Gender differences in adiponectin levels among obese individuals and their association with cardiovascular disease. [PDF]
Sun Y +7 more
europepmc +1 more source
The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John +4 more
wiley +1 more source
Natural Killer Cell Dysfunction Is Emerging During Midlife Obesity. [PDF]
Biao R, Wang X, Fu J, Guo Y, He J, Du J.
europepmc +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
Adipose-Myocardial Border in Atrial Fibrillation. [PDF]
Fitzgibbons T, Tran KV.
europepmc +1 more source
AI‐generated anatomical highlighting improved surgeons' recognition of actual ureteral injuries during laparoscopic colorectal surgery, including recognition within predefined injury time‐code windows. No significant overall improvement was observed for pancreatic injury, and incorrect adverse‐event judgments did not increase in no‐injury videos. These
Shunjin Ryu +9 more
wiley +1 more source
Subcutaneous Adipose Tissue Attenuation Change on Chest CT Is Associated with Overall Survival After Allogeneic Hematopoietic Stem Cell Transplantation. [PDF]
Atçeken Z, Tan T, Peker Y.
europepmc +1 more source
ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative intervention remains essential for selected patients with ulcerative ...
Yoshiki Okita +4 more
wiley +1 more source
Human Adipose Allograft Restores Volume Through Host-mediated Tissue Replacement. [PDF]
Danilkovitch A, Saunders MC, Tom S.
europepmc +1 more source
Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents
This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer +3 more
wiley +1 more source

