Results 151 to 160 of about 157,661 (308)

Effect of Bariatric Surgery on Osteoarthritis‐Related Pain and Function: A Systematic Review and Meta‐Analysis

World Journal of Surgery, EarlyView.
Metabolic and bariatric surgery is associated with significant reductions in osteoarthritis diagnosis and improvements in OA‐related pain and physical function. These findings suggest that surgical weight loss may provide meaningful benefits for joint health in patients with obesity.
Mohammed Mana Mohammed Alqahtani, António Raposo, Abdullah Mohammed Saeed Alshalaan, Saeed Mohammed Saad Asiri, Jaber Salman Yazeed Alfaifi, Saleh Mohammed Saleh Alqahtani, Rawan Asad Salameh Shawabkeh, Afnan Ali Saeed Abonukhaa, Sara Ahmed Elmahadi Ahmed, Maha Hassan Ali Asiri, Mohammad Abdullah Saeed Almastoor, Ariana Saraiva, Ashwag Saleh Alsharidah, Ibrahim Yahya Al Yasin, Najim Z. Alshahrani   +14 more
wiley   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

Allergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz   +7 more
wiley   +1 more source

Alterations in Adiponectin Expression in Models of Cigarette Smoke Extract-Induced Mouse Pulmonary Emphysema and Alveolar Epithelial Cell Injury

COPD
Purpose Cigarette smoke activates lung inflammation and destruction and the development of COPD. Among various factors influenced by lung inflammation, adiponectin produced by lung epithelial cells is thought to play a significant role in regulating ...
Siriporn Vongsaiyat Siriphorn, Supitsara Thorsuwan, Julalux Thongam, Sukpattaraporn Ruangklai, Poungpetch Hussarin, Thanaporn Rungruang, Sorachai Srisuma   +6 more
doaj   +1 more source

Moderate alcohol consumption alters both leucocyte gene expression profiles and circulating proteins related to immune response and lipid metabolism in men [PDF]

Moderate alcohol consumption has various effects on immune and inflammatory processes, which could accumulatively modulate chronic disease risk. So far, no comprehensive, integrative profiling has been performed to investigate the effects of longer-term ...
Erk, M.J., van, Hendriks, H.F.J., Joosten, M.M., Pellis, E.P.M., Witkamp, R.F.   +4 more
core   +2 more sources

Relationship among the leptin-to-adiponectin ratio, systemic inflammation, and anisocytosis in well-controlled type 2 diabetic patients with atherosclerotic cardiovascular disease

, 2020
Paweł Rostoff, Aleksander Siniarski, Maciej Haberka, Ewa Konduracka, Jadwiga Nessler, Grzegorz Gajos   +5 more
openalex   +2 more sources

Vascular Alterations in a Murine Model of Acute Graft-Versus-Host Disease Are Associated with Decreased Serum Levels of Adiponectin and an Increased Activity and Vascular Expression of Indoleamine 2,3-Dioxygenase [PDF]

, 2016
Peter Schmid, Abdellatif Bouazzaoui, Karin Schmid‐Zalaudek, Christoph Birner, Christian Schach, Lars S. Maier, Ernst Holler, Dierk Endemann   +7 more
openalex   +1 more source

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source

Pioglitazone Ameliorates Mitochondrial Oxidative Stress and Inflammation via AMPK‐Dependent Inhibition of Mitochondrial Fission in Leigh Syndrome

Cell Proliferation, EarlyView.
Pioglitazone suppresses mitochondrial excessive ROS generation and COX‐2 level through inhibition of Drp‐1 mediated mitochondrial fission in an AMPK‐dependent manner in LS. ABSTRACT Loss of function mutations of NDUFS4 resulted in Leigh syndrome, which is a progressive neurodegenerative disease and characterized by mitochondrial oxidative stress ...
Jie Luo, Ling Chen, Xiaoxian Zhang, Qiang Su, Xiaoya Zhou, Qizhou Lian   +5 more
wiley   +1 more source

Supplementary Table S4 from Sex-Specific Associations between Adiponectin and Leptin Signaling and Pancreatic Cancer Survival

, 2023
Ana Babić, Qiao-Li Wang, Alice A. Lee, Chen Yuan, Nader Rifai, Juhua Luo, Fred K. Tabung, Aladdin H. Shadyab, Jean Wactawski‐Wende, Nazmus Saquib, Jihye Kim, Peter Kraft, Howard D. Sesso, Julie E. Buring, Edward L. Giovannucci, JoAnn E. Manson, Meir J. Stampfer, Kimmie Ng, Charles S. Fuchs, Brian M. Wolpin   +19 more
openalex   +1 more source

Precision nutrition in weight loss and neuroendocrine control of people with obesity: The study protocol of a factorial randomised controlled trial (GenON Programme)

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Precision nutrition, guided by genetic testing, has emerged as a promising approach for managing obesity. However, robust clinical trials testing its effectiveness in real‐world dietary interventions remain scarce. The GenOn Programme aims to evaluate whether tailoring nutritional care based on genetic risk for obesity enhances weight ...
Karla P. Balbino, Ana Claudia P. Kravchychyn, Flávia G. Cândido, Mariana de Moura e Dias, Tiago Antônio de O. Mendes, Leandro Licursi de Oliveira, Luiza Carla V. Castro, Josefina Bressan, Ana Laura de la Garza, Fermín I. Milagro, María A. Zulet, Helen Hermana M. Hermsdorff   +11 more
wiley   +1 more source