Results 101 to 110 of about 76,948 (302)
iMetaOmics, EarlyView.This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian +7 more
wiley +1 more source
Renin-Angiotensin-Aldosterone System, Glucose Metabolism and Incident Type 2 Diabetes Mellitus: MESA. [PDF]
, 2018 Background Mechanistic studies suggest that aldosterone impairs glucose metabolism. We investigated the cross-sectional associations of aldosterone and plasma renin activity with fasting plasma glucose, insulin resistance ( IR ), β-cell function, and ...
Allison, Matthew A +5 more
core +1 more source
Modulation of intestinal microbiota and immunometabolic parameters by caloric restriction and lactic acid bacteria [PDF]
, 2018 The objective of this work was to evaluate the effect of a caloric restriction diet with and without the administration of Lactobacillus fermentum CRL1446, Lactobacillus casei CRL431 and Lactococcus lactis CRL1434, on immunemetabolic parameters and the ...
Abeijon Mukdsi, Maria Claudia +5 more
core +1 more source
Adipokines and Insulin Resistance
Molecular Medicine, 2008 Obesity is associated with an array of health problems in adult and pediatric populations. Understanding the pathogenesis of obesity and its metabolic sequelae has advanced rapidly over the past decades. Adipose tissue represents an active endocrine organ that, in addition to regulating fat mass and nutrient homeostasis, releases a large number of ...
Katja, Rabe +3 more
openaire +2 more sources
iNew Medicine, EarlyView.Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang +9 more
wiley +1 more source
Adipose Tissue and Adipokines: The Association with and Application of Adipokines in Obesity
Scientifica, 2014 2014 marks the 20th anniversary of adipokines. Through the identification of leptin, our perceived understanding of adipose tissue was changed instantaneously.
Muhammad Khan, Frank Joseph
doaj +1 more source
Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy [PDF]
, 2017 Obesity increases preeclampsia risk. Adipose tissue inflammation may contribute to the clinical syndrome of pre-eclampsia. We compared adipose tissue macrophage infiltration and release of pro-inflammatory adipokines in pre-eclampsia and healthy ...
Bray, Jack +6 more
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
Adipokines and their possible role in obesity and type 2 diabetes mellitus [PDF]
Саратовский научно-медицинский журнал, 2018 The adipose tissue is the endocrine organ secreting polypeptide factors, such as adipokines, which are involved in the regulation of feeding behavior, the metabolic, endocrine and inflammatory processes and insulin sensitivity.
Kuznetsova L.A., Shpakov А.О.
doaj
Effects of adenotonsillectomy on plasma inflammatory biomarkers in obese children with obstructive sleep apnea: A community-based study. [PDF]
, 2015 BackgroundObesity and obstructive sleep apnea syndrome (OSA) are highly prevalent and frequently overlapping conditions in children that lead to systemic inflammation, the latter being implicated in the various end-organ morbidities associated with these
Alonso-Álvarez, ML +7 more
core +1 more source