Role of Intelectin-1 in Cancer

Frontiers in Oncology, 2022
BackgroundIntelectin (ITLN) is an adipokine with two homologs—ITLN1 and ITLN2—that has various physiological functions. Studies analyzing the relationship between ITLN and cancer are focused on ITLN1; the available literature on ITLN2 and cancer is ...
D. Robert Paval, Thomas George Di Virgilio, Richard J. E. Skipworth, Iain J. Gallagher   +3 more
doaj   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Role of adipokines in sarcopenia

Chinese Medical Journal, 2023
Abstract Sarcopenia is an age-related disease that mainly involves decreases in muscle mass, muscle strength and muscle function. At the same time, the body fat content increases with aging, especially the visceral fat content.
Wenhao Lu, Wenjie Feng, Jieyu Lai, Dongliang Yuan, Wenfeng Xiao, Yusheng Li, Ningning Wang   +6 more
openaire   +3 more sources

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Fatores associados aos níveis séricos de adiponectina em portadores de cirrose hepática [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2014.Introdução: Apesar de os baixos níveis de adiponectina serem relacionados à maior progressão ...
Silva, Telma Erotides da
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