Results 151 to 160 of about 140,016 (274)

Circulating levels of insulin‐like growth factor I (IGF‐I) and risk of multiple myeloma: An observational and Mendelian randomisation study

British Journal of Haematology, EarlyView.
Summary Evidence for an association between insulin‐like growth factors (IGF) and multiple myeloma (MM) is inconsistent. We examined total IGF‐I concentrations and risk of MM by combining baseline serological data among UK Biobank participants (n = 444 187; 732 incident MM) with a two‐sample Mendelian randomisation (MR) analysis using identified ...
Yolanda Benavente, Sara Hermosa, Nikos Papadimitriou, Alyssa Clay‐Gilmour, Elizabeth E. Brown, Jonathan N. Hofmann, Nathaniel Rothman, Qing Lan, Sonja I. Berndt, Demetrius Albanes, Mark Purdue, Mitchell J. Machiela, Stephen J. Chanock, Parveen Bhatti, Wendy Cozen, Aaron Norman, Susan L. Slager, James R. Cerhan, Vincent Rajkumar, Shaji K. Kumar, Celine M. Vachon, Anne J. Novak, Thomas M. Habermann, Brian K. Link, Gilles Salles, Herve Ghesquieres, Paige M. Bracci, Elizabeth Holly, Rosalie G. Griffin, Michelle A. T. Hildebrandt, Roel C. H. Vermeulen, P. Martijn Kolijn, Henrik Hjalgrim, Karin Ekström Smedby, Harindra Jayasekara, Simon Cheah, Alain Monnereau, Yu Chen, Alan Arslan, Yawei Zhang, Nicola J. Camp, Douglas W. Sborov, Afaf E. G. Osman, Elad Ziv, Immaculata De Vivo, Vijai Joseph, Lauren R. Teras, Alpa V. Patel, Eleanor Kane, Claire M. Vajdic, Adrien Guilloteau, Pierluigi Cocco, Laia Alemany, Juan Sainz, James McKay, Brenda M. Birmann, Delphine Casabonne   +56 more
wiley   +1 more source

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source

Comparative Predictive Value of Three Visceral Adiposity Indices for Cardiovascular Disease: A 17.5‐Year Korean Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Cardiovascular diseases (CVD) are the leading cause of death worldwide, with excess visceral adipose tissue (VAT) being identified as an independent indicator of poor cardiovascular outcomes. We examined the association between three indices of VAT, namely, metabolic score for visceral fat (METS‐VF), visceral adiposity index (VAI), and ...
A‐Ra Cho, Seok‐Jae Heo, Taehwa Han, Yu‐Jin Kwon   +3 more
wiley   +1 more source

Cold‐Induced Lipidomic Remodelling Is Associated With Brown Adipose Tissue Mean Radiodensity in Humans

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Cold exposure activates brown adipose tissue (BAT) and promotes thermogenic and metabolic adaptations. While BAT activation has been linked to improved cardiometabolic health, how acute cold exposure reshapes the circulating lipidome in humans remains incompletely understood.
Yu Zhang, Borja Martinez‐Tellez, Alida Kindt, Nicolas Drouin, Amy Harms, Thomas Hankemeier, Jonatan R. Ruiz, Lucas Jurado‐Fasoli   +7 more
wiley   +1 more source

Diagnosis and management of equine metabolic syndrome

Equine Veterinary Education, EarlyView.
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley   +1 more source

Prospective cohort study evaluating risk factors for the development of pasture-associated laminitis in the United Kingdom [PDF]

, 2016
Arita, Asplin, Bailey, Bailey, Beltowski, Blakesley, Borer, Bremer, Brooks, Carter, Cywinska, Dallmeier, Efstathiou, El-Mesallamy, Fesus, Finding, Firshman, Frank, Frank, Giles, Giordano, Greiner, Heinrichs, Henneke, Hinckley, Holbrook, Hotta, Huang, Ingelsson, Johnson, Kearns, Kim, Kullmann, Laat, Lam, Lavoie-Lamoureux, Lim, Luszczynski, Lygren, Macieira, Maleki, Mattu, Morgan, Orth, Ouchi, Pischon, Pleasant, Pollock, Popot, Pratt, Ragab, Reimers, Robin, Rosen, Ruan, Ruan, Ryu, Salazar-Ortiz, Salonen, Sandhu, Schultz, Smith, Stephenson, Takiguchi, Torres, Treiber, Treiber, Treiber, Treiber, Troncoso, Trujillo, Wannamethee, Wray, Wyse, Yang   +74 more
core   +2 more sources

Serum CTRP3 and CysC correlate with glucose, lipid, and bone metabolism in elderly patients with type 2 diabetes mellitus complicated with osteoporosis

Journal of Diabetes Investigation, EarlyView.
Serum levels of CTRP3 and CysC in elderly patients with T2DM and OP are closely associated with glucose‐lipid metabolism, bone mineral density, and bone metabolism markers. Combined detection of these two markers can assist in distinguishing OP in elderly patients with T2DM.
Yi‐Peng Wang, Yong Wang, Tao Chen, Gang Chen, Ze‐Yu Yang   +4 more
wiley   +1 more source

Interpretable machine learning models based on CMR radiomics for predicting left ventricular diastolic dysfunction in patients with metabolic‐associated steatotic liver disease and type 2 diabetes mellitus

Journal of Diabetes Investigation, EarlyView.
We developed an interpretable machine learning (ML) model combining cardiac magnetic resonance (CMR) radiomics and clinical data to assess left ventricular diastolic dysfunction (LVDD) risk in metabolic‐associated steatotic liver disease (MASLD)/type 2 diabetes mellitus (T2DM) patients, enabling proactive treatment.
Jinying Xia, Shaoyi Leng, Bin Xu, Guang Jin, Jianhui Li, Mingchen Zhang, Danzhen Yao, Ruiting Shen, Qifeng Hua   +8 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source