Results 261 to 270 of about 39,956 (312)

Mapping Fatty Acid Composition in the Human Knee: Short‐Term Repeatability at 3T

open access: yesJournal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1066-1076, October 2026.
ABSTRACT Background Alterations in periarticular lipid composition are implicated in musculoskeletal diseases, yet short‐term reliability of MRI‐based triglyceride composition mapping in the knee is not fully established. Purpose To evaluate 1‐week repeatability of proton‐density fat fraction (PDFF) and triglyceride fatty‐acid composition—saturated ...
Dimitri Martel   +8 more
wiley   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng   +4 more
wiley   +1 more source

Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley   +1 more source

Adipocyte‐Derived KIF13B Aggravates Obesity‐Associated Metabolic Dysfunction via LRP1/PPARγ Signaling

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Adipocyte‐derived KIF13B promotes LRP1 localization and nuclear LRP1–PPARγ transcriptional activity, thereby enhancing adipogenic gene expression, lipid accumulation, and obesity‐associated metabolic dysfunction. Adipocyte‐specific Kif13b deletion disrupts this LRP1/PPARγ axis, suppresses adipogenic programming, reduces adipose expansion, and protects ...
Guolin Miao   +19 more
wiley   +1 more source

Identification of alpha1-oleate as a potent regulator of adipokine-dependent metabolism, in bladder cancer tissue. [PDF]

open access: yesCancer Metab
Haq F   +9 more
europepmc   +1 more source

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