Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Molecular and cellular mechanisms of muscle-adipose tissue crosstalk driving sarcopenic obesity: an integrative review of human, animal, and in vitro models. [PDF]
Nutr Metab (Lond)Seliem MA, Ragab MA.
europepmc +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo +3 more
wiley +1 more source
Causal role of adipose tissue-derived adipokines in the pathogenesis of heart failure with preserved ejection fraction: experimental demonstration as the basis for clinical targeting. [PDF]
Eur Heart JPacker M.
europepmc +1 more source
Advanced Intelligent Systems, EarlyView.Inspired by the multi‐tissue architecture of the human fingertip dermis (A), this work introduces a mixture design using three PolyJet materials (AC/TM/GM) to expand the achievable elastomer property space (B). An inverse design pipeline (i‐Tac) is developed to map target optical/mechanical requirements to optimal material compositions (C), enabling ...
Wen Fan, Dandan Zhang
wiley +1 more source
Lim Homeobox 8 Is Essential for Beta Adrenergic Stimulation of Thermogenesis in Human Adipocytes. [PDF]
CellsGyurina K +8 more
europepmc +1 more source
Melatonin Levels in 89 Individuals With Smith Magenis Syndrome
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley +1 more source
Inflammatory Memory of Adipose Tissue Macrophages: From CD68 Footprint to Cardiometabolic and Cancer Risk During Weight Cycling. [PDF]
Int J Mol SciTomić Naglić D +9 more
europepmc +1 more source
Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy +16 more
wiley +1 more source
Brown adipose tissue in ruminants: development, thermogenic function, and nutritional regulation. [PDF]
Front Vet SciXiao ZH, Duan HW, Li L.
europepmc +1 more source