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Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

The Ageing Adipose Paradox: Implications for Metabolic Health. [PDF]

open access: yesDiabetes Obes Metab
Matar DB   +6 more
europepmc   +1 more source

Bioprinted vascularized soft-tissue flaps with an integrated arterial-venous loop.

open access: yesCell Biomater
Fischer EO   +12 more
europepmc   +1 more source
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Presence of Adipose Differentiation-Related Protein in Rat Meibomian Gland Cells

Experimental Eye Research, 2007
Adipose differentiation-related protein (ADRP) is an intrinsic lipid storage protein found in lipid droplets of different type of cells. ADRP has been recognized to be a specific marker of lipid accumulation and a marker of differentiated adipocytes. The purpose of this study was to determine whether ADRP was present in the cells of the meibomian gland.
Atsushi Shiraishi   +2 more
exaly   +3 more sources

Reduction of Hepatosteatosis and Lipid Levels by an Adipose Differentiation-Related Protein Antisense Oligonucleotide

Gastroenterology, 2007
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive triglyceride accumulation in hepatocytes. Expression of the lipid droplet protein adipose differentiation-related protein (ADRP) is increased in NAFLD, but whether this is causally linked to hepatic lipid metabolism is unclear. We postulated that a reduction in ADRP would ameliorate
Yumi Imai   +2 more
exaly   +3 more sources

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