Results 271 to 280 of about 75,945 (288)
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Nature Reviews Rheumatology, 2016
Adipose tissue secretes highly bioactive factors, the adipokines. Systemic levels of adipokines are often altered in the presence of inflammation. In turn, adipokines affect different tissues and cells systemically as well as locally, contributing to immunomodulatory and bone remodelling mechanisms.
Elena, Neumann +4 more
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Adipose tissue secretes highly bioactive factors, the adipokines. Systemic levels of adipokines are often altered in the presence of inflammation. In turn, adipokines affect different tissues and cells systemically as well as locally, contributing to immunomodulatory and bone remodelling mechanisms.
Elena, Neumann +4 more
openaire +2 more sources
2006
Chronic kidney disease (CKD) is now considered as one of the strongest risk factors for all cause mortality and cardiovascular events. However, the link between CKD and systemic events is unclear. The role of the kidney is primarily considered a target organ during the development of obesity as altered production of adipokines from visceral adipocytes,
Hitomi, Kataoka, Kumar, Sharma
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Chronic kidney disease (CKD) is now considered as one of the strongest risk factors for all cause mortality and cardiovascular events. However, the link between CKD and systemic events is unclear. The role of the kidney is primarily considered a target organ during the development of obesity as altered production of adipokines from visceral adipocytes,
Hitomi, Kataoka, Kumar, Sharma
openaire +2 more sources
Adipokines in Childhood Obesity
2013The worldwide increase in the prevalence of obesity in children and adolescents during the past decades, in addition to mounting evidence indicating that obesity is associated with an increased incidence of comorbidities and the risk of premature death, resulting in a high economical impact, has stimulated obesity-focused research.
Gabriel Ángel, Martos-Moreno +3 more
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Adipokines and Alzheimer's Disease
2011Alzheimer's disease pathology involves β-amyloid and tau. Various potential pharmacological targets are discussed that may be able to alleviate the accumulation of β-amyloid and tau. Possible causes of Alzheimer's disease are discussed involving impaired glucose and lipid metabolism and obesity. Adipokines may be involved in the etiology of Alzheimer's
SORTINO, Maria Angela +2 more
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Adipokines in gestational diabetes
The Lancet Diabetes & Endocrinology, 2014Gestational diabetes is characterised by glucose intolerance with onset or first recognition during pregnancy. The disease shows facets of the metabolic syndrome including obesity, insulin resistance, and dyslipidaemia. Adipokines are a group of proteins secreted from adipocytes, which are dysregulated in obesity and contribute to metabolic and ...
Mathias, Fasshauer +2 more
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Adipokines in human reproduction
Hormone Molecular Biology and Clinical Investigation, 2015Abstract Adipose tissue communicates with other central and peripheral organs by the synthesis and release of substances called adipokines. The most studied adipokine is leptin but others have been recently identified including resistin, adiponectin, chemerin, omentin and visfatin. These adipokines have a critical role in the development
Dupont, Joëlle +4 more
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Comprehensive Physiology, 2017
ABSTRACTOur understanding of adipose tissue as an endocrine organ has been transformed over the last 20 years. During this time, a number of adipocyte‐derived factors or adipokines have been identified. This article will review evidence for how adipokines acting via the central nervous system (CNS) regulate normal physiology and disease pathology.
Craig, Beall +2 more
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ABSTRACTOur understanding of adipose tissue as an endocrine organ has been transformed over the last 20 years. During this time, a number of adipocyte‐derived factors or adipokines have been identified. This article will review evidence for how adipokines acting via the central nervous system (CNS) regulate normal physiology and disease pathology.
Craig, Beall +2 more
openaire +2 more sources
Journal of Renal Nutrition, 2012
The adipose tissue has pleiotropic functions far beyond the mere storage of energy, and it secretes a number of hormones and cytokines, called adipokines, which have biological effects that impact heath and disease. Adipokines are markedly elevated in the plasma of uremic patients, mainly due to decreased renal excretion.
openaire +2 more sources
The adipose tissue has pleiotropic functions far beyond the mere storage of energy, and it secretes a number of hormones and cytokines, called adipokines, which have biological effects that impact heath and disease. Adipokines are markedly elevated in the plasma of uremic patients, mainly due to decreased renal excretion.
openaire +2 more sources