Results 61 to 70 of about 52,905 (310)
Equine models in translational medicine: A comparative approach to human health
Animal Models and Experimental Medicine, EarlyView.This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
Journal of Lipid Research, 2015 Adipocyte fatty acid binding protein 4, aP2, contributes to the pathogenesis of several common diseases including type 2 diabetes, atherosclerosis, fatty liver disease, asthma, and cancer.
Meric Erikci Ertunc +7 more
doaj +1 more source
The Emerging Role of Intelectin-1 in Cancer
Frontiers in Oncology, 2022 BackgroundIntelectin (ITLN) is an adipokine with two homologs—ITLN1 and ITLN2—that has various physiological functions. Studies analyzing the relationship between ITLN and cancer are focused on ITLN1; the available literature on ITLN2 and cancer is ...
D. Robert Paval +3 more
doaj +1 more source
Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences [PDF]
, 2010 Lipoatrophy and metabolic complications of treatment of human immunodeficiency virus (HIV) infection may share common associations with adipose tissue pathology and inflammation.
Hammond, E.L., McKinnon, E., Nolan, D.
core +2 more sources
Adipokines in rheumatoid arthritis [PDF]
Advances in Rheumatology, 2018 Rheumatoid arthritis affects millions of people worldwide and is considered a chronic multisystem disease whose causes are unknown. In general, the main objective of rheumatoid arthritis treatment is to improve the quality of life of patients by relieving pain, maintaining or improving functional capacity, preventing thus, disability.
Elis Carolina de Souza Fatel +3 more
openaire +3 more sources
Obesity, adipokines and COVID‐19 [PDF]
European Journal of Clinical Investigation, 2020 The SARS-CoV-2 pandemic has led to worldwide research aiming to identify the risk factors for developing critical illness and mortality caused by COVID-19. It quickly became apparent that besides older age, obesity is one of the most important risk factors for a more severe course of COVID-19, although the mechanisms remain largely unknown [1-3 ...
Post, Adrian +2 more
openaire +2 more sources
The complex interactions between obesity, metabolism and the brain [PDF]
, 2019 Obesity is increasing at unprecedented levels globally, and the overall impact ofobesity on the various organ systems of the body is only beginning to be fullyappreciated. Because of the myriad of direct and indirect effects of obesity causingdysfunction
Keller, Jeffrey Neil +1 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola +14 more
wiley +1 more source
Frontiers in Endocrinology, 2021 BackgroundPremature/low-birth-weight infants are at significant risk of metabolic diseases in adulthood, which may be related to the levels of fetal adipokine.
Luyan Han +7 more
doaj +1 more source
Regulation of tissue crosstalk by skeletal muscle-derived myonectin and other myokines. [PDF]
, 2012 The integrated control of animal physiology requires intimate tissue crosstalk, a vital task mediated by circulating humoral factors. As one type of these factors, adipose tissue-derived adipokines have recently garnered attention as important regulators
Seldin, Marcus M, Wong, G William
core +1 more source