Results 81 to 90 of about 1,643 (198)

Adipokinetic hormones and their G protein-coupled receptors emerged in Lophotrochozoa [PDF]

, 2016
Most multicellular animals belong to two evolutionary lineages, the Proto– and Deuterostomia, which diverged 640–760 million years (MYR) ago. Neuropeptide signaling is abundant in animals belonging to both lineages, but it is often unclear whether there ...
Grimmelikhuijzen, Cornelis, Hauser, Frank, Kirketerp-Møller, Nikolaj, Li, Shizhong, Nielsen, Stine Vang, Skadborg, Signe K.   +5 more
core   +1 more source

New insights in Adipokinetic Hormone (AKH) precursor processing in Locusta migratoria obtained by capillary liquid chromatography-tandem mass spectrometry

Peptides, 2002
After translation, the AKH I and AKH II precursors form three dimeric constructs prior to further processing into the respective AKHs and three dimeric Adipokinetic Hormone Precursor Related Peptides or APRPs (two homodimers and one heterodimer). By capillary liquid chromatography-tandem mass spectrometry we demonstrate that the APRPs in Locusta ...
Baggerman, G, Huybrechts, J, Clynen, E, Hens, K, Harthoorn, L, Van der Horst, D, Poulos, C, De Loof, A, Schoofs, L   +8 more
openaire   +3 more sources

Characterization of Triacylglycerol Dynamics and Lipid Metabolism in the Beetle Tribolium castaneum

Archives of Insect Biochemistry and Physiology, Volume 120, Issue 3, November 2025.
Tribolium castaneum larvae accumulate triacylglycerol (TAG) during development, while adults rapidly deplete reserves post‐emergence. Under starvation, beetles prioritize protein catabolism over lipid mobilization, despite increased expression of lipolysis genes, revealing stage‐specific metabolic adaptations in this model insect.
Marcelle Pessoa‐Nascimento, Luayni Lorena Fernandes Queiroz, Pamela Verdan Pimenta do Nascimento, Fernanda Almeida‐Oliveira, David Majerowicz   +4 more
wiley   +1 more source

CAPA neuropeptides and their receptor form an anti-diuretic hormone signalling system in the human disease vector, Aedes aegypti [PDF]

, 2020
Insect CAPA neuropeptides are homologs of mammalian neuromedin U and are known to influence ion and water balance by regulating the activity of the Malpighian ‘renal’ tubules (MTs).
Ber, Lindsay Taylor, Lajevardi, Aryan, Matei, Andreea, Paluzzi, Jean-Paul, Paputsis, Christine, Sajadi, Farwa, Uyuklu, Ali, Wahedi, Azizia   +7 more
core   +1 more source

Data for the homology modelling of the red pigment-concentrating hormone receptor (Dappu-RPCHR) of the crustacean Daphnia pulex, and docking of its cognate agonist (Dappu-RPCH)

Data in Brief, 2017
The data presented in this article are related to the publication “Interaction of the red pigment-concentrating hormone of the crustacean Daphnia pulex, with its cognate receptor, Dappu-RPCHR: A nuclear magnetic resonance and modeling study” (Jackson
Graham E. Jackson, Elumalai Pavadai, Gerd Gäde, Zaheer Timol, Niels H. Andersen   +4 more
doaj   +1 more source

Characterisation and pharmacological analysis of a crustacean G protein-coupled receptor: the red pigment-concentrating hormone receptor of Daphnia pulex

Scientific Reports, 2017
This is the first pharmacological characterisation of a neuropeptide G protein-coupled receptor (GPCR) in a crustacean. We cloned the ORF of the red pigment-concentrating hormone from a German strain of Daphnia pulex (Dappu-RPCH), as well as that of the ...
Heather G. Marco, Heleen Verlinden, Jozef Vanden Broeck, Gerd Gäde   +3 more
doaj   +1 more source

Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in Drosophila. [PDF]

PLoS Genetics, 2015
LKB1 plays important roles in governing energy homeostasis by regulating AMP-activated protein kinase (AMPK) and other AMPK-related kinases, including the salt-inducible kinases (SIKs).
Sekyu Choi, Dae-Sik Lim, Jongkyeong Chung   +2 more
doaj   +1 more source

Functional characterization of hypertrehalosemic hormone receptor in relation to hemolymph trehalose and to oxidative stress in the cockroach Blattella germanica

Frontiers in Endocrinology, 2012
Hypertrehalosemic hormone (HTH) is a peptide hormone that belongs to the AKH/RPCH (adipokinetic hormone/red pigment concentrating hormone) family, which exerts pleiotropic actions related to catabolic reaction and stress response.
Jia-Hsin eHuang, Xavier eBelles, How-Jing eLee   +2 more
doaj   +1 more source

The adipokinetic hormones and their cognate receptor from the desert locust, Schistocerca gregaria: solution structure of endogenous peptides and models of their binding to the receptor [PDF]

PeerJ, 2019
Background Neuropeptides exert their activity through binding to G protein-coupled receptors (GPCRs). GPCRs are well-known drug targets in the pharmaceutical industry and are currently discussed as targets to control pest insects.
Graham E. Jackson, Elumalai Pavadai, Gerd Gäde, Niels H. Andersen   +3 more
doaj   +2 more sources

Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila [PDF]

, 2017
Multiple neuropeptides are known to regulate water and ion balance in Drosophila melanogaster. Several of these peptides also have other functions in physiology and behavior.
Davies, Shireen A., Marley, Richard, Nässel, Dick R., Zandawala, Meet   +3 more
core   +1 more source