Results 171 to 180 of about 519,569 (305)

Adipose tissue magnetic resonance imaging in the newborn

, 2004
Infancy is a period of rapid adipose tissue accumulation, and influences during early development are plausible determinants of altered adiposity. The distribution, as well as the quantity of adipose tissue, is a marker of health and disease.
Uthaya, S.N., Modi, N., Bell, J.D.
core  

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Adipose Tissue Remodeling Beyond Weight Loss: New Insights Into Incretin-Based Therapies and Bariatric Surgery. [PDF]

Curr Obes Rep
Abud GF, de Freitas EC, Stanford KI.
europepmc   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Exploring the transcriptional crosstalk between adipose tissue and locoregional recurrence in breast cancer using independent component analysis. [PDF]

Funct Integr Genomics
Arjaans M, van der Vegt B, Linstra R, Fehrmann RSN, Bhattacharya A.   +4 more
europepmc   +1 more source

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Exercise-induced adipose tissue ADRB2-PGC1α-FGF21 signaling protects against pathological cardiac hypertrophy. [PDF]

iScience
Tan F, Wang Z, Cheng Y, Jiang P, Liao R, Zheng Z, Duan Q.   +6 more
europepmc   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source

Cancer-associated adipocytes: metabolic reprogramming, crosstalk and therapeutic implications in tumor progression. [PDF]

Signal Transduct Target Ther
Shi J, Abdel-Ghany S, Abdel-Fattah M, Hu X, Wadan AS, Sabit H.   +5 more
europepmc   +1 more source

Dual Modulation of Adipogenesis and Lipolysis Augments Facial Adipose Tissue Restoration. [PDF]

Comput Struct Biotechnol J
Taebnia N, Murawska M, Kemas AM, Sheng H, Wang Y, Xu J, Zhou T, Galanin I, Lauschke VM.   +8 more
europepmc   +1 more source