ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith +9 more
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Maslinic Acid Alleviates Obesity-Associated Skeletal Muscle Atrophy and Adipose Tissue Dysfunction in Obese Mice. [PDF]
Wu SJ +4 more
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Identifying JAK2 and ANXA5 as Key Genes Linking Obstructive Sleep Apnea and Oxidative Stress via Machine Learning and Multilayer Transcriptomic Integration With Functional Validation. [PDF]
Li B, Wu Y, Chen P, Zhang Y, Xie J.
europepmc +1 more source
The Ageing Adipose Paradox: Implications for Metabolic Health. [PDF]
Matar DB +6 more
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Comparative Study of Mesenchymal Stem Cell Identity and Chondrogenic Differentiation Capacity of Human Nucleus Pulposus, Adipose and Bone Marrow Tissues Derived Mesenchymal Stem Cells. [PDF]
Kunkanjanawan H +6 more
europepmc +1 more source
Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets. [PDF]
Deng X, Shen Y, Sun Y, Lu L, Sun C.
europepmc +1 more source
1α,25(OH)<sub>2</sub> Vitamin D<sub>3</sub> Signaling in Adipose Tissue: Bridging Classical and Non-Classical Pathways in Metabolic Regulation Complexity. [PDF]
Mendes ALR +8 more
europepmc +1 more source
Bioprinted vascularized soft-tissue flaps with an integrated arterial-venous loop.
Fischer EO +12 more
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Presence of Adipose Differentiation-Related Protein in Rat Meibomian Gland Cells
Experimental Eye Research, 2007Adipose differentiation-related protein (ADRP) is an intrinsic lipid storage protein found in lipid droplets of different type of cells. ADRP has been recognized to be a specific marker of lipid accumulation and a marker of differentiated adipocytes. The purpose of this study was to determine whether ADRP was present in the cells of the meibomian gland.
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Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive triglyceride accumulation in hepatocytes. Expression of the lipid droplet protein adipose differentiation-related protein (ADRP) is increased in NAFLD, but whether this is causally linked to hepatic lipid metabolism is unclear. We postulated that a reduction in ADRP would ameliorate
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