Results 231 to 240 of about 39,956 (312)

Precision Medicine in Overlap Syndrome (COPD-Obstructive Sleep Apnea): From Phenotypes and Endotypes to Treatable Traits. [PDF]

Adv Respir Med
Afloarei CA, Zabara Antal A, Toma D, Pintilie AL, Pitusac G, Tiron R, Birladeanu T, Zaharia T, Crisan Dabija R.   +8 more
europepmc   +1 more source

Leptin–cholesterol crosstalk in pregnancy: Mechanistic implications for placental function and cardiometabolic programming

Experimental Physiology, EarlyView.
Abstract Pregnancy requires the coordinated maternal reorganization of lipid and endocrine pathways to sustain fetal growth and anticipate neonatal nutrition. Leptin, produced by adipose tissue and the placenta, acts as an integrative signal linking maternal energy status with trophoblast function and vascular adaptation, while cholesterol provides ...
Julio Flores, Diego Gumera, Andreina Arias, Cristián A. Amador, María José Yañez   +4 more
wiley   +1 more source

Musculoskeletal decay and bone–muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures

Experimental Physiology, EarlyView.
Abstract Older adults experience a markedly increased risk of falls and fractures following hospital discharge, largely due to the rapid musculoskeletal deterioration associated with bed rest. Although age‐related muscle and bone loss typically develops gradually, acute physical inactivity accelerates key biological processes underlying sarcopenia and ...
Julia Margarita Reyes, Guy Hajj‐Boutros, Dounia Rouabhia, José Morais, Felipe Salech, Gustavo Duque   +5 more
wiley   +1 more source

Adipokine-mediated metabolic responses across BMI in acute myocardial infarction. [PDF]

BMC Cardiovasc Disord
Sunita S, Syamsunarno MRAA, Akbar MR, Nugrahani AD, Sylviana N, Nugraha GI, Ghozali M, Achmad TH.   +7 more
europepmc   +1 more source

Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring

Experimental Physiology, EarlyView.
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas, Cristián A. Amador, Susana Contreras‐Duarte   +2 more
wiley   +1 more source

Impact of Body Size on Preclinical Type 1 Diabetes Development and Progression. [PDF]

Diabetes Care
Gupta RM, Ismail HM, Siller AF, Pesikoff J, Devaraj S, Balasubramanyam A, Redondo MJ.   +6 more
europepmc   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Causal role of adipose tissue-derived adipokines in the pathogenesis of heart failure with preserved ejection fraction: experimental demonstration as the basis for clinical targeting. [PDF]

Eur Heart J
Packer M.
europepmc   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Adiposity-dependent adipokine-immunoglobulin interplay in mature breast milk. [PDF]

Front Endocrinol (Lausanne)
Lis-Kuberka J, Humaj-Grysztar M, Apanasewicz A, Matyas M, Ziomkiewicz A, Orczyk-Pawiłowicz M.   +5 more
europepmc   +1 more source