Results 241 to 250 of about 39,956 (312)

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2089-2101, October 2026.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Gene expression of adipokines in placentas of cows from Northeastern Brazil with and without hyperketonemia and their interactions with metabolic biomarkers. [PDF]

Trop Anim Health Prod
da Conceição ÂI, de Barros Dantas JVJ, de Mendonça CL, de Paula Cajueiro JF, Souto RJC, Pinto L, de Araújo Gonçalves DN, de Souza PRE, Afonso JAB, Soares PC.   +9 more
europepmc   +1 more source

Analysis of the Mediating Role of Cytokines in the Relationship Between Nonalcoholic Fatty Liver Disease and Cognitive Impairment After Ischemic Stroke

Brain and Behavior, Volume 16, Issue 10, October 2026.
This article reveals the mediating role of cytokine levels between non‐alcoholic fatty liver disease and post‐stroke cognitive impairment, providing new therapeutic targets for post‐stroke cognitive dysfunction. Abstract Objective To explore whether nonalcoholic fatty liver disease (NAFLD) is associated with poststroke cognitive impairment (PSCI) and ...
Xin Du, Jingwei Li
wiley   +1 more source

Current and Future Perspectives on Adipo-Oncology: Roles of Adipocytes in Local and Systemic Tumor Regulation. [PDF]

Pathol Int
Sato S.
europepmc   +1 more source

Cancer and Hypertension: Shared Mechanisms, Treatment Interactions, and Clinical Management

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Cancer and hypertension (HTN) frequently coexist, and their relationship is increasingly recognized as a clinically relevant intersection between oncology and cardiovascular medicine. However, the extent to which this association reflects shared risk factors, common biological mechanisms, or treatment‐related effects remains incompletely ...
Peizhi Jia, Daxin Chen, Jingting Wang, Yupei Guo, Jinhong Liu, Jiumao Lin   +5 more
wiley   +1 more source

Combined Aerobic-Resistance Training and Taurine Supplementation Reduce Asprosin and Elevate Spexin in Men with Obesity: A 12-Week Supplement-Blinded, Randomized Controlled Trial. [PDF]

Nutrients
Saedmocheshi S, Dhahbi W, Saeidi A, Rahmani A.   +3 more
europepmc   +1 more source

Menopausal Stage–Specific Associations of Body Fat Content and Total Body Water With Vasomotor Symptoms

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Associations of adiposity and total body water with vasomotor symptoms varied according to menopausal stage. Divergent relationships observed across body composition measures suggest that distinct physiological mechanisms may underlie vasomotor symptoms during the menopausal transition and postmenopause.
Katarzyna Górecka, Monika Krzyżanowska
wiley   +1 more source

Endothelial Dysfunction and Obesity: New Diagnostic and Therapeutic Strategies. [PDF]

Int J Mol Sci
Giglio RV, Stankovic S, Patti AM, Rizzo M, Ciaccio M.   +4 more
europepmc   +1 more source

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha, Richa Gill, Sergio Crovella, Haissam Abou‐Saleh, Sahar Isa Da'as   +4 more
wiley   +1 more source

Adipokine profile in acute heart failure: associations with natriuretic response and prognosis. [PDF]

ESC Heart Fail
Biegus J, Tymków R, Iwanek G, Zymliński R, Guzik M, Hurkacz M, Sopyla W, Gajewski P, Ponikowski P.   +8 more
europepmc   +1 more source